High red blood cell distribution width is closely associated with nonalcoholic fatty liver disease

2014 ◽  
Vol 26 (2) ◽  
pp. 174-178 ◽  
Author(s):  
Wen Yang ◽  
Haiyan Huang ◽  
Yuzhu Wang ◽  
Xiaohong Yu ◽  
Zhijian Yang
Keyword(s):  
Liver Disease ◽  
Blood Cell ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Red Blood Cell ◽  
Fatty Liver Disease ◽  
Cell Distribution ◽  
Distribution Width ◽  
Nonalcoholic Fatty Liver ◽  
Red Blood Cell Distribution

scholarly journals The association between white blood cell subtypes and prevalence and incidence of nonalcoholic fatty liver disease

2019 ◽  
Vol 17 ◽  
pp. 205873921983447
Author(s):  
Hongmei Zhang ◽  
Yixin Niu ◽  
Hongxia Gu ◽  
Shuai Lu ◽  
Weikang Su ◽  
...  
Keyword(s):  
Liver Disease ◽  
Blood Cell ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
White Blood Cell ◽  
Fatty Liver Disease ◽  
Complete Information ◽  
Nonalcoholic Fatty Liver ◽  
Independent Risk Factors

The association between white blood cell (WBC) and nonalcoholic fatty liver disease (NAFLD) has been studied before, but whether different WBC subtypes were related to NAFLD was not detailed. The aim of our study was to investigate the relationship between WBC subtypes and NAFLD cross-sectionally and prospectively. The detailed research design has been described previously. At baseline, there were 9930 participants who had complete information, in the end a total of 8079 participants (2588 men and 5491 women) were eventually included in this study. Hepatic ultrasound examination was performed on each participant at baseline and at the end of follow-up. Alcohol abuse and hepatitis were excluded. WBC subtypes and other serum indices were measured at baseline. We found that the total WBC, neutrophil, and lymphocyte counts were independently associated with the prevalence and incidence of NAFLD. After multiple adjustments for age, gender, body mass index (BMI), insulin, HOMA-IR, TG, TC, LDL, and HDL, increased odds ratios (ORs) for new onset NAFLD were observed from the 1st to the 4th quartiles of WBC, neutrophil, and lymphocyte (all P < 0.001 for trend). In conclusion, total WBC counts, neutrophils, and lymphocytes were all independent risk factors for NAFLD in the rural Chinese population. The association was independent of insulin resistance.

scholarly journals Diagnostic Accuracy of Platelet Count and Platelet Indices in Noninvasive Assessment of Fibrosis in Nonalcoholic Fatty Liver Disease Patients

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Tamara Milovanovic Alempijevic ◽  
Milica Stojkovic Lalosevic ◽  
Igor Dumic ◽  
Nevena Jocic ◽  
Aleksandra Pavlovic Markovic ◽  
...  
Keyword(s):  
Platelet Count ◽  
Liver Disease ◽  
Liver Fibrosis ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Liver Steatosis ◽  
Distribution Width ◽  
Nonalcoholic Fatty Liver ◽  
Significant Difference

Objective. Keeping in mind the rising prevalence of nonalcoholic fatty liver disease (NAFLD) and the need to establish noninvasive tests for its detection, the aim of our study was to investigate whether platelet count (PC), mean platelet volume (MPV), and platelet distribution width (PDW) can predict the presence of liver fibrosis in this group of patients. Methods. In 98 patients with NAFLD and 60 healthy volunteers, complete blood counts with automated differential counts were performed and values of PC, PDW, MPV, and PCT were analyzed. Results. Patients with NAFLD had lower PC and higher MPV, PCT, and PDW compared to the controls (P < 0.05). When NAFLD group was stratified according to severity of liver fibrosis, there was a statistically significant difference in the average values of PDW and PC between the groups (P < 0.05). Conclusion. Patients with NAFLD have significantly higher values of PCT, PDW, and MPV when compared to the healthy controls. Further studies are needed to establish their potential use for prediction of the degree of liver steatosis and fibrosis in NAFLD patients.

Relationship between white blood cell count and nonalcoholic fatty liver disease

2010 ◽  
Vol 42 (12) ◽  
pp. 888-894 ◽  
Author(s):  
Yong-Jae Lee ◽  
Hye-Ree Lee ◽  
Jae-Yong Shim ◽  
Byung-Soo Moon ◽  
Jung-Hyun Lee ◽  
...  
Keyword(s):  
Liver Disease ◽  
Blood Cell ◽  
Fatty Liver ◽  
Cell Count ◽  
Nonalcoholic Fatty Liver Disease ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Fatty Liver Disease ◽  
Blood Cell Count ◽  
Nonalcoholic Fatty Liver
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