Comparison of 800 and 3700 MBq iodine-131 for the postoperative ablation of thyroid remnant in patients with low-risk differentiated thyroid cancer

2012 ◽  
Vol 33 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Meltem Caglar ◽  
Fani M. Bozkurt ◽  
Ceren Kapulu Akca ◽  
Sezen Elhan Vargol ◽  
Miyase Bayraktar ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Low Risk ◽  
Thyroid Remnant ◽  
Iodine 131

scholarly journals Low versus high radioiodine activity for ablation of the thyroid remnant after thyroidectomy in Han Chinese with low-risk differentiated thyroid cancer

2017 ◽  
Vol Volume 10 ◽  
pp. 4051-4057 ◽  
Author(s):  
Rong-Bin Lv ◽  
Qing-Gang Wang ◽  
Chao Liu ◽  
Fang Liu ◽  
Qing Zhao ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Han Chinese ◽  
Low Risk ◽  
Thyroid Remnant

scholarly journals Outpatient Thyroid Remnant Ablation Using Repeated Low 131-Iodine Activities (740 MBq/20 mCi × 2) in Patients with Low-Risk Differentiated Thyroid Cancer

2012 ◽  
Vol 97 (3) ◽  
pp. 871-880 ◽  
Author(s):  
Jérôme Clerc ◽  
Marie Bienvenu-Perrard ◽  
Caroline Pichard de Malleray ◽  
Françoise Dagousset ◽  
Thierry Delbot ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Low Risk ◽  
Thyroid Remnant ◽  
Remnant Ablation

scholarly journals Letter Response to “Investigating the Sources of Heterogeneity in Systematic Review of Recurrence Rate after Hemi-Thyroidectomy for Low-Risk Well-Differentiated Thyroid Cancer”

2021 ◽  
Vol 10 (2) ◽  
pp. 183-184
Author(s):  
Samuel Chan ◽  
Katarina Karamali ◽  
Anna Kolodziejczyk ◽  
Georgio Oikonomou ◽  
John Watkinson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Thyroid Cancer ◽  
Recurrence Rate ◽  
Differentiated Thyroid Cancer ◽  
Low Risk ◽  
Well Differentiated

Lowest effective 131I activity for thyroid remnant ablation of differentiated thyroid cancer patients

2015 ◽  
Vol 54 (03) ◽  
pp. 137-143 ◽  
Author(s):  
A.-S. Moldovan ◽  
M. Ruhlmann ◽  
R. Görges ◽  
A. Bockisch ◽  
S. Rosenbaum-Krumme ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer ◽  
Absorbed Dose ◽  
Thyroid Remnant ◽  
Remnant Ablation ◽  
Dose Threshold ◽  
131I Activity ◽  
Pet Ct ◽  
Absorbed Radiation Dose

SummaryAim: A theoretical dosimetry-based model was applied to estimate the lowest effective radioiodine activity for thyroid remnant ablation of low-risk differentiated thyroid cancer patients. Patients, methods: The model is based on the distribution of the absorbed (radiation) dose per administered radioiodine activity and the absorbed dose threshold of 300 Gy for thyroid remnants, the level believed to destroy most thyroid remnants. For this purpose, 124I PET/CT images of 49 thyroid-ectomised patients were retrospectively analysed to measure the distribution of the (average) absorbed doses to thyroid remnant per administered 131I activity. The fraction of thyroid remnants that received at least 300 Gy was determined for standard activities between 0.37 and 5.55 GBq. The lower activity was considered to be equally effective to that obtained with higher activity if the (absolute) fraction difference was below 5%. Results: A total of 62 thyroid remnants were included. The medians and ranges (in parentheses) for the absorbed dose per unit 131I activity were 359 Gy/GBq (34 to 1825 Gy/ GBq). The fractions of thyroid remnants receiving more than 300 Gy at different therapy activities (within parentheses) were 60% (1.11 GBq), 76% (1.85 GBq), 79% (2.22 GBq), and 81–82% for activities between 2.59 and 3.70 GBq. The therapy activity of 1.11 GBq is considerably less effective than that of 1.85 or 2.22 GBq; therapy activities were equally effective in the range between 2.22 to 3.70 GBq. Conclusion: On the basis of the model and the patients' data included, the lowest effective therapy activity appears to be approximately 2.2 GBq to ablate thyroid remnants. The results of this study may help to guide the design of prospective clinical studies.

Thyroid remnant ablation in differentiated thyroid cancer

2015 ◽  
Vol 36 (11) ◽  
pp. 1100-1106 ◽  
Author(s):  
Alfredo Campennì ◽  
Luca Giovanella ◽  
Salvatore A. Pignata ◽  
Maria A. Violi ◽  
Massimiliano Siracusa ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Thyroid Remnant ◽  
Remnant Ablation
Sign in / Sign up

Export Citation Format

Share Document