Treatment Guidelines for Gastrointestinal Stromal Tumors in Children and Young Adults

2012 ◽  
Vol 34 ◽  
pp. S69-S72 ◽  
Author(s):  
Katherine A. Janeway ◽  
Alberto Pappo
2005 ◽  
Vol 27 (4) ◽  
pp. 179-187 ◽  
Author(s):  
Sonam Prakash ◽  
Lisa Sarran ◽  
Nicholas Socci ◽  
Ronald P DeMatteo ◽  
Jonathan Eisenstat ◽  
...  

Apmis ◽  
2013 ◽  
Vol 121 (10) ◽  
pp. 938-944 ◽  
Author(s):  
Guhyun Kang ◽  
Young Soo Park ◽  
Eun-Sun Jung ◽  
Mee Joo ◽  
Mi Seon Kang ◽  
...  

2015 ◽  
Vol 7s1 ◽  
pp. BIC.S25045 ◽  
Author(s):  
Anna Koumarianou ◽  
Panagiota Economopoulou ◽  
Panagiotis Katsaounis ◽  
Konstantinos Laschos ◽  
Petroula Arapantoni-Dadioti ◽  
...  

Gastrointestinal Stromal tumors (GIST) are the most common sarcomas of the gastrointestinal tract, with transformation typically driven by activating mutations of cKIT and less commonly platelet-derived growth factor receptor alpha (PDGFRA). Successful targeting of tyrosine-protein kinase Kit with imatinib, a tyrosine kinase inhibitor, has had a major impact in the survival of patients with GIST in both the adjuvant and metastatic setting. A recent modification of treatment guidelines for patients with localized, high-risk GIST extended the adjuvant treatment duration from 1 year to 3 years. In this paper, we review the clinical data of patients with GIST treated in the Oncology Outpatient Unit of “Attikon” University Hospital and aim to assess which patients are eligible for prolongation of adjuvant imatinib therapy as currently suggested by treatment recommendations.


2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Laura N. Zamproni ◽  
Reinaldo T. Ribeiro ◽  
Marina Cardeal

Recurrent painful ophthalmoplegic neuropathy, previously known as ophthalmoplegic migraine, is a rare condition that affects children and young adults. Its cause and classification are still controversial and, consequently, there are no published treatment guidelines or consensus. Glucocorticoids seem to be beneficial for some patients, but there is no established treatment when failure of this therapy occurs. The aim of this study was to report a case where pregabalin was successfully used after failure of glucocorticoid therapy in a patient with recurrent painful ophthalmoplegic neuropathy.


Cancer ◽  
2010 ◽  
Vol 116 (22) ◽  
pp. 5126-5137 ◽  
Author(s):  
Jean-Yves Blay ◽  
Margaret von Mehren ◽  
Martin E. Blackstein

JAMA Surgery ◽  
2017 ◽  
Vol 152 (5) ◽  
pp. 443 ◽  
Author(s):  
Katherine E. Fero ◽  
Taylor M. Coe ◽  
Paul T. Fanta ◽  
Chih-Min Tang ◽  
James D. Murphy ◽  
...  

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