Olaparib Maintenance Therapy in Patients With Platinum-Sensitive Relapsed Serous Ovarian Cancer

Jonathan Ledermann; Philipp Harter; Charlie Gourley; Michael Friedlander; Ignace Vergote; Gordon Rustin; Clare L. Scott; Werner Meier; Ronnie Shapira-Frommer; Tamar Safra; Daniela Matei; Anitra Fielding; Stuart Spencer; Brian Dougherty; Maria Orr; Darren Hodgson; J. Carl Barrett; Ursula Matulonis

doi:10.1097/ogx.0000000000000107

Olaparib Maintenance Therapy in Patients With Platinum-Sensitive Relapsed Serous Ovarian Cancer

Obstetrical & Gynecological Survey ◽

10.1097/ogx.0000000000000107 ◽

2014 ◽

Vol 69 (10) ◽

pp. 594-596 ◽

Cited By ~ 4

Author(s):

Jonathan Ledermann ◽

Philipp Harter ◽

Charlie Gourley ◽

Michael Friedlander ◽

Ignace Vergote ◽

...

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Serous Ovarian Cancer ◽

Platinum Sensitive

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Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and aBRCAmutation: Overall survival adjusted for postprogression poly(adenosine diphosphate ribose) polymerase inhibitor therapy

Cancer ◽

10.1002/cncr.29995 ◽

2016 ◽

Vol 122 (12) ◽

pp. 1844-1852 ◽

Cited By ~ 48

Author(s):

Ursula A. Matulonis ◽

Philipp Harter ◽

Charlie Gourley ◽

Michael Friedlander ◽

Ignace Vergote ◽

...

Keyword(s):

Ovarian Cancer ◽

Overall Survival ◽

Maintenance Therapy ◽

Adenosine Diphosphate ◽

Inhibitor Therapy ◽

Serous Ovarian Cancer ◽

Platinum Sensitive ◽

Polymerase Inhibitor

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Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer and a BRCA mutation: Overall survival adjusted for post-progression PARP inhibitor therapy

Gynecologic Oncology ◽

10.1016/j.ygyno.2015.01.015 ◽

2015 ◽

Vol 137 ◽

pp. 8

Author(s):

U.A. Matulonis ◽

P. Harter ◽

C. Gourley ◽

M. Friedlander ◽

I.B. Vergote ◽

...

Keyword(s):

Ovarian Cancer ◽

Overall Survival ◽

Maintenance Therapy ◽

Brca Mutation ◽

Parp Inhibitor ◽

Inhibitor Therapy ◽

Serous Ovarian Cancer ◽

Platinum Sensitive

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Health-Related Quality of Life (Hrqol) During Olaparib Maintenance Therapy in Patients with Platinum-Sensitive Relapsed Serous Ovarian Cancer (Psr Soc) and a Brca Mutation (Brcam)

Annals of Oncology ◽

10.1093/annonc/mdu338.11 ◽

2014 ◽

Vol 25 ◽

pp. iv308 ◽

Cited By ~ 2

Author(s):

J.A. Ledermann ◽

P. Harter ◽

C. Gourley ◽

M. Friedlander ◽

I.B. Vergote ◽

...

Keyword(s):

Quality Of Life ◽

Ovarian Cancer ◽

Maintenance Therapy ◽

Brca Mutation ◽

Serous Ovarian Cancer ◽

Health Related Quality ◽

Platinum Sensitive ◽

Related Quality ◽

Health Related

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Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial

The Lancet Oncology ◽

10.1016/s1470-2045(14)70228-1 ◽

2014 ◽

Vol 15 (8) ◽

pp. 852-861 ◽

Cited By ~ 793

Author(s):

Jonathan Ledermann ◽

Philipp Harter ◽

Charlie Gourley ◽

Michael Friedlander ◽

Ignace Vergote ◽

...

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Retrospective Analysis ◽

Serous Ovarian Cancer ◽

Phase 2 ◽

Platinum Sensitive ◽

Phase 2 Trial

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Quality of life during olaparib maintenance therapy in platinum-sensitive relapsed serous ovarian cancer

British Journal of Cancer ◽

10.1038/bjc.2016.348 ◽

2016 ◽

Vol 115 (11) ◽

pp. 1313-1320 ◽

Cited By ~ 32

Author(s):

Jonathan A Ledermann ◽

Philipp Harter ◽

Charlie Gourley ◽

Michael Friedlander ◽

Ignace Vergote ◽

...

Keyword(s):

Quality Of Life ◽

Ovarian Cancer ◽

Maintenance Therapy ◽

Serous Ovarian Cancer ◽

Platinum Sensitive

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Tolerability of olaparib tablets as maintenance therapy in patients with BRCA-mutated (BRCAm) platinum-sensitive relapsed serous ovarian cancer (PSR SOC): Phase III SOLO2/AGO-OVAR2.23 trial

10.1055/s-0038-1671027 ◽

2018 ◽

Author(s):

LC Hanker ◽

F Heitz ◽

TW Park-Simon ◽

M Gropp-Meier ◽

B Ataseven ◽

...

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Phase Iii ◽

Serous Ovarian Cancer ◽

Platinum Sensitive

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Analysis of intermediate clinical endpoints from a Phase II trial of olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC)

Gynecologic Oncology ◽

10.1016/j.ygyno.2014.03.152 ◽

2014 ◽

Vol 133 ◽

pp. 54-55 ◽

Cited By ~ 2

Author(s):

U.A. Matulonis ◽

P. Harter ◽

C. Gourley ◽

M. Friedlander ◽

I.B. Vergote ◽

...

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Phase Ii ◽

Phase Ii Trial ◽

Serous Ovarian Cancer ◽

Clinical Endpoints ◽

Platinum Sensitive

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Faculty Opinions recommendation of Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718142792.793485310 ◽

2013 ◽

Author(s):

Maurie Markman

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Platinum Sensitive

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Niraparib maintenance therapy in patients with platinum-sensitive recurrent ovarian cancer and a time-to-progression after penultimate platinum-based chemotherapy of 6-12 or >12 months: a subgroup analysis of the phase III NORA trial

Gynecologic Oncology ◽

10.1016/s0090-8258(21)00681-8 ◽

2021 ◽

Vol 162 ◽

pp. S18

Author(s):

Qidan Huang ◽

Xiaohua Wu ◽

Jianqing Zhu ◽

Danqing Wang ◽

Jiaxin Yang ◽

...

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Subgroup Analysis ◽

Recurrent Ovarian Cancer ◽

Phase Iii ◽

Time To Progression ◽

Platinum Sensitive ◽

Platinum Based Chemotherapy

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Olaparib tablets as maintenance therapy in patients with platinum-sensitive relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a final analysis of a double-blind, randomised, placebo-controlled, phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(21)00073-5 ◽

2021 ◽

Author(s):

Andrés Poveda ◽

Anne Floquet ◽

Jonathan A Ledermann ◽

Rebecca Asher ◽

Richard T Penson ◽

...

Keyword(s):

Ovarian Cancer ◽

Maintenance Therapy ◽

Final Analysis ◽

Phase 3 ◽

Double Blind ◽

Platinum Sensitive

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