Photoreceptor Layer Map Using Spectral-Domain Optical Coherence Tomography

2009 ◽  
Vol 86 (12) ◽  
pp. E1320-E1327 ◽  
Author(s):  
Ji Eun Lee ◽  
Dae Won Lim ◽  
Han Yong Bae ◽  
Hyun Jin Park
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Photoreceptor Layer

scholarly journals Photoreceptor Layer Thinning over Drusen in Eyes with Age-Related Macular Degeneration Imaged In Vivo with Spectral-Domain Optical Coherence Tomography

Ophthalmology ◽  
2009 ◽  
Vol 116 (3) ◽  
pp. 488-496.e2 ◽  
Author(s):  
Stefanie G. Schuman ◽  
Anjum F. Koreishi ◽  
Sina Farsiu ◽  
Sin-ho Jung ◽  
Joseph A. Izatt ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Photoreceptor Layer ◽  
Age Related

scholarly journals Measurement of Photoreceptor Layer in Glaucoma: A Spectral-Domain Optical Coherence Tomography Study

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Ning Fan ◽  
Nina Huang ◽  
Dennis Shun Chiu Lam ◽  
Christopher Kai-shun Leung
Keyword(s):  
Optical Coherence Tomography ◽  
Confidence Interval ◽  
Outer Nuclear Layer ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Photoreceptor Layer ◽  
Intraclass Correlation Coefficients ◽  
Spectral Domain Oct

Objective.To measure and compare photoreceptor layer thickness between normal and glaucomatous eyes using spectral-domain optical coherence tomography (OCT).Methods. Thirty-eight healthy normal volunteers and 47 glaucoma patients were included in the analysis. One eye from each participant was randomly selected for macula imaging by a spectral-domain OCT (3D OCT-1000, Topcon, Tokyo, Japan). The foveal and parafoveal (1.5 mm from the fovea) outer nuclear layer (ONL) and inner and outer segments (IS+OS) layer thicknesses were measured by a single masked observer. The measurements were repeated 3 times in a random sample of 30 normal eyes to determine the repeatability coefficient and intraclass correlation coefficient.Results.The measurement variabilities of photoreceptor thickness were low. The respective intraclass correlation coefficients of ONL and IS+OS thicknesses were 0.96 (95% confidence interval: 0.94–0.98) and 0.82 (95% confidence interval 0.70–0.90). While there were no differences in parafoveal ONL and IS+OS thicknesses between normal and glaucoma groups (), the foveal ONL thickness was greater in glaucomatous eyes () than in normal eyes.Conclusions.Glaucomatous damage may involve structural change in the photoreceptor layer.

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