scholarly journals Miller Fisher Syndrome Mimicking Ocular Myasthenia Gravis

2012 ◽  
Vol 89 (12) ◽  
pp. e118-e123 ◽  
Author(s):  
Scott A. Anthony ◽  
Matthew J. Thurtell ◽  
R. John Leigh
Keyword(s):  
Myasthenia Gravis ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

Pediatric Miller Fisher Syndrome and Ocular Myasthenia Gravis (A Reminder of Clinical Mimicry): A Case Report

2021 ◽  
Author(s):  
Zakaria Barsoum
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptors ◽  
Correct Diagnosis ◽  
Clinical Signs ◽  
Autoimmune Disorder ◽  
Miller Fisher Syndrome ◽  
Neurological Deficits ◽  
Fisher Syndrome ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

AbstractMiller Fisher syndrome (MFS) is a rare immune-mediated neuropathy that often presents with diplopia and bilateral external ophthalmoplegia. Other neurological deficits may occur such as ataxia and areflexia but not in all cases. Although MFS is a clinical diagnosis, serological confirmation is possible by identifying the anti-GQ1b antibody found in the majority of patients. Myasthenia gravis is an autoimmune disorder of the availability of acetylcholine receptors in the neuromuscular junction. Ocular myasthenia gravis is a disease subtype characterized by variable patterns of weakness of extraocular muscles, eyelid elevator, and orbicular muscle in which the initial sign in most adults and children is ptosis. We report a child with MFS who presented with clinical signs suggestive of ocular myasthenia gravis, but in whom the correct diagnosis was made on the basis of serological testing for the anti-GQ1b antibody. We aim to highlight the similarity between the two rare conditions and address the importance of early liaison with neurologists and ophthalmologists in reaching to the proper diagnosis.

Ptosis and Neuromuscular Syndromes

2014 ◽  
pp. 83-119
Author(s):  
Shirley H. Wray
Keyword(s):  
Myasthenia Gravis ◽  
Neuromuscular Transmission ◽  
Clinical Importance ◽  
Progressive External Ophthalmoplegia ◽  
Oculopharyngeal Muscular Dystrophy ◽  
Fisher Syndrome ◽  
Ocular Myasthenia ◽  
Kearns Sayre Syndrome ◽  
Ocular Myasthenia Gravis

emphasizes the clinical importance of a careful patient history detailing the onset of ptosis, its variability, and its progression. A pattern of ocular and generalized muscle weakness is a central diagnostic attribute of impaired nerve conduction due to disease of the neuromuscular junction. Generalized myasthenia gravis, ocular myasthenia gravis, MuSK-myasthenia gravis, and a case of the Lambert-Eaton syndrome illustrate the spectrum of disorders of neuromuscular transmission. The syndrome known as chronic progressive external ophthalmoplegia is by far the most common of the mitochondrial myopathies progressing to the multisystem failure that is characteristic of the Kearns-Sayre syndrome. A case of Kearns-Sayre syndrome followed for 34 years is a unique case study. Two inherited forms of myopathy, oculopharyngeal muscular dystrophy and myotonic dystrophy, are included, together with a patient with the Guillain-Barré syndrome variant, Fisher syndrome. These disorders should always be considered in the differential diagnosis of bilateral progressive ptosis.

Abstract #1154: Ocular Myasthenia Gravis in the Setting of Graves’ Disease

2016 ◽  
Vol 22 ◽  
pp. 277-278
Author(s):  
Lima Lawrence ◽  
Aleida Rodriguez ◽  
Tahira Yasmeen ◽  
Erin Drever
Keyword(s):  
Myasthenia Gravis ◽  
Graves Disease ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

The diagnosis and management of ocular myasthenia gravis

2019 ◽  
Vol 5 (1-2) ◽  
pp. 3-8
Author(s):  
Gordon Plant
Keyword(s):  
Myasthenia Gravis ◽  
Severe Form ◽  
Differential Diagnostics ◽  
Diagnosis And Management ◽  
Ocular Myasthenia ◽  
Clinical Presentations ◽  
Ocular Myasthenia Gravis

Ocular myasthenia is not the most severe form of myasthenia but it might cause certain difficulties to diagnose. In this article, we shall discuss the clinical presentations of ocular myasthenia, its differential diagnostics, examinations and management. Keywords: ocular myasthenia gravis, diagnosis, examination, management.

Pediatric Autoimmune Ocular Myasthenia Gravis: Evaluation of Presentation and Treatment Outcomes in a Large Cohort

2021 ◽  
Vol 118 ◽  
pp. 12-19
Author(s):  
Kristen S. Fisher ◽  
Jason Gill ◽  
Hannah F. Todd ◽  
Michael B. Yang ◽  
Michael A. Lopez ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Treatment Outcomes ◽  
Large Cohort ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

scholarly journals Ocular myasthenia gravis – How effective is low dose prednisone long term?

2021 ◽  
Vol 420 ◽  
pp. 117274
Author(s):  
Rashmi Verma ◽  
Gil I. Wolfe ◽  
Mark J. Kupersmith
Keyword(s):  
Myasthenia Gravis ◽  
Low Dose ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
Dose Prednisone
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