scholarly journals HIV Testing Rates and Outcomes in a South African Community, 2001-2006: Implications for Expanded Screening Policies

2009 ◽  
Vol 51 (3) ◽  
pp. 310-316 ◽  
Author(s):  
Michael D April ◽  
Rochelle P Walensky ◽  
Yuchiao Chang ◽  
Jennifer Pitt ◽  
Kenneth A Freedberg ◽  
...  
2017 ◽  
Vol 72 (2) ◽  
pp. 168-172 ◽  
Author(s):  
Alain Vandormael ◽  
Tulio de Oliveira ◽  
Frank Tanser ◽  
Till Bärnighausen ◽  
Joshua T Herbeck

BackgroundUndiagnosed HIV infections could undermine efforts to reverse the global AIDS epidemic by 2030. In this study, we estimated the percentage of HIV-positive persons who remain undiagnosed within a hyperendemic South African community.MethodsThe data come from a population-based surveillance system located in the Umkhanyakude district of the northern KwaZulu-Natal province, South Africa. We annually tested 38 661 adults for HIV between 2005 and 2016. Using the HIV-positive test results of 12 039 (31%) participants, we then back-calculated the incidence of infection and derived the number of undiagnosed cases from this result.ResultsThe percentage of undiagnosed HIV cases decreased from 29.3% in 2005 to 15.8% in 2011. During this period, however, approximately 50% of the participants refused to test for HIV, which lengthened the average time from infection to diagnosis. Consequently, the percentage of undiagnosed HIV cases reversed direction and steadily increased from 16.1% to 18.9% over the 2012–2016 period.ConclusionsResults from this hyperendemic South African setting show that the HIV testing rate is low, with long infection times, and an unsatisfactorily high percentage of undiagnosed cases. A high level of repeat HIV testing is needed to minimise the time from infection to diagnosis if the global AIDS epidemic is to be reversed within the next two decades.


2006 ◽  
Vol 33 (8) ◽  
pp. 524-526 ◽  
Author(s):  
Keren Middelkoop ◽  
Landon Myer ◽  
Joalida Smit ◽  
Robin Wood ◽  
Linda-Gail Bekker

2017 ◽  
Vol 20 ◽  
pp. 21753 ◽  
Author(s):  
Tendesayi Kufa ◽  
Ayesha BM Kharsany ◽  
Cherie Cawood ◽  
David Khanyile ◽  
Lara Lewis ◽  
...  

PLoS ONE ◽  
2008 ◽  
Vol 3 (10) ◽  
pp. e3501 ◽  
Author(s):  
Ntombizodumo B. Mkwanazi ◽  
Deven Patel ◽  
Marie-Louise Newell ◽  
Nigel C. Rollins ◽  
A. Coutsoudis ◽  
...  

2018 ◽  
Author(s):  
Tonderai Mabuto ◽  
Bhakti Hansoti ◽  
Salome Charalambous ◽  
Christopher Hoffman

2006 ◽  
Vol 17 (3) ◽  
pp. 176-179 ◽  
Author(s):  
J Smit ◽  
K Middelkoop ◽  
L Myer ◽  
S Seedat ◽  
L-G Bekker ◽  
...  

Research on willingness to participate in HIV vaccine trials is important in preparations for HIV vaccine research, but there are few data from sub-Saharan Africa. We interviewed 198 individuals in a peri-urban South African community immediately after enrolment into an HIV vaccine preparedness study on their willingness to participate in hypothetical vaccine trials. Overall 23% of participants ( n = 46) said that they would be willing to participate in an HIV vaccine trial. Willingness was associated with increasing age, male gender, and increasing knowledge about vaccines generally and HIV vaccines specifically. In multivariate analysis, a 1-unit increase in HIV vaccine knowledge score was associated with a 10-fold increase in willingness to participate (adjusted odds ratio, 10.72, 95% confidence intervals: 4.40–26.12). These results suggest that while willingness to participate in HIV vaccine trials is relatively low in this setting, educational campaigns may have a substantial impact on individuals' willingness to participate in research.


2017 ◽  
Vol 38 (8) ◽  
pp. 1142-1169 ◽  
Author(s):  
Nicholas Tarantino ◽  
Nada M. Goodrum ◽  
Christina Salama ◽  
Rebecca H. LeCroix ◽  
Karie Gaska ◽  
...  

This study examined South African early adolescent youth (aged 10-14 years) and their female caregivers ( N = 99 dyads) participating in an HIV prevention intervention over a period of 8 months. We examined youth perceptions of neighborhood cohesion, safety, and collective monitoring as they related to concurrent and longitudinal associations with youth (externalizing behavior and hope about the future) and family (parent-youth relationship quality, parental involvement, and parental responsiveness to sex communication) functioning while controlling for baseline characteristics. Neighborhood perceptions were significantly associated ( p < .05) with short- and longer term outcomes. Gender differences suggested a greater protective association of perceived neighborhood conditions with changes in functioning for boys versus girls. Unexpected associations were also observed, including short-term associations suggesting a link between better neighborhood quality and poorer family functioning. We account for the culture of this South African community when contextualizing our findings and conclude with recommendations for interventions targeting neighborhood contexts.


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