Pulmonary infections remain one of the most important causes of morbidity and mortality in HIV-infected people, and one of the most common causes of hospital admission of these persons. It is often difficult to diagnose pneumonia in patients with compromised immunity, with a wide range of opportunistic infections (bacterial, fungal, viral, parasitic, tuberculosis, etc.), but also an extensive list of other causes of fever and lung imaging changes, such as pulmonary embolism, tumors, atelectasis, or the simultaneous development of infections in other systems (digestive, renal), requiring more tests to confirm the diagnosis in immunocompromised patient compared to the immunocompetent.