Brain Contrast-Enhanced Ultrasound Evaluation of a Pediatric Swine Model

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Misun Hwang ◽  
Kristina Khaw ◽  
Anush Sridharan ◽  
Laura Poznick ◽  
Thomas Hallowell ◽  
...  
Keyword(s):  
Swine Model ◽  
Contrast Enhanced Ultrasound ◽  
Ultrasound Evaluation ◽  
Contrast Enhanced

scholarly journals Diagnostic Value of Contrast-Enhanced Ultrasound Evaluation of Malignant and Benign Solitary Thyroid Nodules

2016 ◽  
Vol 70 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Pēteris Priedītis ◽  
Maija Radziņa ◽  
Ilze Štrumfa ◽  
Zenons Narbuts ◽  
Arturs Ozoliņs ◽  
...  
Keyword(s):  
Contrast Enhancement ◽  
Thyroid Nodules ◽  
Fine Needle Biopsy ◽  
Diagnostic Value ◽  
Contrast Enhanced Ultrasound ◽  
Clinical Value ◽  
Additional Tool ◽  
Ultrasound Evaluation ◽  
Contrast Enhanced ◽  
Benign Nodules

Abstract The aim of the study was to investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) in differentiating benign and malignant thyroid nodules. Thirty-five patients with morphologically proved thyroid nodules (17 malignant; 18 benign), underwent CEUS examination. Five enhancement patterns were evaluated: vascularisation, homogeneity, presence of peripheral rim type enhancement, wash-out rate of the contrast medium, and enhancement using microvascular imaging application. Time-intensity curves (TIC) were analysed in post-processing and defined as three types: slow versus rapid and stable versus rapid biphasic wash-out. Diagnostic value of the listed CEUS parameters was calculated. The results showed medium strength correlation between morphology (benign versus malignant nodule) and type of TIC curve rs = 0.38 (p = 0.021), as well as between mode of contrast enhancement rs = 0.39 (p = 0.022) and wash-out pattern rs =0.39 (p = 0.024). The overall pooled sensitivity of selected diagnostic parameters was 82%, specificity 57%, and accuracy 70%. Malignant nodules were characterised by iso- or hypovascular contrast enhancement and slow wash-out, while benign nodules showed hypervascular enhancement with rapid wash-out TIC curve and rim-like pattern. The CEUS patterns significantly differed between malignant and benign thyroid nodules with high diagnostic accuracy. Thus, CEUS has important clinical value as an additional tool to ultrasound and fine needle biopsy.

scholarly journals Contrast-Enhanced Ultrasound Evaluation of Mifepristone for Treatment of Low-Risk Cesarean Scar Pregnancy

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Xi Xiong ◽  
Chun-yan Gao ◽  
De-mei Ying ◽  
Ping Yan ◽  
Zhi-jia Zhang ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Low Risk ◽  
Contrast Enhanced Ultrasound ◽  
Intrauterine Pregnancy ◽  
Cesarean Scar Pregnancy ◽  
Cesarean Scar ◽  
Ultrasound Evaluation ◽  
Contrast Enhanced ◽  
Significant Difference ◽  
Before And After

Purpose. The effect of mifepristone for treatment of low-risk cesarean scar pregnancy (CSP) was monitored by contrast-enhanced ultrasound (CEUS). Methods. Data were collected from 23 CSP patients with a 10-point risk score <5 (low-risk CSP) and from 23 intrauterine pregnancy (IUP) patients with a scar from a previous cesarean delivery. All patients were prescribed 75 mg mifepristone daily for 2 days and underwent transvaginal CEUS before and after administration of mifepristone. On the third day, uterine curettage was performed after transvaginal CEUS. Arrival time (AT), peak intensity (PI), and area under the curve (AUC) around the gestational sac were monitored by CEUS before and after application of mifepristone, and the rate of effective treatment was compared between the two patient groups. Results. No patients experienced side effects from either the CEUS procedure or the mifepristone treatment. Changes in AT, PI, and AUC index from before vs. after mifepristone treatment did not differ significantly between the two groups (all p values >0.05). There was also no significant difference in the rate of effective treatment between the two groups (95.65% in the CSP group vs. 100% in the IUP group; p > 0.05 ). Conclusions. Based on monitoring by CEUS, the effect of mifepristone in low-risk CSP was comparable to that in IUP.

Contrast-enhanced ultrasound evaluation of the renal microcirculation response to terlipressin in hepato-renal syndrome: a preliminary report

Renal Failure ◽  
2014 ◽  
Vol 37 (1) ◽  
pp. 175-179 ◽  
Author(s):  
Antoine G. Schneider ◽  
Anthony Schelleman ◽  
Mark D. Goodwin ◽  
Michael Bailey ◽  
Glenn M. Eastwood ◽  
...  
Keyword(s):  
Preliminary Report ◽  
Contrast Enhanced Ultrasound ◽  
Renal Microcirculation ◽  
Ultrasound Evaluation ◽  
Contrast Enhanced

Percutaneous removal of sentinel lymph nodes in a swine model using a breast lesion excision system and contrast-enhanced ultrasound

2011 ◽  
Vol 22 (3) ◽  
pp. 545-550 ◽  
Author(s):  
Ali R. Sever ◽  
Philippa Mills ◽  
Jean-Marc Hyvelin ◽  
Jennifer Weeks ◽  
Hatice Gumus ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Breast Lesion ◽  
Sentinel Lymph Nodes ◽  
Swine Model ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Percutaneous Removal

scholarly journals Contrast-enhanced ultrasound evaluation of testicular interstitial cell tumours in conscious non-sedated dogs

2018 ◽  
Vol 63 (No. 3) ◽  
pp. 125-130 ◽  
Author(s):  
M. Quartuccio ◽  
C. Mangano ◽  
F. Macri ◽  
M. Rizzo ◽  
S. Di Pietro ◽  
...  
Keyword(s):  
Interstitial Cell ◽  
Regional Blood Flow ◽  
Mean Transit Time ◽  
Cell Tumour ◽  
Surrounding Tissue ◽  
Histological Evaluation ◽  
Single Type ◽  
Contrast Enhanced Ultrasound ◽  
Ultrasound Evaluation ◽  
Contrast Enhanced

Testicular tumours are the most common neoplasms of the genital system in male dogs. The three main types reported in dogs are interstitial cell tumour, seminoma and Sertoli cell tumour. Interstitial cell tumour is related to the presence of single or multiple nodules inside the testicular parenchyma, and it is detected by palpation or is often an incidental finding during ultrasonography examination. Contrast-enhanced ultrasound allows characterisation of the perfusion of the testicular lesion and reveals the micro-vascularisation; however, perfusion parameters may be strongly influenced by sedative drug administration, so our aim was to evaluate qualitative and quantitative perfusion of a single type of tumour (interstitial cell tumour) with contrast-enhanced ultrasound in conscious dogs to exclude any influence of pharmacological agents on vascular flow. Thirty dogs with focal testicular lesions found by palpation and/or by ultrasound (B-mode and Doppler) examination were selected; contrast-enhanced ultrasound was performed only in subjects that presented testicular focal lesions. After orchiectomy, testes were submitted to histological evaluation; 2-minute clips recorded during contrast-enhanced ultrasound were analysed only in the case of dogs with interstitial cell tumours (n = 12). Contrast medium showed wash-in at around 25–30 seconds, at the same time as the surrounding tissue: lesions were hyperenhancing, homogeneous or inhomogeneous with rim enhancement and contained prominent inner vessels; however, enhancement of small regions was absent. Quantitative analysis demonstrated significantly higher PI% (P = 0.005), regional blood volume (P = 0.02) and regional blood flow (P = 0.007) values in lesions than in surrounding tissue; no differences were found for time-to-peak and mean transit time. In conclusion, the contrast-enhanced ultrasound pattern observed in conscious non-sedated dogs with interstitial cell tumour was similar to the pattern described in a previous study in dogs after intramuscular administration of medetomidine (10 µg/kg) and butorphanol (0.2 mg/kg).

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