LIONS: Analysis Suite for Detecting and Quantifying Transposable Element Initiated Transcription from RNA-seq
Keyword(s):
Rna Seq
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AbstractSummaryTransposable Elements (TEs) influence the evolution of novel transcriptional networks yet the specific and meaningful interpretation of how TE-initiation events contribute to the transcriptome has been marred by computational and methodological deficiencies. We developed LIONS for the analysis of paired-end RNA-seq data to specifically detect and quantify TE-initiated transcripts.AvailabilitySource code, container, test data and instruction manual are freely available at www.github.com/ababaian/[email protected] or [email protected] or [email protected] informationSupplementary data are available at Bioinformatics online.