scholarly journals Semantic Segmentation to Extract Coronary Arteries in Fluoroscopy Angiograms

2020 ◽  
Author(s):  
Chen Zhao ◽  
Haipeng Tang ◽  
Jinshan Tang ◽  
Chaoyang Zhang ◽  
Zhuo He ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Left Coronary Artery ◽  
Semantic Segmentation ◽  
Morphological Similarity ◽  
Vascular Tree ◽  
Vessel Segment ◽  
Different Types ◽  
Feature Pyramid ◽  
Artery Disease ◽  
The Individual

Coronary artery disease (CAD) is the leading cause of death worldwide, constituting more than one-fourth of global mortalities every year. Accurate semantic segmentation of each artery in fluoroscopy angiograms is important for assessment of the stenosis and CAD diagnosis and treatment. However, due to the morphological similarity among different types of arteries, it is hard for deep-learning-based models to generate semantic segmentation with an end-toend approach. In this paper, we propose a multi-step semantic segmentation algorithm based on the analysis of graphs extracted from fluoroscopy angiograms. The proposed algorithm firstly extracts the entire arterial binary mask (binary vascular tree) by Feature Pyramid U-Net++. Then we extract the centerline of the binary vascular tree and separate it into different vessel segments. Finally, by extracting the underlying arterial topology, position and pixel features, we construct a powerful coronary artery classifier based on random forest. Each vessel segment is classified into left coronary artery (LCA), left anterior descending (LAD) and other types of arterial segments. We tested the proposed method on a dataset with 69 LAO and 103 RAO fluoroscopic angiograms and achieved classification accuracies of 66.4% and 61.49% respectively. The experimental results show the effectiveness of the proposed algorithm, which can be used to analyze the individual arteries in fluoroscopy angiograms.

Coronary response to diving in subjects with mild and severe left coronary artery disease

1992 ◽  
Vol 13 (3) ◽  
pp. 299-303 ◽  
Author(s):  
A. SAINO ◽  
P. ALESSIO ◽  
L. GREGORINI ◽  
G. POMIDOSSI ◽  
A. RIMINI ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Left Coronary Artery ◽  
Artery Disease

Abstract 2870: In Women without Obstructive Coronary Artery Disease, Endothelial-Dependent and Non-Endothelial Dependent Coronary Reactivity Dysfunction are Associated with Different Types of Adverse Outcomes. The NHLBI Women’s Ischemia Syndrome Evaluation (WISE).

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Scott Midwall ◽  
R. David Anderson ◽  
Delia Johnson ◽  
Eileen Handberg ◽  
Rhonda Cooper-Dehoff ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Adverse Events ◽  
Obstructive Coronary Artery Disease ◽  
Treatment Strategies ◽  
Adverse Outcomes ◽  
Flow Reserve ◽  
Different Types ◽  
Artery Disease ◽  
Major Adverse Events

Backround: Altered coronary reactivity frequently occurs in women with chest discomfort both with and without obstructive coronary artery disease (CAD). Among those with obstructive CAD, the endothelial-dependent and non-endothelial dependent components of this altered reactivity have been associated with adverse outcomes. The clinical events among those with altered coronary reactivity but without obstructive CAD are not well defined. Methods: We evaluated 169 women with suspected myocardial ischemia who had no obstructive CAD at coronary angiography. Coronary reactivity was assessed by measuring flow reserve (CFR) with adenosine (endothelial-dependent) and change in vessel diameter (DIAM) following acetylcholine (non-endothelial dependent). Women were then followed for major adverse events (death, myocardial infarction, stroke, or hospitalization for heart failure) as well as hospitalization for recurrent angina by annual telephone contact over a median of 6.0 years. Results: Mean age was 54 ± 10 years, 15% were non-white, 37% had abnormal CFR (<2.32), and 47% had abnormal DIAM (no change or constriction). Of the women receiving both coronary reactivity tests, results were concordant in only 52%. Major events occurred in 16% (28/169) of which 5% (8/169) died. An additional 24% (41/169) were hospitalized for worsening angina. Major adverse events were predicted by abnormal CFR (27% vs 10%, p = 0.006) but not abnormal DIAM, while abnormal DIAM, but not CFR, predicted hospitalization for angina. Conclusion: Endothelial-dependent and non-dependent coronary dysfunction coexist in approximately one-half of women tested without angiographic evidence of CAD and appear to predict different types of adverse outcomes during follow-up. These results should foster developement of new diagnostic and treatment strategies targeting both endothelial and non-endothelial (e.g. vascular smooth muscle) dependent coronary dysfunction in women.

scholarly journals Ankylosing Spondyloarthritis Resulting Severe Aortic Insufficiency and Aortitis: Exacerbation of Ankylosing Spondyloarthritis and Stenosis of the Main Left Coronary Artery after Mechanical Aortic Valve Implantation with Cardiopulmonary Bypass

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Agnė Balčiūnaitė ◽  
Algimantas Budrikis ◽  
Eglė Rumbinaitė ◽  
Jurgita Sabaliauskienė ◽  
Vaiva Patamsytė ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Coronary Artery ◽  
Aortic Valve ◽  
Left Coronary Artery ◽  
Human Leukocyte ◽  
Aortic Insufficiency ◽  
Severe Aortic Regurgitation ◽  
Before And After ◽  
Artery Disease ◽  
Ankylosing Spondyloarthritis

Ankylosing spondyloarthritis (AS) is a chronic inflammatory rheumatic disease, strongly related to human leukocyte antigen (HLA)-B27. Cardiac involvement in AS manifests in 2 to 10% of patients as aortic insufficiency, aortitis, mitral valve fibrosis, or disturbance in the conduction of the heart. In this article, we present a case of a 49-year-old male patient with AS, who was referred to our medical institution for elective aortic valve surgery because of severe aortic regurgitation. The histological findings revealed fibrosing endocarditis of aortic valve and nonspecific aortitis of aortic root. Late postoperatively, we observed exacerbation of AS and narrowing of the main left coronary artery (LAD). Our case highlights the importance of proper treatment of AS before and after cardiac surgery. Furthermore, in this case, we suspect association between cardiopulmonary bypass, activity of AS, and coronary artery disease.

Limitations of exercise testing in critical left coronary artery disease

1979 ◽  
Vol 12 (3) ◽  
pp. 241-248 ◽  
Author(s):  
Gerald C. Timmis ◽  
Douglas C. Westveer ◽  
Seymour Gordon ◽  
Renato G. Ramos ◽  
V. Gangadharan
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Exercise Testing ◽  
Left Coronary Artery ◽  
Artery Disease

The diagnostic inadequacy of exercise testing in critical left coronary artery disease

1977 ◽  
Vol 10 (4) ◽  
pp. 321-330 ◽  
Author(s):  
Gerald G. Timmis ◽  
Seymour Gordon ◽  
Renato G. Ramos ◽  
V. Gangadharan
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Exercise Testing ◽  
Left Coronary Artery ◽  
Artery Disease
Sign in / Sign up

Export Citation Format

Share Document