scholarly journals AUTISM SPECTRUM DISORDER: A POSSIBLE LINK WITH CHONDROITIN SULFATE

2020 ◽  
Author(s):  
Eduardo Listik ◽  
Marcia Listik ◽  
Clarice Listik ◽  
Leny Toma
Keyword(s):  
Autism Spectrum Disorder ◽  
Healthy Volunteers ◽  
Chondroitin Sulfate ◽  
Low Cost ◽  
Autism Spectrum ◽  
Clinical Aspect ◽  
Spectrum Disorder ◽  
Autism Behavior Checklist ◽  
Autism Behavior

ABSTRACTThis study aimed to determine discrepancies in the urinary glycosaminoglycan profiles of autism spectrum disorder (ASD) patients (n=9) when compared with those from healthy volunteers (HVs, n=3). The guardians and/or educators for each participant also returned a validated Autism Behavior Checklist (ABC). The urinary chondroitin sulfate (CS) concentration was 46.1% lower in the ASD group than in the HV group. The ABC score and the urinary CS concentration were negatively correlated (Spearman’s ρ=– 0.2635), indicating that as the severity of the clinical aspect of this disorder increased, the urinary CS concentration decreased. These results suggest that low CS concentrations in the urine may be associated with ASD, and could be measured using a fast and low-cost method for diagnostics.

Procedures and compliance of a video modeling applied behavior analysis intervention for Brazilian parents of children with autism spectrum disorders

Autism ◽  
2017 ◽  
Vol 21 (5) ◽  
pp. 603-610 ◽  
Author(s):  
Leila F Bagaiolo ◽  
Jair de J Mari ◽  
Daniela Bordini ◽  
Tatiane C Ribeiro ◽  
Maria Carolina C Martone ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Applied Behavior Analysis ◽  
Joint Attention ◽  
Video Modeling ◽  
Low Cost ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Training Intervention ◽  
Parental Training

Video modeling using applied behavior analysis techniques is one of the most promising and cost-effective ways to improve social skills for parents with autism spectrum disorder children. The main objectives were: (1) To elaborate/describe videos to improve eye contact and joint attention, and to decrease disruptive behaviors of autism spectrum disorder children, (2) to describe a low-cost parental training intervention, and (3) to assess participant’s compliance. This is a descriptive study of a clinical trial for autism spectrum disorder children. The parental training intervention was delivered over 22 weeks based on video modeling. Parents with at least 8 years of schooling with an autism spectrum disorder child between 3 and 6 years old with an IQ lower than 70 were invited to participate. A total of 67 parents fulfilled the study criteria and were randomized into two groups: 34 as the intervention and 33 as controls. In all, 14 videos were recorded covering management of disruptive behaviors, prompting hierarchy, preference assessment, and acquisition of better eye contact and joint attention. Compliance varied as follows: good 32.4%, reasonable 38.2%, low 5.9%, and 23.5% with no compliance. Video modeling parental training seems a promising, feasible, and low-cost way to deliver care for children with autism spectrum disorder, particularly for populations with scarce treatment resources.

Lessons learned while developing, adapting and implementing a pilot parent-mediated behavioural intervention for children with autism spectrum disorder in rural Bangladesh

Autism ◽  
2017 ◽  
Vol 21 (5) ◽  
pp. 611-621 ◽  
Author(s):  
Jasmine M Blake ◽  
Eric Rubenstein ◽  
Peng-Chou Tsai ◽  
Hafizur Rahman ◽  
Sarah R Rieth ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Low Cost ◽  
Autism Spectrum ◽  
Lessons Learned ◽  
Spectrum Disorder ◽  
Behavioural Intervention ◽  
Middle Income ◽  
Rural Bangladesh ◽  
Native Child ◽  
Behavioural Strategies

Low- and middle-income countries often have limited resources, underdeveloped health systems and scarce knowledge of autism spectrum disorder. The objectives of this preliminary study were to develop and adapt intervention materials and to train a native clinician to implement a community-based parent-mediated behavioural intervention in rural Gaibandha, Bangladesh. Intervention materials to support parents’ use of behavioural strategies were developed and refined by US behavioural intervention experts and Bangladesh field experts. Study investigators trained a native child psychologist in developmental milestones and behavioural intervention techniques. The native clinician delivered a 1-day group education session attended by 10 families of children aged 7–9 years with autism spectrum disorder, followed by two one-on-one training sessions with each family to train and practice individualized strategies for targeted challenging behaviours. Preliminary qualitative results indicate the importance of materials that are culturally appropriate and at an adequate literacy level. All families expressed strong desires to have learned the behavioural strategies when their child was younger and vocalized their need for further support and tools to help their children. This study is a preliminary step to creating sustainable and low-cost autism spectrum disorder interventions in rural Bangladesh, and possibly for families in regions with similar cultural and socioeconomic status backgrounds.

177. Autism Behavior Inventory – A Novel Tool for Assessment of Changes in Core and Associated Symptoms of Autism Spectrum Disorder

2017 ◽  
Vol 81 (10) ◽  
pp. S73-S74
Author(s):  
Abigail Bangerter ◽  
Seth Ness ◽  
David Lewin ◽  
Michael Aman ◽  
Anna Esbensen ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Associated Symptoms ◽  
Autism Behavior

scholarly journals Autism Behavior Inventory: A Novel Tool for Assessing Core and Associated Symptoms of Autism Spectrum Disorder

2017 ◽  
Vol 27 (9) ◽  
pp. 814-822 ◽  
Author(s):  
Abi Bangerter ◽  
Seth Ness ◽  
Michael G. Aman ◽  
Anna J. Esbensen ◽  
Matthew S. Goodwin ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Associated Symptoms ◽  
Autism Behavior

Randomized pilot study of a special education advocacy program for Latinx/minority parents of children with autism spectrum disorder

Autism ◽  
2021 ◽  
pp. 136236132199856
Author(s):  
Paul Luelmo ◽  
Connie Kasari ◽  
Keyword(s):  
Autism Spectrum Disorder ◽  
Special Education ◽  
Low Income ◽  
Low Cost ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Parent Advocacy ◽  
Low Intensity ◽  
Racial Ethnic

This study reports on a randomized controlled pilot intervention study examining the effectiveness and feasibility of a low-intensity (i.e. three sessions), low-cost, parent advocacy intervention. The intervention study employed community-partnered research methods and targeted a low-income community of mostly Latinx, immigrant-origin parents of children with autism spectrum disorder. The study was designed to test a parent-to-parent advocacy mentorship program in order to increase parent’s special education advocacy knowledge and empowerment. The educational intervention was delivered in Spanish to Spanish-speaking parents. Results indicated significantly increased in parent’s knowledge in the immediate intervention group, but this knowledge did not lead to greater sense of parent’s empowerment. Increases in knowledge about special education rights of their children are the first step toward advocating for services for their children. While parents from low-income, racial/ethnic minority backgrounds, particularly Latinx parents, can significantly increase their advocacy skills with a low-intensity, low-cost program, they may need more support in changing their self-perceptions of empowerment and advocacy. Lay abstract Persistent racial and ethnic disparities in obtaining an autism spectrum disorder diagnosis and services have been documented for Latinx children and other racial/ethnic minorities. This study reports on an educational intervention examining the effectiveness and feasibility of a low-intensity (i.e. three sessions), low-cost, parent advocacy for Latinx and other minority parents of children with autism. Results indicated significantly increased parental knowledge and in the immediate intervention group, but this knowledge did not lead to greater empowerment. While parents from low-income, racial/ethnic minority backgrounds, particularly Latinx parents, can significantly increase their advocacy skills with a low-intensity, low-cost program, they may need more support in changing their self-perceptions of empowerment and advocacy.

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