Characterization of spectral diffusion by slow-light photon-correlation spectroscopy

2020 ◽  
Vol 101 (16) ◽  
Author(s):  
H. Vural ◽  
J. Maisch ◽  
I. Gerhardt ◽  
M. Jetter ◽  
S. L. Portalupi ◽  
...  
1979 ◽  
Vol 34 (1) ◽  
pp. 68-75 ◽  
Author(s):  
E. Killmann ◽  
J. Eisenlauer ◽  
P. Kaniut

Abstract The diffusion of silica(Aerosil)-hydrosols has been studied by photon correlation spectroscopy. For data analysis the method of cumulants, proposed by Koppel, was used. Effects of charge and hydratation of the silica particles and their complicated aggregated structure required an extrapolation to the solconcentration cs = 0 and the scattering angle θ = 0.The described data analysis combined with the methodical proceeding - using Aerosil aggregates as a model system - shows how to evaluate the diffusion coefficient and its normalized variance. These data of characterization are important for many kinds of aggregated particles in technical applied dispersions.


2011 ◽  
Vol 236-238 ◽  
pp. 2917-2920 ◽  
Author(s):  
Jia Ying Wu ◽  
Qiang Xia

To function lipophilic drug Azithromycin (AZM) as ophthalmic preparation, Azithromycin-loaded Nanostructured Lipid Carriers (AZM-NLC) were prepared by High Pressure Homogenization (HPH), and its stability was analyzed afterwards. Well-dissolved lipids of Azithromycin were selected, how the ratio of surfactants to lipids influenced the preparation of AZM-NLC was studied, and mature surfactant system was chosen. The optimized ratio of lipid carriers to emulsifiers [ polyoxyethylene (40) stearate - Poloxamer188 (7:3)] in this study was 1:6, and the final drug-capacity rate was 0.5%. Obtained by photon correlation spectroscopy, the mean particle size of AZM-NLC was 76±2 nm. The results showed that AZM-NLC had kept stable for 15 days, and mean particle size increased to 83 nm after four months.


Sign in / Sign up

Export Citation Format

Share Document