This talk consists of two parts. In part I we review how the minimal renormalizable supersymmetric SO (10) model, an SO (10) framework with only one 10 and one [Formula: see text] Higgs multiplets in the Yukawa sector, is attractive because of its highly predictive power. Indeed it not only gives a consistent predictions on neutrino oscillation data but also gives reasonable and interesting values for leptogenesis, LFV, muon g - 2, neutrinoless double beta decay etc. However, this model suffers from problems related to running of gauge couplings. The gauge coupling unification may be spoiled due to the presence of Higgs multiplets much lighter than the grand unification (GUT) scale. In addition, the gauge couplings blow up around the GUT scale because of the presence of Higgs multiplets of large representations. In part II we consider the minimal SO (10) model in the warped extra dimension and show a possibility to solve these problems.