Crystal structure of a nucleoside model for the interstrand cross-link formed by the reaction of 2′-deoxyguanosine and an abasic site in duplex DNA
2016 ◽
Vol 72
(5)
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pp. 624-627
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Keyword(s):
The title compound, 9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-{[(2R,4S,5R)-4-methoxy-5-(methoxymethyl)tetrahydrofuran-2-yl]amino}-1H-purin-6(9H)-one, C17H25N5O7, crystallizes with two independent molecules (AandB) in the asymmetric unit. In the crystal, the guanosine moieties of moleculesAandBare linked by N—H...N and O—H...N hydrogen-bonding interactions, forming ribbons which are stacked to form columns along [100]. These columns are then linked by O—H...O hydrogen bonds between the ribose moieties and numerous C—H...O interactions to complete the three-dimensional structure.
2014 ◽
Vol 70
(11)
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pp. 322-324
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Keyword(s):
2014 ◽
Vol 70
(11)
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pp. 418-420
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2015 ◽
Vol 71
(2)
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pp. o123-o124
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2015 ◽
Vol 71
(12)
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pp. o1063-o1064
Keyword(s):
2016 ◽
Vol 72
(8)
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pp. 1077-1080
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2016 ◽
Vol 72
(4)
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pp. 463-466
2019 ◽
Vol 75
(2)
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pp. 299-303
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2015 ◽
Vol 71
(3)
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pp. o171-o172