Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}-N-phenylacetamide
2021 ◽
Vol 77
(6)
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pp. 663-667
Keyword(s):
The Mean
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The title molecule, C29H29N3O4S, adopts a conformation with the two phenyl substituents disposed on opposite sides of the mean plane of the isoquinoline unit. In the crystal, corrugated layers of molecules are formed by N—H...O, C—H...N and C—H...S hydrogen bonds together with C—H...π(ring) interactions. These layers are connected by C—H...O contacts. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H...H (45.2%), C...H/H...C (20.2%), O...H/H...O (15.8%) and N...H/H...N (11.0%) interactions.
2021 ◽
Vol 77
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pp. 730-733
2019 ◽
Vol 75
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pp. 638-641
2019 ◽
Vol 75
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pp. 237-241
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Keyword(s):
2021 ◽
Vol 77
(6)
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pp. 643-646
Keyword(s):
2019 ◽
Vol 75
(1)
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pp. 81-85
2019 ◽
Vol 75
(6)
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pp. 721-727
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2021 ◽
Vol 77
(6)
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pp. 672-676
2021 ◽
Vol 77
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pp. 356-359
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