scholarly journals Quantitative Reconstruction of Dual K-Edge Contrast Agent Distribution for Photon- Counting Computed Tomography

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 124441-124451 ◽  
Author(s):  
Xiaotong Zhang ◽  
Dayu Xiao ◽  
Yan Kang
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Petri Paakkari ◽  
Satu I. Inkinen ◽  
Miitu K. M. Honkanen ◽  
Mithilesh Prakash ◽  
Rubina Shaikh ◽  
...  

AbstractPhoton-counting detector computed tomography (PCD-CT) is a modern spectral imaging technique utilizing photon-counting detectors (PCDs). PCDs detect individual photons and classify them into fixed energy bins, thus enabling energy selective imaging, contrary to energy integrating detectors that detects and sums the total energy from all photons during acquisition. The structure and composition of the articular cartilage cannot be detected with native CT imaging but can be assessed using contrast-enhancement. Spectral imaging allows simultaneous decomposition of multiple contrast agents, which can be used to target and highlight discrete cartilage properties. Here we report, for the first time, the use of PCD-CT to quantify a cationic iodinated CA4+ (targeting proteoglycans) and a non-ionic gadolinium-based gadoteridol (reflecting water content) contrast agents inside human osteochondral tissue (n = 53). We performed PCD-CT scanning at diffusion equilibrium and compared the results against reference data of biomechanical and optical density measurements, and Mankin scoring. PCD-CT enables simultaneous quantification of the two contrast agent concentrations inside cartilage and the results correlate with the structural and functional reference parameters. With improved soft tissue contrast and assessment of proteoglycan and water contents, PCD-CT with the dual contrast agent method is of potential use for the detection and monitoring of osteoarthritis.


2017 ◽  
Vol 25 (8) ◽  
pp. 9378 ◽  
Author(s):  
Bo Meng ◽  
Wenxiang Cong ◽  
Yan Xi ◽  
Bruno De Man ◽  
Jian Yang ◽  
...  

2020 ◽  
Vol 8 (20) ◽  
pp. 5715-5728
Author(s):  
Joëlle Balegamire ◽  
Marc Vandamme ◽  
Emmanuel Chereul ◽  
Salim Si-Mohamed ◽  
Samira Azzouz Maache ◽  
...  

Suspensions of iodinated polymer nanoparticles are evaluated as contrast agent for Computed Tomography (CT) and Spectral Photon Counting Computed Tomography (SPCCT).


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Salim Si-Mohamed ◽  
Valérie Tatard-Leitman ◽  
Alexis Laugerette ◽  
Monica Sigovan ◽  
Daniela Pfeiffer ◽  
...  

2018 ◽  
Vol 53 (10) ◽  
pp. 629-639 ◽  
Author(s):  
Salim Si-Mohamed ◽  
Arnaud Thivolet ◽  
Pierre-Emmanuel Bonnot ◽  
Daniel Bar-Ness ◽  
Vahan Képénékian ◽  
...  

2017 ◽  
Vol 33 (8) ◽  
pp. 1253-1261 ◽  
Author(s):  
Rolf Symons ◽  
Tyler E. Cork ◽  
Manu N. Lakshmanan ◽  
Robert Evers ◽  
Cynthia Davies-Venn ◽  
...  

Author(s):  
Erdem Yilmaz ◽  
Osman Kostek ◽  
Savas Hereklioglu ◽  
Muhammet Goktas ◽  
Nermin Tuncbilek

Aims: To demonstrate the prevalence, accompanying pathologies, imaging and follow up findings of Duodenal Diverticula (DD) with Multidetector Computed Tomography (MDCT). Materials and Methods: Consecutive 2910 abdominal MDCTs were retrospectively reviewed on axial, coronal and sagittal planes. DD were evaluated for prevalence, location, number, size, contents, diverticular neck, accompanying pancreaticobiliary pathologies, jejunal and colonic diverticula, respectively. Results: DD were diagnosed in 157 cases (5.4%) and found mostly in the second part of the duodenum. Juxta-ampullary DD was the most common type (78.3%) and mostly located ventral (n:86, 69.9%) to the ampulla of Vater. DD was solitary in 123 patients (78.3%) and more than one in 34 patients (21.7%). The median diameter of DD was 2.5 cm (range 1.5-3.6 cm) in the long-axis. The lumen of DD contains air and contrast agent (n:96, 61.1%); air, contrast agent and debris (n:42, 26.7%) in most cases. Colonic diverticula (n:36, 22.9%), cholelithiasis (n:32, 20.4%), choledocholithiasis (n:7, 4.4%), and biliary dilatation (n:8, 5.1%) were the most common additional findings. Median follow-up time was 23 months (range 11 to 41 months). In three cases, new findings (cholelithiasis, n:3, choledocholithiasis, n:1) were detected. Conclusion: Accompanying pathologies with DD diagnosis are valuable for physicians in order to manage the patients. Following clinical and radiological features of well-diagnosed DD might reduce the possible complications.


2015 ◽  
Author(s):  
Z. Yu ◽  
S. Leng ◽  
S. M. Jorgensen ◽  
Z. Li ◽  
R. Gutjahr ◽  
...  

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