scholarly journals Towards Change Propagating Test Models in Autonomic and Adaptive Systems

Author(s):  
Mohammed Akour ◽  
Akanksha Jaidev ◽  
Tariq M. King
Keyword(s):  

1992 ◽  
Vol 67 (06) ◽  
pp. 660-664 ◽  
Author(s):  
Virgilio Evangelista ◽  
Paola Piccardoni ◽  
Giovanni de Gaetano ◽  
Chiara Cerletti

SummaryDefibrotide is a polydeoxyribonucleotide with antithrombotic effects in experimental animal models. Most of the actions of this drug have been observed in in vivo test models but no effects have been reported in in vitro systems. In this paper we demonstrate that defibrotide interferes with polymorphonuclear leukocyte-induced human platelet activation in vitro. This effect was not related to any direct interaction with polymorphonuclear leukocytes or platelets, but was due to the inhibition of cathepsin G, the main biochemical mediator of this cell-cell cooperation. Since cathepsin G not only induces platelet activation but also affects some endothelial cell functions, the anticathepsin G activity of defibrotide could help to explain the antithrombotic effect of this drug.





2013 ◽  
Vol 12 (3) ◽  
Author(s):  
Iskendar Iskendar ◽  
Andi Jamaludin ◽  
Paulus Indiyono

This paper describes hydrodynamic model tests of Wing in Surface Effect (WiSE) Craft. These craft  was fitted with  stephull  form in different location on longitudinal flat bottom (stepedhull planning craft) to determine the influences of sticking and porpoising motion performances. These motions are usually occured when the craft start to take-off from water surfaces. The test models with scale of 1 : 7 were comprised of 4 (four) stephull models and 1 (one) non-stephull model  as a comparative study. The hydrodynamic  tests were performed with craft speed of 16 – 32 knots (prototype values) in Towing Tank at UPT. Balai Pengkajian dan Penelitian Hidrodinamika (BPPH), BPPT, Surabaya. The resistance (drag) was measured by dynamo meter and the trim of model (draft changing at fore and aft  of model due to model speed) was measured by trim meter. By knowing the value of model trim, the wetted surface area can be determined. Then, the lift forces were calculated based on these measured values. The model test results were presented on tables and curves.  Test results show that models  with step located far away from center of gravity of the WiSE craft tend to porpoising and sticking condition, except if the step location on the below of these center of gravity. While model without step tends to sticking conditions.



Author(s):  
O. P. Tomchina ◽  
D. N. Polyakhov ◽  
O. I. Tokareva ◽  
A. L. Fradkov

Introduction: The motion of many real world systems is described by essentially non-linear and non-stationary models. A number of approaches to the control of such plants are based on constructing an internal model of non-stationarity. However, the non-stationarity model parameters can vary widely, leading to more errors. It is only assumed in this paper that the change rate of the object parameters is limited, while the initial uncertainty can be quite large.Purpose: Analysis of adaptive control algorithms for non-linear and time-varying systems with an explicit reference model, synthesized by the speed gradient method.Results: An estimate was obtained for the maximum deviation of a closed-loop system solution from the reference model solution. It is shown that with sufficiently slow changes in the parameters and a small initial uncertainty, the limit error in the system can be made arbitrarily small. Systems designed by the direct approach and systems based on the identification approach are both considered. The procedures for the synthesis of an adaptive regulator and analysis of the synthesized system are illustrated by an example.Practical relevance: The obtained results allow us to build and analyze a broad class of adaptive systems with reference models under non-stationary conditions.



2011 ◽  
Vol 30 (10) ◽  
pp. 2442-2445
Author(s):  
Jun Sun ◽  
Dong-feng Yuan


2006 ◽  
Author(s):  
Timothy E. Busch ◽  
Dawn A. Trevisani




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