Modularity in design: A review

2015 ◽  
Author(s):  
Rajasaheb Vasawade ◽  
Bhagyesh Deshmukh ◽  
Vijay Kulkarni
Keyword(s):  
Modularity In Design

A method for modularity in design rules for additive manufacturing

2017 ◽  
Vol 23 (6) ◽  
pp. 1107-1118 ◽  
Author(s):  
Haeseong Jee ◽  
Paul Witherell
Keyword(s):  
Additive Manufacturing ◽  
Design Methodology ◽  
Explicit Representation ◽  
Modular Representations ◽  
Specific Context ◽  
Design Rules ◽  
Content Type ◽  
Specific Process ◽  
Modularity In Design

Purpose As the technology matures, design rules for additive manufacturing (AM) can help ensure manufacturability, which can be viewed as compatibility between designs and the fabrication processes that produce those designs. Though often informal, current rules frequently provide direct guidelines or constraints for designing AM-destined parts. The aim of this paper is to standardize how design rules are developed and conveyed in AM by presenting design rules as sets of modular components and associated formalisms. Design/methodology/approach The proposed methodology decomposes fundamental geometry, process and material relationships into reusable modules. Independent of context, modular representations can be more easily interpreted and efficiently implemented than current one. By providing task-specific context, components are specialized to represent process-specific parameters for different AM builds and processes. This method of specialization enables designers to reconfigure design rules, rather than create new rules from scratch, thus preserving fundamental AM principles while supporting customization and explicit representation. Findings Modularity and formalisms provide both structure for the generalizations and a means to tailor that structure for a specific process, machine or build. The adoption of principles and formalisms that allow us to modify, extend, reconfigure or customize generalized rules as needed – instinctively and deliberately. Originality/value This method of specialization enables designers to reconfigure design rules, rather than create new rules from scratch, thus preserving fundamental AM principles while supporting customization and explicit representation.

scholarly journals Modularity-in-Design of Dynamical Network Systems: Retrofit Control Approach

2020 ◽  
pp. 1-1
Author(s):  
Takayuki Ishizaki ◽  
Hampei Sasahara ◽  
Masaki Inoue ◽  
Takahiro Kawaguchi ◽  
Jun-ichi Imura
Keyword(s):  
Network Systems ◽  
Control Approach ◽  
Dynamical Network ◽  
Modularity In Design

scholarly journals Hybrid Data Acquisition and Analysis System for Flowing Medium Lasers

2020 ◽  
Vol 70 (3) ◽  
pp. 285-291
Author(s):  
Rajeev K. Dohare ◽  
Mainuddin Siddique ◽  
Gaurav Singhal
Keyword(s):  
Data Acquisition ◽  
Real Time ◽  
Laser Source ◽  
Gas Lasers ◽  
Complex Processes ◽  
Lasing Medium ◽  
Hybrid Data ◽  
Remote System ◽  
Analysis System ◽  
Modularity In Design

The medium gas lasers involves in-situ generation of the lasing medium, hence are associated with several complex processes including mixing of pumping and lasing species, energy exchange between the species, heat generation during reaction and its influence on the flow domain to list a few. Thus, the characterisation of lasing medium, condition of operation of individual critical subsystems and corresponding phenomenon thereof is essential in real time. It is here that a customised data acquisition and analysis system (DAAS) plays a key role. The paper dwells on the realisation of a customised hybrid DAAS with a master-slave architecture, which is portable and provides remote system operation. The noteworthy aspects of the developed DAAS include capability to handle close to 150 channels [64 analog input, 64 digital output, 5 analog output and 17 digital input] simultaneously with varied sampling rates requirement ranging from 100 samples/s to 200 k samples/s, modularity in design enabling scalability. Further, the efficacy of the developed DAAS has been tested by conducting several real time experiments with an existing chemical oxygen iodine laser source with a mass flow rate of 2.3 moles.s-1 both from close ranges and at line of sight remote distances of up to 80 m and nearly 35 m with obstacles.

scholarly journals A compact synthetic pathway rewires cancer signaling to therapeutic effector release

Science ◽  
2019 ◽  
Vol 364 (6439) ◽  
pp. eaat6982 ◽  
Author(s):  
Hokyung K. Chung ◽  
Xinzhi Zou ◽  
Bryce T. Bajar ◽  
Veronica R. Brand ◽  
Yunwen Huo ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cancer Detection ◽  
Molecular Medicine ◽  
Erbb Receptor ◽  
Adeno Associated Virus ◽  
Specific Cancer ◽  
New Strategy ◽  
Endogenous Genes ◽  
Induced Apoptosis ◽  
Modularity In Design

An important goal in synthetic biology is to engineer biochemical pathways to address unsolved biomedical problems. One long-standing problem in molecular medicine is the specific identification and ablation of cancer cells. Here, we describe a method, named Rewiring of Aberrant Signaling to Effector Release (RASER), in which oncogenic ErbB receptor activity, instead of being targeted for inhibition as in existing treatments, is co-opted to trigger therapeutic programs. RASER integrates ErbB activity to specifically link oncogenic states to the execution of desired outputs. A complete mathematical model of RASER and modularity in design enable rational optimization and output programming. Using RASER, we induced apoptosis and CRISPR-Cas9–mediated transcription of endogenous genes specifically in ErbB-hyperactive cancer cells. Delivery of apoptotic RASER by adeno-associated virus selectively ablated ErbB-hyperactive cancer cells while sparing ErbB-normal cells. RASER thus provides a new strategy for oncogene-specific cancer detection and treatment.

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