Flow-Independent Microbubble Isolation by Rapid Recondensation of Phase-Change Nanodrops after Acoustic Droplet Vaporization

2021 ◽  
Author(s):  
Mark T. Burgess ◽  
Jeffrey A. Ketterling ◽  
Mitra Aliabouzar ◽  
Christian Aguilar ◽  
Mario L. Fabiilli
Keyword(s):  
Phase Change ◽  
Acoustic Droplet Vaporization ◽  
Droplet Vaporization

scholarly journals From Micro- to Nano-Multifunctional Theranostic Platform: Effective Ultrasound Imaging Is Not Just a Matter of Scale

2018 ◽  
Vol 17 ◽  
pp. 153601211877821 ◽  
Author(s):  
Sara Zullino ◽  
Monica Argenziano ◽  
Ilaria Stura ◽  
Caterina Guiot ◽  
Roberta Cavalli
Keyword(s):  
Diagnostic Imaging ◽  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging ◽  
Tumor Tissue ◽  
Ultrasound Contrast Agents ◽  
Acoustic Droplet Vaporization ◽  
Droplet Vaporization ◽  
Enhanced Permeability And Retention ◽  
Ultrasound Contrast

Ultrasound Contrast Agents (UCAs) consisting of gas-filled-coated Microbubbles (MBs) with diameters between 1 and 10 µm have been used for a number of decades in diagnostic imaging. In recent years, submicron contrast agents have proven to be a viable alternative to MBs for ultrasound (US)-based applications for their capability to extravasate and accumulate in the tumor tissue via the enhanced permeability and retention effect. After a short overview of the more recent approaches to ultrasound-mediated imaging and therapeutics at the nanoscale, phase-change contrast agents (PCCAs), which can be phase-transitioned into highly echogenic MBs by means of US, are here presented. The phenomenon of acoustic droplet vaporization (ADV) to produce bubbles is widely investigated for both imaging and therapeutic applications to develop promising theranostic platforms.

Acoustic droplet vaporization for the enhancement of ultrasound thermal therapy

2010 ◽  
Author(s):  
Man Zhang ◽  
Mario Fabiilli ◽  
Paul Carson ◽  
Frederic Padilla ◽  
Scott Swanson ◽  
...  
Keyword(s):  
Thermal Therapy ◽  
Acoustic Droplet Vaporization ◽  
Droplet Vaporization

scholarly journals Initial nucleation site formation due to acoustic droplet vaporization

2014 ◽  
Vol 104 (6) ◽  
pp. 063703 ◽  
Author(s):  
David S. Li ◽  
Oliver D. Kripfgans ◽  
Mario L. Fabiilli ◽  
J. Brian Fowlkes ◽  
Joseph L. Bull
Keyword(s):  
Nucleation Site ◽  
Site Formation ◽  
Acoustic Droplet Vaporization ◽  
Droplet Vaporization ◽  
Initial Nucleation
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