The degradation of Alizarin red dye (Anthraquinone) was investigated using a novel technique of strong ionization discharge to generate high oxidation active species from oxygen. Under the optimum conditions, AR dye was almost removed with degradation rate reaching 95%, by radicals such as •OH and O3 generated within the strong ionization discharge reactor. The intermediate products were analyzed by ultraviolet (UV) spectroscopy, total organic carbon (TOC) analysis, liquid chromatography-mass spectrometry (LC-MS) and ion chromatography (IC) to validate the degradation efficiency of the strong ionization discharge for AR dye and to deduce its possible decomposition pathway. Finally, It has been confirmed that the sulfur element on AR molecule results into sulfate, an environmentally friendly substance. This work shows that the strong ionization discharge can efficiently be used for the degradation of Anthraquinone dyes as well as other extensively used textile dyes.