Proof of concept for a chronic, percutaneous, osseointegrated neural interface for bi-directional prosthetic control with haptic feedback*

2019 ◽  
Author(s):  
Aaron M. Dingle ◽  
Jared P. Ness ◽  
Joseph Novello ◽  
Weifeng Zeng ◽  
Augusto X. T. Millevolte ◽  
...  
Keyword(s):  
Haptic Feedback ◽  
Neural Interface ◽  
Proof Of Concept ◽  
Prosthetic Control

scholarly journals Improving the Selectivity of an Osseointegrated Neural Interface: Proof of Concept For Housing Sieve Electrode Arrays in the Medullary Canal of Long Bones

2021 ◽  
Vol 15 ◽  
Author(s):  
Augusto X. T. Millevolte ◽  
Aaron M. Dingle ◽  
Jared P. Ness ◽  
Joseph Novello ◽  
Weifeng Zeng ◽  
...  
Keyword(s):  
Medullary Canal ◽  
Neural Interface ◽  
Proof Of Concept ◽  
Electrode Arrays ◽  
Prosthetic Control ◽  
Cuff Electrode ◽  
Cortical Responses ◽  
The Stability ◽  
And Function ◽  
Working Hypotheses

Sieve electrodes stand poised to deliver the selectivity required for driving advanced prosthetics but are considered inherently invasive and lack the stability required for a chronic solution. This proof of concept experiment investigates the potential for the housing and engagement of a sieve electrode within the medullary canal as part of an osseointegrated neural interface (ONI) for greater selectivity toward improving prosthetic control. The working hypotheses are that (A) the addition of a sieve interface to a cuff electrode housed within the medullary canal of the femur as part of an ONI would be capable of measuring efferent and afferent compound nerve action potentials (CNAPs) through a greater number of channels; (B) that signaling improves over time; and (C) that stimulation at this interface generates measurable cortical somatosensory evoked potentials through a greater number of channels. The modified ONI was tested in a rabbit (n = 1) amputation model over 12 weeks, comparing the sieve component to the cuff, and subsequently compared to historical data. Efferent CNAPs were successfully recorded from the sieve demonstrating physiological improvements in CNAPs between weeks 3 and 5, and somatosensory cortical responses recorded at 12 weeks postoperatively. This demonstrates that sieve electrodes can be housed and function within the medullary canal, demonstrated by improved nerve engagement and distinct cortical sensory feedback. This data presents the conceptual framework for housing more sophisticated sieve electrodes in bone as part of an ONI for improving selectivity with percutaneous connectivity toward improved prosthetic control.

Vision-based haptic feedback for capsule endoscopy navigation: a proof of concept

2016 ◽  
Vol 11 (1-4) ◽  
pp. 35-45 ◽  
Author(s):  
Marco Mura ◽  
Yasmeen Abu-Kheil ◽  
Gastone Ciuti ◽  
Marco Visentini-Scarzanella ◽  
Arianna Menciassi ◽  
...  
Keyword(s):  
Capsule Endoscopy ◽  
Haptic Feedback ◽  
Proof Of Concept

Development of an all-SiC neuronal interface device

MRS Advances ◽  
2016 ◽  
Vol 1 (55) ◽  
pp. 3679-3684 ◽  
Author(s):  
Evans Bernardin ◽  
Christopher L. Frewin ◽  
Abhishek Dey ◽  
Richard Everly ◽  
Jawad Ul Hassan ◽  
...  
Keyword(s):  
Silicon Carbide ◽  
Nervous System ◽  
Microelectrode Array ◽  
Severe Trauma ◽  
Polymer Coatings ◽  
Neural Interface ◽  
Material System ◽  
Proof Of Concept ◽  
Brain Machine Interfaces ◽  
Preliminary Testing

ABSTRACTThe intracortical neural interface (INI) is a key component of brain machine interfaces (BMI) which offer the possibility to restore functions lost by patients due to severe trauma to the central or peripheral nervous system. Unfortunately today’s neural electrodes suffer from a variety of design flaws, mainly the use of non-biocompatible materials based on Si or W with polymer coatings to mask the underlying material. Silicon carbide (SiC) is a semiconductor that has been proven to be highly biocompatible, and this chemically inert, physically robust material system may provide the longevity and reliability needed for the INI community. The design, fabrication, and preliminary testing of a prototype all-SiC planar microelectrode array based on 4H-SiC with an amorphous silicon carbide (a-SiC) insulator is described. The fabrication of the planar microelectrode was performed utilizing a series of conventional micromachining steps. Preliminary data is presented which shows a proof of concept for an all-SiC microelectrode device.

scholarly journals Methodology for creating a chronic osseointegrated neural interface for prosthetic control in rabbits

2020 ◽  
Vol 331 ◽  
pp. 108504 ◽  
Author(s):  
Aaron M. Dingle ◽  
Jared P. Ness ◽  
Joseph Novello ◽  
Jacqueline S. Israel ◽  
Ruston Sanchez ◽  
...  
Keyword(s):  
Neural Interface ◽  
Prosthetic Control

scholarly journals Motor unit drive: a neural interface for real-time upper limb prosthetic control

2018 ◽  
Vol 16 (1) ◽  
pp. 016012 ◽  
Author(s):  
Michael D Twardowski ◽  
Serge H Roy ◽  
Zhi Li ◽  
Paola Contessa ◽  
Gianluca De Luca ◽  
...  
Keyword(s):  
Real Time ◽  
Motor Unit ◽  
Upper Limb ◽  
Neural Interface ◽  
Prosthetic Control

Portable, automated foot progression angle gait modification via a proof-of-concept haptic feedback-sensorized shoe

2020 ◽  
Vol 107 ◽  
pp. 109789
Author(s):  
Haisheng Xia ◽  
Jesse M. Charlton ◽  
Peter B. Shull ◽  
Michael A. Hunt
Keyword(s):  
Haptic Feedback ◽  
Proof Of Concept ◽  
Foot Progression Angle ◽  
Gait Modification

scholarly journals Touching the Void: Exploring Virtual Objects through a Vibrotactile Glove

2012 ◽  
Vol 11 (3) ◽  
pp. 19-24 ◽  
Author(s):  
Elias Giannopoulos ◽  
Ausias Pomes ◽  
Mel Slater
Keyword(s):  
Virtual Environment ◽  
Haptic Feedback ◽  
Low Cost ◽  
Proof Of Concept ◽  
Haptic Interaction ◽  
Development Environment ◽  
Virtual Objects ◽  
Kinect Camera ◽  
Potential Applications ◽  
Different Shapes

This paper describes a simple low-cost approach to adding an element of haptic interaction within a virtual environment. Using off-the-shelf hardware and software we describe a simple setup that can be used to explore physically virtual objects in space. This setup comprises of a prototype glove with a number of vibrating actuators to provide the haptic feedback, a Kinect camera for the tracking of the user's hand and a virtual reality development environment. As proof of concept and to test the efficiency of the system as well as its potential applications, we developed a simple application where we created 4 different shapes within a virtual environment in order to try to explore them and guess their shape through touch alone.

scholarly journals Mixed-Reality and Traditional Flight Simulators for Urban Air Mobility Vehicles

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Keegan Bergman
Keyword(s):  
Haptic Feedback ◽  
Mixed Reality ◽  
Control Panel ◽  
Urban Air ◽  
Vehicle Concept ◽  
Proof Of Concept ◽  
Virtual Control ◽  
Flight Simulators ◽  
Dramatic Rise ◽  
Langley Research Center

The 2018 NASA Academy at Langley Research Center created proof-of-concept mixed reality (MR) and traditional simulators to enable quick vehicle concept prototyping and data collection for human factors studies. Urban Air Mobility (UAM) vehicle concepts were implemented as the focus for these simulators due to recent and dramatic rise in subject interest. The team used X-Plane 11 to model flight dynamics, and Unity for the virtual reality (VR) aspect of the MR simulator and to model the control panel in the traditional simulator. A physical version of the virtual control panel was also fabricated to provide haptic feedback to maintain the immersion for the MR simulator.

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