A high-density electrode array for a cochlear prosthesis

Author(s):  
P.T. Bhatti ◽  
B.Y. Arcand ◽  
J. Wang ◽  
N.V. Butala ◽  
C.R. Friedrich ◽  
...  
2020 ◽  
Vol 5 (8) ◽  
pp. 2000325 ◽  
Author(s):  
Brendan B. Murphy ◽  
Patrick J. Mulcahey ◽  
Nicolette Driscoll ◽  
Andrew G. Richardson ◽  
Gregory T. Robbins ◽  
...  

2010 ◽  
Vol 19 ◽  
pp. S87-S88
Author(s):  
D. Lau ◽  
L. Mackenzie ◽  
N. Shipp ◽  
P. Kuklik ◽  
H. Dimitri ◽  
...  

2004 ◽  
Vol 96 (1) ◽  
pp. 327-336 ◽  
Author(s):  
B. G. Lapatki ◽  
J. P. van Dijk ◽  
I. E. Jonas ◽  
M. J. Zwarts ◽  
D. F. Stegeman

Although the value of high-density surface electromyography (sEMG) has already been proven in fundamental research and for specific diagnostic questions, there is as yet no broad clinical application. This is partly due to limitations of construction principles and application techniques of conventional electrode array systems. We developed a thin, highly flexible, two-dimensional multielectrode sEMG grid, which is manufactured by using flexprint techniques. The material used as electrode carrier (Polyimid, 50 μm thick) allows grids to be cut out in any required shape or size. One universal grid version can therefore be used for many applications, thereby reducing costs. The reusable electrode grid is attached to the skin by using specially prepared double-sided adhesive tape, which allows the selective application of conductive cream only directly below the detection surfaces. To explore the practical possibilities, this technique was applied in single motor unit analysis of the facial musculature. The high mechanical flexibility allowed the electrode grid to follow the skin surface even in areas with very uneven contours, resulting in good electrical connections in the whole recording area. The silverchloride surfaces of the electrodes and their low electrode-to-skin impedances guaranteed high baseline stability and a low signal noise level. The electrode-to-skin attachment proved to withstand saliva and great tensile forces due to mimic contractions. The inexpensive, universally adaptable and minimally obstructive sensor allows the principal advantages of high-density sEMG to be extended to all skeletal muscles accessible from the skin surface and may lay the foundation for more broad clinical application of this noninvasive, two-dimensional sEMG technique.


2019 ◽  
Author(s):  
Chia-Han Chiang ◽  
Jaejin Lee ◽  
Charles Wang ◽  
Ashley J. Williams ◽  
Timothy H. Lucas ◽  
...  

AbstractOBJECTIVEA fundamental goal of the auditory system is to parse the auditory environment into distinct perceptual representations. Auditory perception is mediated by the ventral auditory pathway, which includes the ventrolateral prefrontal cortex (vlPFC) late. Because large-scale recordings of auditory signals are quite rare, the spatiotemporal resolution of the neuronal code that underlies vlPFC’s contribution to auditory perception has not been fully elucidated. Therefore, we developed a modular, chronic, high-resolution, multi-electrode array system with long-term viability.APPROACHWe molded three separate μECoG arrays into one and implanted this system in a non-human primate. A custom 3D-printed titanium chamber was mounted on left hemisphere. The molded 294-contact μECoG array was implanted subdurally over vlPFC. μECoG activity was recorded while the monkey participated in a “hearing-in-noise” task in which they reported hearing a “target” vocalization from a background “chorus” of vocalizations. We titrated task difficulty by varying the sound level of the target vocalization, relative to the chorus (target-to-chorus ratio, TCr).MAIN RESULTSWe decoded the TCr and the monkey’s behavioral choices from the μECoG signal. We analyzed decoding capacity as a function of neuronal frequency band, spatial resolution, and time from implantation. Over a one-year period, we were successfully able to record μECoG signals. Although we found significant decoding with as few as two electrodes, we found near-perfect decoding with ∼16 electrodes. Decoding further improved when we included more electrodes. Finally, because the decoding capacity of individual electrodes varied on a day-by-day basis, high-density electrode arrays ensure robust decoding in the long term.SIGNIFICANCEOur results demonstrate the utility and robustness of high-resolution chronic µECoG recording. We developed a new high-resolution surface electrode array that can be scaled to cover larger cortical areas without increasing the chamber footprint.


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