scholarly journals Topic Detection based on Deep Learning Language Model in Turkish Microblogs

Author(s):  
Furkan Sahinuc ◽  
Cagri Toraman ◽  
Aykut Koc
2021 ◽  
Author(s):  
Andrew E Blanchard ◽  
John Gounley ◽  
Debsindhu Bhowmik ◽  
Mayanka Chandra Shekar ◽  
Isaac Lyngaas ◽  
...  

The COVID-19 pandemic highlights the need for computational tools to automate and accelerate drug design for novel protein targets. We leverage deep learning language models to generate and score drug candidates based on predicted protein binding affinity. We pre-trained a deep learning language model (BERT) on ~9.6 billion molecules and achieved peak performance of 603 petaflops in mixed precision. Our work reduces pre-training time from days to hours, compared to previous efforts with this architecture, while also increasing the dataset size by nearly an order of magnitude. For scoring, we fine-tuned the language model using an assembled set of thousands of protein targets with binding affinity data and searched for inhibitors of specific protein targets, SARS-CoV-2 Mpro and PLpro. We utilized a genetic algorithm approach for finding optimal candidates using the generation and scoring capabilities of the language model. Our generalizable models accelerate the identification of inhibitors for emerging therapeutic targets.


JAMIA Open ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Andrew Wen ◽  
Mohamed Y Elwazir ◽  
Sungrim Moon ◽  
Jungwei Fan

Abstract Objectives To adapt and evaluate a deep learning language model for answering why-questions based on patient-specific clinical text. Materials and Methods Bidirectional encoder representations from transformers (BERT) models were trained with varying data sources to perform SQuAD 2.0 style why-question answering (why-QA) on clinical notes. The evaluation focused on: (1) comparing the merits from different training data and (2) error analysis. Results The best model achieved an accuracy of 0.707 (or 0.760 by partial match). Training toward customization for the clinical language helped increase 6% in accuracy. Discussion The error analysis suggested that the model did not really perform deep reasoning and that clinical why-QA might warrant more sophisticated solutions. Conclusion The BERT model achieved moderate accuracy in clinical why-QA and should benefit from the rapidly evolving technology. Despite the identified limitations, it could serve as a competent proxy for question-driven clinical information extraction.


AI ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 1-16
Author(s):  
Juan Cruz-Benito ◽  
Sanjay Vishwakarma ◽  
Francisco Martin-Fernandez ◽  
Ismael Faro

In recent years, the use of deep learning in language models has gained much attention. Some research projects claim that they can generate text that can be interpreted as human writing, enabling new possibilities in many application areas. Among the different areas related to language processing, one of the most notable in applying this type of modeling is programming languages. For years, the machine learning community has been researching this software engineering area, pursuing goals like applying different approaches to auto-complete, generate, fix, or evaluate code programmed by humans. Considering the increasing popularity of the deep learning-enabled language models approach, we found a lack of empirical papers that compare different deep learning architectures to create and use language models based on programming code. This paper compares different neural network architectures like Average Stochastic Gradient Descent (ASGD) Weight-Dropped LSTMs (AWD-LSTMs), AWD-Quasi-Recurrent Neural Networks (QRNNs), and Transformer while using transfer learning and different forms of tokenization to see how they behave in building language models using a Python dataset for code generation and filling mask tasks. Considering the results, we discuss each approach’s different strengths and weaknesses and what gaps we found to evaluate the language models or to apply them in a real programming context.


2020 ◽  
Vol 14 (4) ◽  
pp. 471-484
Author(s):  
Suraj Shetiya ◽  
Saravanan Thirumuruganathan ◽  
Nick Koudas ◽  
Gautam Das

Accurate selectivity estimation for string predicates is a long-standing research challenge in databases. Supporting pattern matching on strings (such as prefix, substring, and suffix) makes this problem much more challenging, thereby necessitating a dedicated study. Traditional approaches often build pruned summary data structures such as tries followed by selectivity estimation using statistical correlations. However, this produces insufficiently accurate cardinality estimates resulting in the selection of sub-optimal plans by the query optimizer. Recently proposed deep learning based approaches leverage techniques from natural language processing such as embeddings to encode the strings and use it to train a model. While this is an improvement over traditional approaches, there is a large scope for improvement. We propose Astrid, a framework for string selectivity estimation that synthesizes ideas from traditional and deep learning based approaches. We make two complementary contributions. First, we propose an embedding algorithm that is query-type (prefix, substring, and suffix) and selectivity aware. Consider three strings 'ab', 'abc' and 'abd' whose prefix frequencies are 1000, 800 and 100 respectively. Our approach would ensure that the embedding for 'ab' is closer to 'abc' than 'abd'. Second, we describe how neural language models could be used for selectivity estimation. While they work well for prefix queries, their performance for substring queries is sub-optimal. We modify the objective function of the neural language model so that it could be used for estimating selectivities of pattern matching queries. We also propose a novel and efficient algorithm for optimizing the new objective function. We conduct extensive experiments over benchmark datasets and show that our proposed approaches achieve state-of-the-art results.


Author(s):  
Xinhuan Chen ◽  
Yong Zhang ◽  
Chunxiao Xing ◽  
Xiao Liu ◽  
Hsinchun Chen

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