Selection of optimal parameters for automatic analysis of speech disorders in Parkinson's disease

2011 ◽  
Author(s):  
Jiri Mekyska ◽  
Irena Rektorova ◽  
Zdenek Smekal
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Speech Disorders ◽  
Automatic Analysis ◽  
Optimal Parameters ◽  
Selection Of

scholarly journals Acoustic voice assessment in Parkinson's disease patients submitted to posteroventral pallidotomy

2005 ◽  
Vol 63 (1) ◽  
pp. 20-25 ◽  
Author(s):  
Lucia Figueiredo Mourão ◽  
Patrícia Maria de Carvalho Aguiar ◽  
Fernando Antônio Patriani Ferraz ◽  
Mara Suzana Behlau ◽  
Henrique Ballalai Ferraz
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Postoperative Complications ◽  
Speech Disorders ◽  
Acoustic Parameters ◽  
Voice Assessment ◽  
Before And After ◽  
Posteroventral Pallidotomy

Long-term complications in levodopa treated Parkinson's disease (PD) patients caused a resurgence of interest in pallidotomy as an option of treatment. However, postoperative complications such as speech disorders can occur. PURPOSE: The aim of this study is to evaluate the acoustic voice in PD patients, before and after posteroventral pallidotomy. METHOD: Twelve patients with PD were submitted to neurological and voice assessments during the off and on phases, in the pre-operative, 1st and 3rd post-operative months. The patients were evaluated with the UPDRS and the vocal acoustic parameters - f0, NHR, jitter, PPQ, Shimmer, APQ (using the software MultiSpeech - Kay Elemetrics - 3700). RESULTS: The off phase UPDRS scores revealed a tendency to improvement at the 1st month and the off phase worsened. The shimmer and APQ improved. CONCLUSION: This study shows that pallidotomy has little improvement on functional use of communication of PD patients.

scholarly journals Impact of levodopa treatment in the voice pattern of Parkinson’s disease patients: a systematic review and meta-analysis

CoDAS ◽  
2018 ◽  
Vol 30 (5) ◽  
Author(s):  
Patrícia Pinho ◽  
Larissa Monteiro ◽  
Maria Francisca de Paula Soares ◽  
Lorena Tourinho ◽  
Ailton Melo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Acoustic Analysis ◽  
Meta Analysis ◽  
Speech Disorders ◽  
Levodopa Therapy ◽  
Eligibility Criteria ◽  
Perceptual Analysis ◽  
Vocal Intensity

Abstract Purpose Investigate the association between levodopa therapy and vocal characteristics in Parkinson’s disease patients. Search strategy Studies published at MEDLINE, LILACS, and SciELO, from 1960 to December 2016. A systematic review and meta-analysis was performed using the following keywords: Parkinson’s disease; levodopa; L-dopa; voice; speech disorders; dysphonia; dysarthria. After analyzing titles and abstracts, two independent reviewers selected all clinical trials that met the eligibility criteria and selected the articles and the data recorded in a previously standardized table. Selection criteria Trials published in English between 1960 and December 2016 individuals with clinical diagnosis of Parkinson’s disease; use of levodopa therapy in stable doses; acoustic analysis combined or not with auditory-perceptual analysis to evaluate the vocal parameters under investigation. Data analysis The following vocal parameters were analyzed: fundamental frequency (F 0), jitter, and vocal intensity. Standardized mean differences (SMD) were calculated using the Comprehensive Meta-analysis V2 software. Results Nine articles met the eligibility criteria and were selected, with a total of 119 individuals. From these, six articles with 83 individuals were included in the meta-analysis. During the levodopa therapy “on” state, modifications in F 0 (SMD=0.39; 95% CI - 0.21-0.57) and jitter (SMD=0.23; 95% CI - 0.02-0.45) were observed. Vocal intensity was not affected (SMD=0.09; 95% CI - 0.22-0.39) by levodopa ingestion. Data of the included studies were controversial in the auditory-perceptual analysis of voice. Conclusion Levodopa therapy modifies F0 and jitter. No changes in vocal intensity were observed in either the “on” or “off” states of levodopa therapy.

scholarly journals Dementia with Parkinson's disease: Clinical diagnosis, neuropsychological aspects and treatment

2008 ◽  
Vol 2 (4) ◽  
pp. 261-266
Author(s):  
Jorge Lorenzo Otero
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Lewy Body ◽  
Task Force ◽  
Lewy Body Dementia ◽  
Data Bases ◽  
Main Text ◽  
Clinical Diagnoses ◽  
Movement Disorder Society ◽  
Selection Of

Abstract Dementia with Parkinson's disease represents a controversial issue in the complex group of alpha-synucleinopathies. The author acknowledges the concept of a "continuum" between Parkinson disease's (PD), Lewy body dementia (LBD), and dementia in Parkinson's disease (PDD). However, the practicing neurologist needs to identify the phenotypic signs of each dementia. The treatment and prognosis are different in spite of the overlaps between them. The main aim of this review was to characterize the clinical diagnoses of dementia associated with Parkinson's disease (PDD). Secondarily, the review discussed some epidemiological and neuropsychological issues. Selection of articles was not systematic and reflects the author's opinion, where the main text selected was the recommendations from the Movement Disorder Society Task Force for PDD diagnosis. The Pub Med, OVID, and Proquest data bases were used for the search.

scholarly journals ParkinSong: A Controlled Trial of Singing-Based Therapy for Parkinson’s Disease

2019 ◽  
Vol 33 (6) ◽  
pp. 453-463 ◽  
Author(s):  
Jeanette Tamplin ◽  
Meg E. Morris ◽  
Caterina Marigliani ◽  
Felicity A. Baker ◽  
Adam P. Vogel
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Controlled Trial ◽  
Speech Disorders ◽  
Life Outcomes ◽  
Related Quality ◽  
Vocal Intensity ◽  
Structural Mechanisms

Background. Communication impairment is one of the most common symptoms of Parkinson’s disease (PD), significantly affecting quality of life. Singing shares many of the neural networks and structural mechanisms used during speech and, thus, has potential for therapeutic application to address speech disorders. Objective. To explore the effects of an interdisciplinary singing-based therapeutic intervention (ParkinSong) on voice and communication in people with PD. Methods. A controlled trial compared the effects of the ParkinSong intervention with an active control condition at 2 dosage levels (weekly vs monthly) over 3 months, on voice, speech, respiratory strength, and voice-related quality-of-life outcomes for 75 people living with PD. The interdisciplinary ParkinSong model comprised high-effort vocal and respiratory tasks, speech exercises, group singing, and social communication opportunities. Results. ParkinSong intervention participants demonstrated significant improvements in vocal intensity ( P = .018), maximum expiratory pressure ( P = .032), and voice-related quality of life ( P = .043) in comparison to controls. Weekly ParkinSong participants increased vocal intensity more than monthly participants ( P = .011). Vocal intensity declined in nontreatment control groups. No statistical differences between groups on maximum phonation length or maximum inspiratory pressure were observed at 3 months. Conclusions. ParkinSong is an engaging intervention with the potential to increase loudness and respiratory function in people with mild to moderately severe PD.

scholarly journals Standardised Neuropsychological Assessment for the Selection of Patients Undergoing DBS for Parkinson’s Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Jennifer A. Foley ◽  
Tom Foltynie ◽  
Patricia Limousin ◽  
Lisa Cipolotti
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Mood Disorder ◽  
Neuropsychological Assessment ◽  
Careful Consideration ◽  
Baseline Risk ◽  
General Decline ◽  
Before And After ◽  
Selection Of

DBS is an increasingly offered advanced treatment for Parkinson’s disease (PD). Neuropsychological assessment is considered to be an important part of the screening for selection of candidates for this treatment. However, no standardised screening procedure currently exists. In this study, we examined the use of our standardised neuropsychological assessment for the evaluation of surgical candidates and to identify risk factors for subsequent decline in cognition and mood. A total of 40 patients were assessed before and after DBS. Evaluation of mood and case notes review was also undertaken. Before DBS, patients with PD demonstrated frequent impairments in intellectual functioning, memory, attention, and executive function, as well as high rates of mood disorder. Post-DBS, there was a general decline in verbal fluency only, and in one patient, we documented an immediate and irreversible global cognitive decline, which was associated with older age and more encompassing cognitive deficits at baseline. Case note review revealed that a high proportion of patients developed mood disorder, which was associated with higher levels of depression at baseline and greater reduction in levodopa medication. We conclude that our neuropsychological assessment is suitable for the screening of candidates and can identify baseline risk factors, which requires careful consideration before and after surgery.

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