Relative Blood Volume Estimation from Clinical Super-Resolution US Imaging in Breast Cancer

Author(s):  
Stefanie Dencks ◽  
Marion Piepenbrock ◽  
Tatjana Opacic ◽  
Barbara Krauspe ◽  
Elmar Stickeler ◽  
...  
2021 ◽  
pp. 1-8
Author(s):  
José Rodríguez-Chagolla ◽  
Raúl Cartas-Rosado ◽  
Claudia Lerma ◽  
Oscar Infante-Vázquez ◽  
Raúl Martínez-Memije ◽  
...  

<b><i>Introduction:</i></b> Patients in hemodiafiltration (HDF) eliminate volume overload by ultrafiltration. Vascular volume loss is among the main mechanisms contributing to adverse events such as intradialytic hypotension. Here, we hypothesize that the intradialytic exercise (IDEX) is an intervention that could improve the acute response of physiological mechanisms involved during vascular volume loss. To test this hypothesis, we evaluated the hemodynamic response to mild aerobic exercise during HDF. <b><i>Methods:</i></b> Nineteen end-stage renal disease (ESRD) patients (11 women: 40 ± 10.8 years old, and 8 men: 42 ± 21 years old) receiving HDF thrice a week, with 6 months of previous physical conditioning, participated in this study. Three HDF sessions were scheduled for each patient: 1 resting in supine position, 1 resting in sitting position, and 1 doing aerobic exercise. The first 2 sessions were taken as control. The ultrafiltration rate was set to 800 mL/h in each session. The hemodynamic response was monitored through the relative blood volume (RBV), and cardiovascular variables measured noninvasively by photoplethysmography. Adequacy variables such as Kt/V and percentage reduction of urate, urea, creatinine (Cr), and phosphate were also monitored. <b><i>Findings:</i></b> The decrease rate of the RBV was smaller in the session with IDEX compared to the sessions with no exercise. No differences were found neither in the cardiovascular variables nor in the adequacy variables among the 3 sessions. There were no hypotension events during the session with exercise, and 8 events during the sessions without exercise (<i>p</i> = 0.002). <b><i>Discussion:</i></b> Mild exercise during HDF decreased the RBV drop and was associated with less hypotension events. The lack of differences in the hemodynamic variables suggests an adequate acute response of cardiovascular compensation variables to intradialytic hypovolemia.


1990 ◽  
Vol 5 (3-4) ◽  
pp. 138-146 ◽  
Author(s):  
Line Leduc ◽  
Kenneth J. Moise, Jr. ◽  
Robert J. Carpenter, Jr. ◽  
Lorraine E. Cano

1987 ◽  
Vol 22 (2) ◽  
pp. 219-219
Author(s):  
O Linderkamp ◽  
K Lorenzen ◽  
C Schmid ◽  
H T Versmold ◽  
K P Riegel

2014 ◽  
Vol 27 (9) ◽  
pp. 1085-1093 ◽  
Author(s):  
Andreas Pohlmann ◽  
Peter Karczewski ◽  
Min-Chi Ku ◽  
Babette Dieringer ◽  
Helmar Waiczies ◽  
...  

ASAIO Journal ◽  
2007 ◽  
Vol 53 (3) ◽  
pp. 357-364 ◽  
Author(s):  
Judith J. Dasselaar ◽  
Roel M. Huisman ◽  
Paul E. de Jong ◽  
Johannes G. M. Burgerhof ◽  
Casper F. M. Franssen

Author(s):  
Stefanie Dencks ◽  
Marion Piepenbrock ◽  
Tatjana Opacic ◽  
Barbara Krauspe ◽  
Elmar Stickeler ◽  
...  

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii247-iii248
Author(s):  
Susanne Kron ◽  
Reinhard Wenkel ◽  
Til Leimbach ◽  
Sabine Aign ◽  
Joachim Kron

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Marta Álvarez Nadal ◽  
Elizabeth Viera Ramírez ◽  
Irene Martin ◽  
Gloria Ruíz-Roso López ◽  
María Delgado Yagüe ◽  
...  

Abstract Background and Aims The imbalance between UF and refilling rate is considered a major cause for intradialytic hypotension. Recent studies report a feasable and noninvasive method to estimate vascular refilling by determining absolute blood volume. It was the aim of this study to analyze absolute blood volume in a group of haemodialysis patients and to examine vascular refilling volume. Method Thirty stable chronic HD patients were studied (36,7% female, 63,3% male), aged 71,07 ± 13,31 years. Dialysis duration and UF requirements were based on physician prescription. Vascular refilling was calculated as: VREF = VUF – ΔV, where ΔV is the difference between absolute blood volume at the beginning and the end of dialysis. Relative blood volume monitor (BVM) was used. Hemodial Int. 2016;20(3):484–91. Results Absolute blood volume at the beginning of the dialysis was 6,27 ± 2,78 L (92,44 ± 32,66 ml/kg) and at the end 5,83 ± 2,77 L (85,94 ± 30,44 ml/kg). Ultrafiltration (UF) volume was 2,64 ± 0,82 L (11,14 ± 4,02 ml/kg/h). Vascular refilling was calculated as 2,24 ± 0,74 L, with a refilling fraction of 85,33 ± 11,07%. We found a strong correlation between refilling volume and UF volume (r2 0,861) (Figure 1), and a mild correlation between refilling volume and predialysis volume overload (r2 0,529). Conclusion Measurement of absolute blood volume is easy and noninvasive, and it allows us to study refilling volume. We found a strong correlation between UF volume and refilling volume.


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