Thermal imaging is a non-destructive, non-contact and rapid system. It reports temperature through measuring infrared radiation emanated by an object/ material surface. Automated thermal imaging system involves thermal camera equipped with infrared detectors, signal processing unit and image acquisition system supported by computer. It is elaborated in wide domains applications. Extensive focus is directed to the thermal imaging in the medical domain especially breast cancer detection. This chapter provided the main concept and the different applications of thermal imaging. It explores and analyses several works in the light of studding the thermograph. It is an effective screening tool for breast cancer prediction. Studies justify that thermography can be considered a complementary tool to detect breast diseases. The current chapter reviews many usages and limitations of thermography in biomedical field. Extensive recommendations for future directions are summarized to provide a structured vision of breast thermography.