The potential use of the
            Penicillium chrysogenum
            antifungal protein PAF, the designed variant PAF
            opt
            and its γ‐core peptide Pγ
            opt
            in plant protection

The fungus Clonostachys rosea was recognized as an aggressive parasite on other fungi already in the late 1950s. Research into its potential use in biological control of plant diseases soon followed. Today, there are several commercial products based on C. rosea available for biocontrol applications worldwide. Although its mycoparasitic ability has attracted a lot of interest, C. rosea is now viewed as an ecological generalist whose lifestyle also includes plant endophytism, rhizosphere competence and polyphagous ability. Protocols for producing high amounts of C. rosea spores are available for both solid state and liquid fermentation. Low temperature and low moisture content are key factors that influence the shelf life of C. rosea propagules. Products based on C. rosea can be delivered to flowers using bumble bees, applied by spraying or as seed dressing or by incorporation into the soil. Clonostachys rosea is today an established factor in sustainable plant protection strategies.

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Carbene-catalyzed enal γ-carbon addition to α-ketophosphonates for enantioselective access to bioactive 2-pyranylphosphonates

Chemical Communications ◽

10.1039/c8cc03017k ◽

2018 ◽

Vol 54 (47) ◽

pp. 6040-6043 ◽

Cited By ~ 8

Author(s):

Jun Sun ◽

Fangcheng He ◽

Zhongyao Wang ◽

Dingwu Pan ◽

Pengcheng Zheng ◽

...

Keyword(s):

Plant Protection ◽

Carbon Addition ◽

Potential Use

A carbene-catalyzed [4+2] reaction of enals and α-ketophosphonates is developed to afford chiral 2-pyranylphosphonates with potential use in plant protection.

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The small molecular mass antifungal protein of Penicillium chrysogenum - a mechanism of action oriented review

Journal of Basic Microbiology ◽

10.1002/jobm.201100041 ◽

2011 ◽

Vol 51 (6) ◽

pp. 561-571 ◽

Cited By ~ 26

Author(s):

Nikoletta Hegedűs ◽

Éva Leiter ◽

Barbara Kovács ◽

Valéria Tomori ◽

Nak-Jung Kwon ◽

...

Keyword(s):

Molecular Mass ◽

Mechanism Of Action ◽

Penicillium Chrysogenum ◽

Antifungal Protein

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The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF

Frontiers in Microbiology ◽

10.3389/fmicb.2018.01655 ◽

2018 ◽

Vol 9 ◽

Cited By ~ 8

Author(s):

Christoph Sonderegger ◽

Györgyi Váradi ◽

László Galgóczy ◽

Sándor Kocsubé ◽

Wilfried Posch ◽

...

Keyword(s):

Penicillium Chrysogenum ◽

Antifungal Protein ◽

Core Motif

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Characterization of the novel antifungal protein PgAFP and the encoding gene of Penicillium chrysogenum

Peptides ◽

10.1016/j.peptides.2009.11.002 ◽

2010 ◽

Vol 31 (4) ◽

pp. 541-547 ◽

Cited By ~ 39

Author(s):

Andrea Rodríguez-Martín ◽

Raquel Acosta ◽

Susan Liddell ◽

Félix Núñez ◽

Mª José Benito ◽

...

Keyword(s):

Penicillium Chrysogenum ◽

Antifungal Protein ◽

The Novel ◽

Encoding Gene

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Purification and characterization of a novel antifungal protein secreted by Penicillium chrysogenum from an Arctic sediment

Applied Microbiology and Biotechnology ◽

10.1007/s00253-013-4800-6 ◽

2013 ◽

Vol 97 (24) ◽

pp. 10381-10390 ◽

Cited By ~ 19

Author(s):

Zhiteng Chen ◽

Jingqun Ao ◽

Wenchuan Yang ◽

Liping Jiao ◽

Tianling Zheng ◽

...

Keyword(s):

Penicillium Chrysogenum ◽

Antifungal Protein ◽

Purification And Characterization ◽

Arctic Sediment

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Characterization of the Penicillium chrysogenum antifungal protein PAF

Archives of Microbiology ◽

10.1007/s00203-003-0578-8 ◽

2003 ◽

Vol 180 (3) ◽

pp. 204-210 ◽

Cited By ~ 88

Author(s):

Lydia Kaiserer ◽

Christoph Oberparleiter ◽

Renate Weiler-G�rz ◽

Wolfgang Burgstaller ◽

Eva Leiter ◽

...

Keyword(s):

Penicillium Chrysogenum ◽

Antifungal Protein

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In vitro activity of Penicillium chrysogenum antifungal protein (PAF) and its combination with fluconazole against different dermatophytes

Antonie van Leeuwenhoek ◽

10.1007/s10482-008-9263-x ◽

2008 ◽

Vol 94 (3) ◽

pp. 463-470 ◽

Cited By ~ 19

Author(s):

László Galgóczy ◽

Tamás Papp ◽

István Pócsi ◽

Nikoletta Hegedűs ◽

Csaba Vágvölgyi

Keyword(s):

Penicillium Chrysogenum ◽

Vitro Activity ◽

Antifungal Protein ◽

In Vitro Activity

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Biodegradable Blends of Grafted Dextrin with PLGA-block-PEG Copolymer as a Carrier for Controlled Release of Herbicides into Soil

Materials ◽

10.3390/ma13040832 ◽

2020 ◽

Vol 13 (4) ◽

pp. 832 ◽

Cited By ~ 1

Author(s):

Kamila Lewicka ◽

Piotr Rychter ◽

Małgorzata Pastusiak ◽

Henryk Janeczek ◽

Piotr Dobrzynski

Keyword(s):

Controlled Release ◽

Polymer Matrix ◽

Enzymatic Degradation ◽

Plant Protection ◽

Degradation Products ◽

The Matrix ◽

Poly Ethylene Oxide ◽

Poly Ethylene ◽

Unchanged Form ◽

Potential Use

The presented work aimed to test influence of poly(L-lactide-co-glycolide)-block-poly (ethylene oxide) copolymer modification by blending with grafted dextrin or maltodextrin on the course of degradation in soil and the usefulness of such material as a matrix in the controlled release of herbicides. The modification should be to obtain homogenous blends with better susceptibility to enzymatic degradation. Among all tested blends, which were proposed as a carrier for potential use in the controlled release of plant protection agents, PLGA-block-PEG copolymer blended with grafted dextrin yielded very promising results for their future applications, and what is very importantly proposed formulations provide herbicides in unchanged form into soil within few months of release. The modification PLAGA/PEG copolymer by blending with modificated dextrins affects the improvement of the release profile. The weekly release rates for both selected herbicides (metazachlor and pendimethalin) were constant for a period of 12 weeks. Enzymatic degradation of modified dextrin combined with leaching of the degradation products into medium caused significant erosion of the polymer matrix, thereby leading to acceleration of water diffusion into the polymer matrix and allowing for easier leaching of herbicides outside the matrix.

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