scholarly journals Survival rates after lobectomy versus sublobar resection for early-stage right middle lobe non-small cell lung cancer

2018 ◽  
Vol 9 (8) ◽  
pp. 1026-1031 ◽  
Author(s):  
Xiayi Lv ◽  
Jinlin Cao ◽  
Xiaona Dai ◽  
Aizemaiti Rusidanmu
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Early Stage ◽  
Survival Rates ◽  
Middle Lobe ◽  
Small Cell ◽  
Sublobar Resection ◽  
Small Cell Lung ◽  
Right Middle Lobe

Concurrent Hyperfractionated Radiotherapy and Low-Dose Daily Carboplatin/Paclitaxel in Patients With Early-Stage (I/II) Non–Small-Cell Lung Cancer: Long-Term Results of a Phase II Study

2005 ◽  
Vol 23 (28) ◽  
pp. 6873-6880 ◽  
Author(s):  
Branislav Jeremić ◽  
Biljana Milicić ◽  
Ljubisa Acimović ◽  
Slobodan Milisavljević
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Low Dose ◽  
Early Stage ◽  
Survival Rates ◽  
Small Cell ◽  
Stage I ◽  
Small Cell Lung ◽  
Local Progression

PurposeFeasibility and activity of concurrent hyperfractionated radiotherapy (Hfx RT) and low-dose, daily carboplatin and paclitaxel were investigated in patients with early-stage (I/II) non–small-cell lung cancer in a phase II study.Patients and MethodsFifty-six patients started their treatment on day 1 with 30 mg/m2of paclitaxel. Hfx RT using 1.3 Gy bid to a total dose of 67.6 Gy and concurrent low-dose daily carboplatin 25 mg/m2and paclitaxel 10 mg/m2, both given Mondays through Fridays during the RT course, started from the second day.ResultsThere were 29 complete responses (52%) and 15 partial responses (27%), and 12 patients (21%), experienced stable disease. The median survival time was 35 months, and 3- and 5-year survival rates were 50% and 36%, respectively. The median time to local progression has not been achieved, but 3- and 5-year local progression-free survival rates were 56% and 54%, respectively. The median time to distant metastasis has not been achieved, but 3- and 5- year distant metastasis-free survival rates were 61% and 61%, respectively. The median and 5-year cause-specific survivals were 39 months and 43%, respectively. Acute high-grade (> 3) toxicity was hematologic (22%), esophageal (7%), or bronchopulmonary (7%). No grade 5 toxicity was observed. Late high-grade toxicity was rarely observed (total, 10%).ConclusionHfx RT and concurrent low-dose daily carboplatin/paclitaxel was feasible with low toxicity and effective in patients with stage I/II non–small-cell lung cancer. It should continue to be investigated for this disease.

Intraoperative 125I Brachytherapy Mesh After Sublobar Resection in Early Stage High Risk Non Small Cell Lung Cancer

Brachytherapy ◽  
2011 ◽  
Vol 10 ◽  
pp. S23-S24 ◽  
Author(s):  
Mohsen Isaac ◽  
Anna Kaminsky ◽  
Victor G. Onufrey ◽  
Jason Lamb ◽  
Judith Figura
Keyword(s):  
Lung Cancer ◽  
High Risk ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Early Stage ◽  
Small Cell ◽  
Sublobar Resection ◽  
Small Cell Lung ◽  
125I Brachytherapy
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