Undifferentiated pleomorphic sarcoma constitutes less than 5 % of all sarcomas in adults and has been
rarely seen in the breast and is dened as a group of pleomorphic, high-grade sarcomas in which any
attempt to disclose their line of differentiation has failed . Most undifferentiated pleomorphic sarcomas(UPS) have occurred in
their sixth and seventh decades of life and very rarely in adolescents and adults.
We report a case of 24 year old female presented with painless lump in right breast and rapidly increasing in size for last 5
months. Iinitial diagnosis was made as sarcoma breast on the basis of physical and radiological examination. After that total
mastectomy was done without axillary lymph node dissection, as lymphatic spread is very rare. But without histopathological
examination and most importantly IHC-panel, it is impossible to make a denitive diagnosis of UPS breast.
Mediastinal undifferentiated pleomorphic sarcoma with pleural effusion cytopathologically misdiagnosed as epithelial malignant pleural mesothelioma: An autopsy case report
