PRIMARY UNDIFFERENTIATED PLEOMORPHIC SARCOMA OF BREAST IN A 24 YEAR FEMALE : A CASE REPORT

2021 ◽  
pp. 57-58
Author(s):  
Sona Pathak ◽  
Manoj Kumar Paswan ◽  
Arpana ShailalyTirkey ◽  
Joyeeta Mandal
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Histopathological Examination ◽  
Axillary Lymph ◽  
High Grade ◽  
Node Dissection ◽  
Total Mastectomy ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma ◽  
Adolescents And Adults

Undifferentiated pleomorphic sarcoma constitutes less than 5 % of all sarcomas in adults and has been rarely seen in the breast and is dened as a group of pleomorphic, high-grade sarcomas in which any attempt to disclose their line of differentiation has failed . Most undifferentiated pleomorphic sarcomas(UPS) have occurred in their sixth and seventh decades of life and very rarely in adolescents and adults. We report a case of 24 year old female presented with painless lump in right breast and rapidly increasing in size for last 5 months. Iinitial diagnosis was made as sarcoma breast on the basis of physical and radiological examination. After that total mastectomy was done without axillary lymph node dissection, as lymphatic spread is very rare. But without histopathological examination and most importantly IHC-panel, it is impossible to make a denitive diagnosis of UPS breast.

scholarly journals Radiation Field Design in the ACOSOG Z0011 (Alliance) Trial

2014 ◽  
Vol 32 (32) ◽  
pp. 3600-3606 ◽  
Author(s):  
Reshma Jagsi ◽  
Manjeet Chadha ◽  
Janaki Moni ◽  
Karla Ballman ◽  
Fran Laurie ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Lymph Node ◽  
Sentinel Lymph Nodes ◽  
Axillary Lymph ◽  
Nodal Involvement ◽  
Node Dissection ◽  
Acosog Z0011 ◽  
Significant Difference ◽  
Low Volume

Purpose ACOSOG Z0011 established that axillary lymph node dissection (ALND) is unnecessary in patients with breast cancer with one to two positive sentinel lymph nodes (SLNs) who undergo lumpectomy, radiotherapy (RT), and systemic therapy. We sought to ascertain RT coverage of the regional nodes in that trial. Methods We evaluated case report forms completed 18 months after enrollment. From 2012 to 2013, we collected all available detailed RT records for central review. Results Among 605 patients with completed case report forms, 89% received whole-breast RT. Of these, 89 (15%) were recorded as also receiving treatment to the supraclavicular region. Detailed RT records were obtained for 228 patients, of whom 185 (81.1%) received tangent-only treatment. Among 142 with sufficient records to evaluate tangent height, high tangents (cranial tangent border ≤ 2 cm from humeral head) were used in 50% of patients (33 of 66) randomly assigned to ALND and 52.6% (40 of 76) randomly assigned to SLND. Of the 228 patients with records reviewed, 43 (18.9%) received directed regional nodal RT using ≥ three fields: 22 in the ALND arm and 21 in the SLND arm. Those receiving directed nodal RT had greater nodal involvement (P < .001) than those who did not. Overall, there was no significant difference between treatment arms in the use of protocol-prohibited nodal fields. Conclusion Most patients treated in Z0011 received tangential RT alone, and some received no RT at all. Some patients received directed nodal irradiation via a third field. Further research is necessary to determine the optimal RT approach in patients with low-volume axillary disease treated with SLND alone.

scholarly journals Primary malignant melanoma of the nipple: a case report

2021 ◽  
Vol 10 (12) ◽  
pp. 4553
Author(s):  
Moukit Mounir ◽  
Aziz Bazine ◽  
Mohammed Rahmoune ◽  
Ismail Allilou ◽  
Bouchra Elmoubakkir ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Malignant Melanoma ◽  
Axillary Lymph Node ◽  
Primary Melanoma ◽  
Axillary Lymph ◽  
Node Dissection ◽  
Superficial Spreading ◽  
Non Invasive ◽  
Left Nipple

Primary melanoma origi­nating on the female nipple remains an extremely rare variant of malignant melanoma and only a few cases haves been reported in the literature. We describe a case of a patient admitted for a black pigment deposition on the left nipple. Surgical resection of the left nipple and areola with clear margins and an axillary lymph node dissection was performed confirming the diagnosis of non-invasive superficial spreading melanoma.

scholarly journals Thymoma with Coexisting Undifferentiated Pleomorphic Sarcoma: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-5
Author(s):  
Manoranjan Varshney ◽  
Mohammad Shahid ◽  
Veena Maheshwari ◽  
Aysha Mubeen ◽  
Mohammed Azfar Siddiqui
Keyword(s):  
Case Report ◽  
Mediastinal Mass ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Fine Needle ◽  
Pleomorphic Sarcoma ◽  
Needle Aspiration Cytology ◽  
Axillary Lump

We report here a case of thymoma simultaneously associated with undifferentiated pleomorphic sarcoma. A 45-year-old male presented with axillary lump. Radiographic studies showed a mediastinal mass. On fine needle aspiration cytology and histopathological examination, a diagnosis of thymoma with coexisting undifferentiated pleomorphic sarcoma was made. Although thymomas are associated with many extrathymic malignancies, it's association with undifferentiated pleomorphic sarcoma is rare. This case is being reported on to reinforce that clinicians should bear in mind the possibility of extrathymic malignancies in patients with thymomas.

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