Factors associated with non-response at health-related quality of life follow-up in a septic shock trial

2017 ◽  
Vol 62 (3) ◽  
pp. 357-366 ◽  
Author(s):  
M. N. Kjaer ◽  
C. B. Mortensen ◽  
P. B. Hjortrup ◽  
S. L. Rygård ◽  
I. Andersen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Septic Shock ◽  
Shock Trial ◽  
Health Related Quality ◽  
Factors Associated ◽  
Related Quality ◽  
Health Related

scholarly journals 357 Factors associated with changes in health-related quality of life in children with cystic fibrosis during one-year follow-up

2017 ◽  
Vol 16 ◽  
pp. S154
Author(s):  
M. Van Horck ◽  
B. Winkens ◽  
G. Wesseling ◽  
K. de Winter-de Groot ◽  
I. De Vreede ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Health Related Quality ◽  
Factors Associated ◽  
Related Quality ◽  
Health Related ◽  
One Year

scholarly journals Factors associated with changes in health-related quality of life in children with cystic fibrosis during 1-year follow-up

2017 ◽  
Vol 176 (8) ◽  
pp. 1047-1054 ◽  
Author(s):  
Marieke van Horck ◽  
Bjorn Winkens ◽  
Geertjan Wesseling ◽  
Karin de Winter-de Groot ◽  
Ilja de Vreede ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Health Related Quality ◽  
Factors Associated ◽  
Related Quality ◽  
Health Related

scholarly journals Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock

2021 ◽  
Vol 9 ◽  
Author(s):  
Neethi P. Pinto ◽  
Robert A. Berg ◽  
Athena F. Zuppa ◽  
Christopher J. Newth ◽  
Murray M. Pollack ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Septic Shock ◽  
Developmental Delay ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Sepsis Survivors ◽  
Pediatric Sepsis

Background: Although some pediatric sepsis survivors experience worsening health-related quality of life (HRQL), many return to their pre-illness HRQL. Whether children can improve beyond baseline is not known. We examined a cohort of pediatric sepsis survivors to determine if those with baseline HRQL scores below the population mean could exhibit ≥10% improvement and evaluated factors associated with improvement.Methods: In this secondary analysis of the Life After Pediatric Sepsis Evaluation prospective study, children aged 1 month to 18 years admitted to 12 academic PICUs in the United States with community-acquired septic shock who survived to 3 months and had baseline HRQL scores ≤ 80 (i.e., excluding those with good baseline HRQL to allow for potential improvement) were included. HRQL was measured using the Pediatric Quality of Life Inventory or Stein-Jessop Functional Status Scale.Findings: One hundred and seventeen children were eligible. Sixty-one (52%) had ≥ 10% improvement in HRQL by 3 months. Lower pre-sepsis HRQL was associated with increased odds of improvement at 3 months [aOR = 1.08, 95% CI (1.04–1.11), p < 0.001] and 12 months [OR = 1.05, 95% CI (1.02–1.11), p = 0.005]. Improvement in HRQL was most prevalent at 3 month follow-up; at 12 month follow-up, improvement was more sustained among children without severe developmental delay compared to children with severe developmental delay.Interpretation: More than half of these children with community acquired septic shock experienced at least a 10% improvement in HRQL from baseline to 3 months. Children with severe developmental delay did not sustain this improvement at 12 month follow-up.

Factors associated with deterioration of health-related quality of life in multiple system atrophy: 1-year follow-up study

2018 ◽  
Vol 118 (4) ◽  
pp. 589-595 ◽  
Author(s):  
Milica V. Jecmenica-Lukic ◽  
Tatjana D. Pekmezovic ◽  
Igor N. Petrovic ◽  
Natasa T. Dragasevic ◽  
Vladimir S. Kostić
Keyword(s):  
Quality Of Life ◽  
Multiple System Atrophy ◽  
Health Related Quality ◽  
Factors Associated ◽  
Follow Up Study ◽  
Related Quality ◽  
Health Related

Health-related quality of life in survivors of septic shock: 6-month follow-up from the ADRENAL trial

2020 ◽  
Vol 46 (9) ◽  
pp. 1696-1706 ◽  
Author(s):  
Naomi E. Hammond ◽  
◽  
Simon R. Finfer ◽  
Qiang Li ◽  
Colman Taylor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Septic Shock ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Multiple Sclerosis: Change in Health-Related Quality of Life Over Two Years

2009 ◽  
Vol 36 (5) ◽  
pp. 554-561 ◽  
Author(s):  
Wilma M. Hopman ◽  
Helen Coo ◽  
Andrey Pavlov ◽  
Andrew G. Day ◽  
Catherine M. Edgar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Rate Of Change ◽  
Health Related Quality ◽  
Factors Associated ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Background:Cross-sectional research has demonstrated poorer function and health-related quality of life (HRQOL) in those with multiple sclerosis (MS) but less is known about change over time. The goals of this study were to measure change in HRQOL and identify factors associated with change.Methods:HRQOL was assessed at baseline and annually over two subsequent years using the Multiple Sclerosis Quality of Life Inventory. Function was assessed using the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Functional Composite. Annualized rate of change was calculated for all twenty outcomes. Mixed effects modeling (univariate followed by multivariate) was used to examine the associations among patient characteristics and the age- and sex-adjusted Physical Component Summary (PCS) and Mental Component Summary (MCS) at study initiation and over the two years of follow-up.Results:Of 300 participants, 288 (96%) provided at least one assessment and are included in this analysis. Although 14 of the 20 outcomes showed a mean decline, only two (SF-36 physical function, p=0.018 and the EDSS, p<0.001) were statistically significant. The SF-36 social function showed a significant improvement (p=0.031). Only two variables were significantly associated with a decreased rate of decline or improvement over two years, including being female (PCS, p=0.001) and use of visiting nurse services (MCS, p<0.001).Conclusions:HRQOL is relatively stable over two years of follow-up, particularly for mentally-oriented outcomes. Further research with a longer period of follow-up is needed to provide additional insight into factors associated with change in HRQOL in patients with MS.

scholarly journals Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock*

2020 ◽  
Vol 48 (3) ◽  
pp. 319-328 ◽  
Author(s):  
Jerry J. Zimmerman ◽  
Russell Banks ◽  
Robert A. Berg ◽  
Athena Zuppa ◽  
Christopher J. Newth ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Septic Shock ◽  
Critical Illness ◽  
Health Related Quality ◽  
Factors Associated ◽  
Related Quality ◽  
Health Related ◽  
Long Term Mortality
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