scholarly journals Endemic Fungal Infections in Solid Organ Transplantation

2013 ◽  
Vol 13 (s4) ◽  
pp. 250-261 ◽  
Author(s):  
R. Miller ◽  
M. Assi ◽  
Author(s):  
Darius Armstrong James ◽  
Anand Shah ◽  
Anna Reed

Fungal infections are a significant and life-threatening complication of organ transplantation, on a global scale. Risk varies according to transplant type, with liver, lung, and small bowel transplant recipients being at particular risk. Whilst invasive candidiasis is the most common fungal infection in organ transplantation overall, aspergillosis is a particular problem in lung transplantation. In addition, a wide spectrum of fungi may cause invasive disease in organ transplantation, consequently diagnosis and treatment can be challenging. Key challenges are to understand individual risk for infection, appropriate prophylactic strategies, and molecular diagnostic approaches. Treatment options are complicated by drug–drug interactions with transplant therapy, as well as intrinsic allograft dysfunction seen in many patients. In this chapter, we review the epidemiology, risk factors, diagnosis, and management of fungal infections in solid organ transplantation.


2015 ◽  
Vol 99 (9) ◽  
pp. e140-e144 ◽  
Author(s):  
Wolfgang Mutschlechner ◽  
Brigitte Risslegger ◽  
Birgit Willinger ◽  
Martin Hoenigl ◽  
Brigitte Bucher ◽  
...  

2007 ◽  
Vol 45 (4) ◽  
pp. 305-320 ◽  
Author(s):  
Fernanda P. Silveira ◽  
Shahid Husain

2002 ◽  
Vol 2 (7) ◽  
pp. 678-683 ◽  
Author(s):  
Peter S. Miele ◽  
Charles S. Levy ◽  
Margo A. Smith ◽  
Elizabeth M. Dugan ◽  
Richard H. Cooke ◽  
...  

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