scholarly journals The impact of frailty on clinical outcomes in colorectal cancer surgery: A systematic literature review

2021 ◽  
Author(s):  
Mailis Michaud Maturana ◽  
William James English ◽  
Madura Nandakumar ◽  
John Li Chen ◽  
Lee Dvorkin
Keyword(s):  
Colorectal Cancer ◽  
Literature Review ◽  
Clinical Outcomes ◽  
Systematic Literature Review ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
The Impact

The impact of socioeconomic factors on 30-day mortality following elective colorectal cancer surgery: A nationwide study

2009 ◽  
Vol 45 (7) ◽  
pp. 1248-1256 ◽  
Author(s):  
B.L. Frederiksen ◽  
M. Osler ◽  
H. Harling ◽  
Steen Ladelund ◽  
T. Jørgensen
Keyword(s):  
Colorectal Cancer ◽  
Socioeconomic Factors ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Nationwide Study ◽  
The Impact

scholarly journals The impact of chronic kidney disease on post-operative outcomes following elective colorectal cancer surgery

2018 ◽  
Vol 55 ◽  
pp. S44-S45
Author(s):  
J. Wright ◽  
C. Morgan ◽  
Z. Cahilog ◽  
J. Kinross ◽  
A. Von Roon ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Operative Outcomes ◽  
The Impact

Factors affecting chemotherapy use and delay (≥ 8 weeks) after colorectal cancer surgery and the impact of chemotherapy delay on survival.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 784-784
Author(s):  
Ik Yong Kim ◽  
Young Wan Kim
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Cancer Surgery ◽  
Stage Ii ◽  
Stage Iii ◽  
Recurrence Free Survival ◽  
Colorectal Cancer Surgery ◽  
Free Survival ◽  
Factors Affecting ◽  
The Impact

784 Background: To date, reasons for adjuvant chemotherapy (AC) omission and delay have not been extensively studies. This study aimed to evaluate factors affecting chemotherapy use and delay (≥8 weeks) after colorectal cancer surgery and their impact on survival. Methods: Between 2008 and 2013, consecutive 584 patients undergoing major resection for stage II and III colorectal cancer in a single tertiary referral center. Results: Among 584 patients with stage II and III diseases, AC was performed in 460 (78.8%) patients. Regimens included fluorouracil with folinic acid (n=257, 55.9%), FOLFOX (n=134, 29.1%), capecitabline (n=62, 13.5%), and tegafur-uracil (n=7, 1.5%). Factors affecting not receiving AC were older age (>80 years), American Society of Anesthesiologists score (≥3), presence of postoperative complication, and not receiving preoperative chemoradiation. Overall survival was 87.2% (AC +) and 58.5% (no AC, p<0.001) in stage II disease, and 79.5% (AC +) and 24.6% (no AC, p<0.001) in stage III disease, respectively. Recurrence-free survival was 83.7% (AC +) and 61.9% (no AC, p=0.003) in stage II disease, and 60.5%(AC +) and 21.8% (no AC, p<0.001) in stage III disease, respectively. Among 460 patients undergoing AC, AC was initiated within 8 weeks in 438 patients (95.2%) and after 8 weeks in 22 patients (4.8%). Factors affecting AC delay were male gender, rectal primary, intraoperative blood loss (>100ml), and presence of postoperative complications. Overall survival was 90.8% (AC +) and 40.0% (no AC, p=0.111) in stage II disease, and 82% (AC +) and 35.6% (no AC, p=0.275) in stage III disease, respectively. Recurrence-free survival 80.1% (AC +) and 54.5% (no AC, p=0.133) in stage II disease, and 64.4% (AC +) and 0.0% (no AC, p=0.014), respectively. Conclusions: In stage II, III patients, it appears that use of AC is more closely related patient’s survival rather than the time of AC initiation. To improve oncologic outcomes after curative resection, it is important to increase the proporation of AC use.

SP4.2.12 The impact of COVID 19 on colorectal cancer diagnosis and surgical oncological provision; A national perspective

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Noel Donlon ◽  
Tim Nugent ◽  
Shane Irwin ◽  
SInead Ramjit ◽  
Maria Davern ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
National Level ◽  
Late Presentation ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Admission Rates ◽  
Cancer Management ◽  
National Quality ◽  
National Perspective ◽  
The Impact

Abstract Introduction The COVID-19 pandemic has interfered with many aspects of cancer management, including delayed diagnoses, stalled screening programmes, limiting treatment and clinical trials. Colorectal cancer is the second commonest cause of cancer death in Ireland. The objective of the current study is to assess the impact of this pandemic on colorectal cancer diagnoses and surgery, at a national level. Methods Data on endoscopy, emergency and elective colorectal operations nationally in Ireland over a three year period (2018-2020) were obtained from the National Quality Assurance Improvement System. Data relating to cancer surgery only were included and patient demographics, type of surgery (open/laparoscopic), length of stay (LOS), mortality, admission to critical care and re-admission rates were collected and analysed. Results 31.33% less cancers have been diagnosed between March and November 2020 inclusive when compared to the same period over the past two years with 22% less rectal cancers identified. There has been a 34% reduction in colorectal cancer surgeries over the same period with a reduction of 42% at the initial wave during the period March-May and of concern, this trend has continued. Laparoscopic right hemicolectomies have reduced by 41%, anterior resections have reduced by 51% with no change in the number of temporary ileostomies over the three year period. Conclusion The impact of COVID-19 on colorectal cancer surgery nationally has been profound. The reduction in diagnoses and cancer surgery is concerning and may result in increased late or incurable stage disease as a consequence of late presentation and diagnosis.

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