scholarly journals Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission - confounded by the gut microbiome? Authors’ reply

2019 ◽  
Vol 49 (8) ◽  
pp. 1088-1089
Author(s):  
Ammar Hassanzadeh Keshteli ◽  
Karen L. Madsen ◽  
Rupasri Mandal ◽  
Guy E. Boeckxstaens ◽  
Premysl Bercik ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Gut Microbiome ◽  
Clinical Remission ◽  
Colorectal Adenocarcinoma ◽  
Irritable Bowel

scholarly journals Irritable bowel syndrome-like symptoms associated with endoscopic activity predict ulcerative colitis relapse in patients with clinical remission

2017 ◽  
Vol 15 (4) ◽  
pp. 543 ◽  
Author(s):  
Nobuhiko Fukuba ◽  
Shunji Ishihara ◽  
Kousaku Kawashima ◽  
Yoshiyuki Mishima ◽  
Naoki Oshima ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Clinical Remission ◽  
Irritable Bowel

scholarly journals Taxonomic composition and biodiversity of the gut microbiome from patients with irritable bowel syndrome, ulcerative colitis, and asthma

2022 ◽  
Vol 25 (8) ◽  
pp. 864-873
Author(s):  
A. Y. Tikunov ◽  
A. N. Shvalov ◽  
V. V. Morozov ◽  
I. V. Babkin ◽  
G. V. Seledtsova ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Gut Microbiota ◽  
Gut Microbiome ◽  
Taxonomic Composition ◽  
16S Rrna Genes ◽  
Rrna Genes ◽  
Taxonomic Structure ◽  
Opportunistic Bacteria ◽  
Irritable Bowel

To date, the association of an imbalance of the intestinal microbiota with various human diseases, including both diseases of the gastrointestinal tract and disorders of the immune system, has been shown. However, despite the huge amount of accumulated data, many key questions still remain unanswered. Given limited data on the composition of the gut microbiota in patients with ulcerative colitis (UC) and irritable bowel syndrome (IBS) from different parts of Siberia, as well as the lack of data on the gut microbiota of patients with bronchial asthma (BA), the aim of the study was to assess the biodiversity of the gut microbiota of patients with IBS, UC and BA in comparison with those of healthy volunteers (HV). In this study, a comparative assessment of the biodiversity and taxonomic structure of gut microbiome was conducted based on the sequencing of 16S rRNA genes obtained from fecal samples of patients with IBS, UC, BA and volunteers. Sequences of the Firmicutes and Bacteroidetes types dominated in all samples studied. The third most common in all samples were sequences of the Proteobacteria type, which contains pathogenic and opportunistic bacteria. Sequences of the Actinobacteria type were, on average, the fourth most common. The results showed the presence of dysbiosis in the samples from patients compared to the sample from HVs. The ratio of Firmicutes/Bacteroidetes was lower in the IBS and UC samples than in HV and higher the BA samples. In the samples from patients with intestinal diseases (IBS and UC), an increase in the proportion of sequences of the Bacteroidetes type and a decrease in the proportion of sequences of the Clostridia class, as well as the Ruminococcaceae, but not Erysipelotrichaceae family, were found. The IBS, UC, and BA samples had signif icantly more Proteobacteria sequences, including Methylobacterium, Sphingomonas, Parasutterella, Halomonas, Vibrio, as well as Escherichia spp. and Shigella spp. In the gut microbiota of adults with BA, a decrease in the proportion of Roseburia, Lachnospira, Veillonella sequences was detected, but the share of Faecalibacterium and Lactobacillus sequences was the same as in healthy individuals. A signif icant increase in the proportion of Halomonas and Vibrio sequences in the gut microbiota in patients with BA has been described for the f irst time.

scholarly journals Irritable Bowel Syndrome-Like Symptoms in Ulcerative Colitis Patients in Clinical Remission: Association with Residual Colonic Inflammation

Digestion ◽  
2018 ◽  
Vol 99 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Shunji Ishihara ◽  
Kousaku Kawashima ◽  
Nobuhiko Fukuba ◽  
Yasumasa Tada ◽  
Satoshi Kotani ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Clinical Remission ◽  
Colonic Inflammation ◽  
Irritable Bowel

Prevalence of functional dyspepsia-like symptoms in ulcerative colitis patients in clinical remission and overlap with irritable bowel syndrome-like symptoms

2020 ◽  
Vol 55 (5) ◽  
pp. 560-564
Author(s):  
Satoshi Kotani ◽  
Nobuhiko Fukuba ◽  
Kousaku Kawashima ◽  
Yoshiyuki Mishima ◽  
Hiroki Sonoyama ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Functional Dyspepsia ◽  
Clinical Remission ◽  
Irritable Bowel

scholarly journals IBS-Symptoms in IBD Patients—Manifestation of Concomitant or Different Entities

2020 ◽  
Vol 10 (1) ◽  
pp. 31
Author(s):  
Patrycja Szałwińska ◽  
Jakub Włodarczyk ◽  
Antonino Spinelli ◽  
Jakub Fichna ◽  
Marcin Włodarczyk
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Crohn’S Disease ◽  
Abdominal Pain ◽  
Inflammatory Bowel Diseases ◽  
Clinical Remission ◽  
Gut Motility ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Irritable Bowel

Irritable bowel syndrome (IBS) is a functional heterogenous disease with a multifactorial pathogenesis. It is characterized by abdominal pain, discomfort, and alteration in gut motility. The occurrence of similar symptoms was observed in patients in clinical remission of inflammatory bowel diseases (IBD) that is Crohn’s disease (CD) and ulcerative colitis (UC), which pathogenesis is also not fully understood. Hence, arose the question if these symptoms are “true IBS” imposed on IBD, or is it a subclinical form of IBD or even pre-IBD? In this article, based on a narrative overview of the literature, we try to find an answer to this query by discussing the pathogenesis and overlaps between these conditions.

Gut permeability in patients with irritable bowel syndrome and inactive ulcerative colitis

2009 ◽  
Vol 47 (05) ◽  
Author(s):  
K Gecse ◽  
R Róka ◽  
T Séra ◽  
A Annaházi ◽  
A Rosztóczy ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Gut Permeability ◽  
Irritable Bowel

Distinct Microbial Populations Exist in the Mucosa-associated Microbiota of Diarrhea Predominant Irritable Bowel Syndrome and Ulcerative Colitis

2019 ◽  
Vol 53 (9) ◽  
pp. 660-672 ◽  
Author(s):  
Wenting Zhong ◽  
Xiaolan Lu ◽  
Haitao Shi ◽  
Gang Zhao ◽  
Yahua Song ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Irritable Bowel Syndrome ◽  
Microbial Populations ◽  
Irritable Bowel
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