scholarly journals Investigating human eyelash hair follicle growth in situ and ex vivo : a pilot study

2020 ◽  
Author(s):  
C.I. Platt ◽  
J. Laybourne ◽  
P. Cannon ◽  
R. Paus
Keyword(s):  
Pilot Study ◽  
Hair Follicle ◽  
Ex Vivo ◽  
Follicle Growth ◽  
Hair Follicle Growth

scholarly journals Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo

2018 ◽  
Vol 138 (6) ◽  
pp. 1420-1422 ◽  
Author(s):  
Iain S Haslam ◽  
Jonathan A Hardman ◽  
Ralf Paus
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Ex Vivo ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Hair Follicle Growth

scholarly journals Sustained Human Hair Follicle Growth Ex Vivo in a Glycosaminoglycan Hydrogel Matrix

2019 ◽  
Vol 20 (7) ◽  
pp. 1741 ◽  
Author(s):  
Sandra Fernández-Martos ◽  
María Calvo-Sánchez ◽  
Karla García-Alonso ◽  
Begoña Castro ◽  
Bita Hashtroody ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Wound Repair ◽  
Ex Vivo ◽  
Hair Follicles ◽  
Stem Cell Markers ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Hydrogel Matrix ◽  
Hair Follicle Growth

Glycosaminoglycans (GAGs) and associated proteoglycans have important functions in homeostatic maintenance and regenerative processes (e.g., wound repair) of the skin. However, little is known about the role of these molecules in the regulation of the hair follicle cycle. Here we report that growing human hair follicles ex vivo in a defined GAG hydrogel mimicking the dermal matrix strongly promotes sustained cell survival and maintenance of a highly proliferative phenotype in the hair bulb and suprabulbar regions. This significant effect is associated with the activation of WNT/β-catenin signaling targets (CCDN1, AXIN2) and with the expression of stem cell markers (CK15, CD34) and growth factors implicated in the telogen/anagen transition (TGFβ2, FGF10). As a whole, these results point to the dermal GAG matrix as an important component in the regulation of the human hair follicle growth cycle, and to GAG-based hydrogels as potentially relevant modulators of this process both in vitro and in vivo.

ANXA1 affects murine hair follicle growth through EGF signaling pathway

Gene ◽  
2021 ◽  
Vol 771 ◽  
pp. 145343
Author(s):  
Hao Zhang ◽  
Xiaoqiao Fu ◽  
Yue Ao ◽  
Miaomiao Nan ◽  
Ziyu Qiu ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Signaling Pathway ◽  
Follicle Growth ◽  
Hair Follicle Growth ◽  
Egf Signaling

Control of the hair follicle growth cycle

2000 ◽  
pp. 83-94
Author(s):  
Ralf Paus ◽  
Sven Müller-Röver ◽  
Ian McKay
Keyword(s):  
Hair Follicle ◽  
Growth Cycle ◽  
Follicle Growth ◽  
Hair Follicle Growth

Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells

2017 ◽  
Vol 42 (3) ◽  
pp. 287-294 ◽  
Author(s):  
Y.-S. Su ◽  
Z.-X. Fan ◽  
S.-E. Xiao ◽  
B.-J. Lin ◽  
Y. Miao ◽  
...  
Keyword(s):  
Growth Factor ◽  
Hair Follicle ◽  
Insulin Like Growth Factor ◽  
Follicle Growth ◽  
Hair Follicle Growth
Sign in / Sign up

Export Citation Format

Share Document