scholarly journals Diagnosis and treatment of chronic synovitis in patients with haemophilia: consensus statements from the Italian Association of Haemophilia Centres

Author(s):  
Matteo Nicola Dario Di Minno ◽  
Mariasanta Napolitano ◽  
Anna Chiara Giuffrida ◽  
Erminia Baldacci ◽  
Christian Carulli ◽  
...  
2016 ◽  
Vol 31 (9) ◽  
pp. 1546-1554 ◽  
Author(s):  
Hiroyuki Isayama ◽  
Yousuke Nakai ◽  
Rungsun Rerknimitr ◽  
Christopher Khor ◽  
James Lau ◽  
...  

2015 ◽  
Vol 4 (2) ◽  
pp. 190-202 ◽  
Author(s):  
Michael J. McNamee ◽  
Bradley Partridge ◽  
Lynley Anderson

The issue of concussion in sport is a matter of global public interest that is currently under dispute by educational, legal, and medical professionals and scientists. In this article we discuss the problem from philosophical, bioethical, and sports ethical perspectives. We articulate conceptual differences in approaches to definition and therefore diagnosis of concussion. We critically review similarities and differences in the leading consensus statements that guide the treatment of concussion diagnosis and treatment in sports. We then present a series of ethical problems including issues that relate to paternalistic intervention in the lives of athletes in order to prevent harm to athletes, conflicting and competing interests, and confidentiality.


BMC Medicine ◽  
2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Evi V Nagler ◽  
Jill Vanmassenhove ◽  
Sabine N van der Veer ◽  
Ionut Nistor ◽  
Wim Van Biesen ◽  
...  

2007 ◽  
Vol 31 (6) ◽  
pp. 727-736 ◽  
Author(s):  
Peter Valent ◽  
Hans-Peter Horny ◽  
John M. Bennett ◽  
Christa Fonatsch ◽  
Ulrich Germing ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Ya-Xin Chen ◽  
Ning Liang ◽  
Xiao-Ling Li ◽  
Si-Hong Yang ◽  
Yan-Ping Wang ◽  
...  

Background: Mild cognitive impairment (MCI) is an important stage between the normal cognitive decline of aging and dementia. The aim of this study was to compare and harmonize the recommendations for the diagnosis and treatment of MCI based on current clinical practice guidelines.Methods: We searched the PubMed, EMBASE, China National Knowledge Infrastructure, Wanfang Database, Chinese Science and Technology Periodical Database, and Chinese Biological Medicine Database from their inception date to April 24, 2021 to identify all published guidelines on MCI. The qualities of the eligible guidelines were appraised by two reviewers using the Appraisal of Guidelines for Research and Evaluation II instrument.Results: Thirteen guidance documents (four guidelines and nine consensus statements) with specific recommendations were included. Nine guidelines and consensus statements covered the screening and diagnosis of MCI. The evaluation of the documents showed that neuropsychological testing and biomarker assessments were the most common recommendations for the diagnosis of MCI. Nine of the 13 guidance documents covered the treatment and management of MCI. The recommendations for the treatment and management were classified into four categories, namely: intervention for risk reduction, pharmacologic interventions, non-pharmacologic interventions, and counseling. Regarding pharmacological interventions, three guidelines recommend no pharmacologic intervention. The use of cholinesterase inhibitors for MCI is contraindicated in three guidance documents, whereas one proposes that cholinesterase inhibitors and memantine should be deprescribed. EHb761®, Chinese herbal decoctions, and Chinese traditional patent medicine are recommended in two documents. A total of seven guidance documents recommend non-pharmacological interventions, including physical activity interventions, cognitive interventions, dietary and nutritional interventions, and acupuncture.Conclusion: An updated search for possible evidence on the diagnosis and treatment of MCI is needed. Potentially effective diagnoses and treatments, either conventional or complementary, and alternative therapies should be highly valued and addressed in correlation with the supporting evidence.


2018 ◽  
Vol 7 (2) ◽  
pp. 27-32
Author(s):  
Anna Zakrzewska

Pediatric rhinosinusitis is defined as a presence of two or more symptoms and one of them should be either nasal blockage or nasal discharge and headache/facial pain or cough. Chronic rhinosinusitis - CRS is recognized when the four most common symptoms as cough, rhinorrhea, nasal congestion and post nasal drip with a slightly higher predominance of chronic cough are presented for more than 12 weeks and influence the quality of life. CRS should be considered in respect of unique conditions because of the differences in predisposing factors (immunological and others) and the anatomy of the sinuses between children and adults. The adenoids are a prominent contributor to CRS in young children, both from bacteriologic and immunologic status. The older children suffer from CRS in the same manner as adults. During evaluation a child with symptoms of CRS , one should always consider the possibility of underlying disease as a contributing factor. Diseases impacting sinuses and nasal function include CF, primary ciliary dyskinesia (PCD) and a variety of normal immune deficiencies, including the still-developing immature immunity of healthy young children. Surgical intervention for rhinosinusitis is usually considered for patients with CRS who have failed maximal pharmacological treatment. There are two important consensus statements for pediatric chronic sinusitis (CRS): European Position papers on Rhinosinusitis and Nasal Polyps -EPOS 2012 and Clinical Consensus Statement: Pediatric Chronic Sinusitis American Academy Otolaryngology-Head Neck Surgery 2014. Both of them contain necessary information and recommendation for diagnosis and treatment of CRS in children.


2008 ◽  
Vol 40 (10) ◽  
pp. 803-808 ◽  
Author(s):  
R. Pezzilli ◽  
G. Uomo ◽  
A. Zerbi ◽  
A. Gabbrielli ◽  
L. Frulloni ◽  
...  

2019 ◽  
Vol 4 ◽  
pp. 181 ◽  
Author(s):  
James A Seddon ◽  
Guy E Thwaites ◽  

Tuberculous meningitis is the most severe form of tuberculosis and causes widespread mortality and morbidity. Understanding of the epidemiology and pathogenesis is incomplete, and the optimal diagnosis and treatment are poorly defined. To generate research collaboration and coordination, as well as to promote sharing of ideas and advocacy efforts, the International Tuberculous Meningitis Research Consortium was formed in 2009. During the most recent meeting of this group in Lucknow, India, in March 2019, the Consortium decided to bring together key articles on tuberculous meningitis in one supplement. The supplement covers recent scientific updates, expert perspectives on specific clinical challenges, consensus statements on how to conduct research, and a set of priorities for future investigation.


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