Ocular coherence tomography‐measured changes over time in anterior chamber angle and diurnal intraocular pressure after laser iridotomy: IMPACT study

Aim. To study the changes of anatomic and topographic characteristics of the eye anterior segment after uncomplicated cataract phacoemulsification using corneal incision with intraocular soft lens implantation. Methods. The data of ultrasound biomicroscopy and noncontact tonometry of 58 eyes (56 patients, 32 females, 24 males aged 54 to 78 years) before and after cataract phacoemulsification were analyzed. Paitents with survived ocular trauma, refractive keratoplasty, glaucoma, uveitis, and surgical complications (incomplete capsulorrhexis, posterior capsule rupture, ciliary zonule disinsertion, corneal burn). Apart from the common examinations (visual acuity testing, tonometry, tonography, eye A- and B-ultrasonography, biomicroscopy), all patients underwent eye ultrasound biomicroscopy. Results. Anterior chamber depth increased from 2.73±0.10 to 4.17±0.06 mm (p ≤0.001). Trabecula-iris distance measured at 500 μm from the scleral spur, increased from 0.38±0.02 to 0.47±0.02 mm (p ≤0.001). Anterior chamber angle increased from 28.69±1.87 to 42.73±1.56 degrees (p ≤0.001), the angle between the iris and the sclera increased from 32.78±1.39 to 41.36±0.84 degrees (p ≤0.001), the angle between the sclera and ciliary processes increased from 39.48±1.29 to 45.30±1.16 degrees (p ≤0.001). Intraocular pressure according to the non-contact tonometry data decreased from 18.16±1.29 to 13.55±0.95 mm Hg (p ≤0.001). Conclusion. Anterior chamber depth, trabecula-iris distance, anterior chamber angle, the angle between sclera and iris and the angle between sclera and ciliary processes increased significantly after phacoemulsification with intraocular lens implantation. Intraocular pressure decreased significantly according to the non-contact tonometry data.

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Understanding Trabecular Meshwork Physiology: A Key to the Control of Intraocular Pressure?

Physiology ◽

10.1152/nips.01443.2003 ◽

2003 ◽

Vol 18 (5) ◽

pp. 205-209 ◽

Cited By ~ 10

Author(s):

Artur Llobet ◽

Xavier Gasull ◽

Arcadi Gual

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Aqueous Humor ◽

Trabecular Meshwork ◽

Anterior Chamber Angle ◽

Chamber Angle

The trabecular meshwork is a tissue located in the anterior chamber angle of the eye, and it is a crucial determinant of intraocular pressure values because of its resistance to the evacuation of aqueous humor from the eye. Here we bring together classical and recent discoveries on the function of the trabecular meshwork, keys to understanding eye pathophysiology.

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Anterior Chamber Angle and Iris-Lens Contact Alteration During Pupillary Dilation

ASME 2011 Summer Bioengineering Conference, Parts A and B ◽

10.1115/sbc2011-53643 ◽

2011 ◽

Author(s):

Sara Jouzdani ◽

Rouzbeh Amini ◽

Victor H. Barocas

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Aqueous Humor ◽

Ciliary Body ◽

Ocular Tissue ◽

Posterior Chamber ◽

Pupillary Dilation ◽

Anterior Chamber Angle ◽

Aqueous Outflow ◽

Chamber Angle

The aqueous humor (AH) provides oxygen and nutrients for the avascular ocular tissue specifically, the cornea and lens. AH is secreted by the ciliary body into the posterior chamber, passes through pupil, and drains into the anterior chamber (Fig. 1a). Resistance to the aqueous outflow generates the intraocular pressure (IOP), which is 15–20 mmHg in the normal eyes.

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ARGON LASER TREATMENT OF THE ANTERIOR CHAMBER ANGLE FOR INCREASED INTRAOCULAR PRESSURE

Acta Ophthalmologica ◽

10.1111/j.1755-3768.1981.tb02981.x ◽

2009 ◽

Vol 59 (2) ◽

pp. 211-220 ◽

Cited By ~ 38

Author(s):

PEKKA POHJANPELTO

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Laser Treatment ◽

Argon Laser ◽

Anterior Chamber Angle ◽

Chamber Angle

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Anterior Chamber Angle Evaluation following Phakic Posterior Chamber Collamer Lens with CentraFLOW and Its Correlation with ICL Vault and Intraocular Pressure

Journal of Ophthalmology ◽

10.1155/2016/1383289 ◽

2016 ◽

Vol 2016 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

Sherif A. Eissa ◽

Sherin H. Sadek ◽

Mohamed W. A. El-Deeb

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Refractive Error ◽

Case Series ◽

Mean Value ◽

Posterior Chamber ◽

Anterior Chamber Angle ◽

Implantable Collamer Lens ◽

Angle Width ◽

Chamber Angle

Purpose.To assess intraocular pressure (IOP), lens vaulting, and anterior chamber (AC) angle width, following V4C implantable Collamer lens (ICL) procedure for myopic refractive error.Methods.A prospective case series that enrolled 54 eyes of 27 patients that were evaluated before and after V4C phakic posterior chamber Collamer lens implantation for correction of myopic refractive error. Preoperative measurement of IOP was done using Goldmann applanation tonometer and anterior chamber angle width using both Van Herick slit lamp grading system and Scheimpflug tomography imaging (Oculus Pentacam). Follow-up of the aforementioned variables was at 1, 6, and 18 months postoperatively, together with ICL vault measurements.Results.The mean baseline IOP of11.69±2.15showed a statistically significant (P=0.002) increase after 1 month that remained unchanged at 6 and 18 months postoperatively, with mean value of16.07±4.12,16.07±4.10, and16.07±4.13, respectively. Pentacam AC angle width showed a statistically significant decrease at 1(P=0.025), 6(P=0.016), and 18(P=0.010)months postoperatively, with mean preoperative value of40.14±5.49that decreased to25.28±5.33,25.46±5.44, and25.49±5.38, at 1, 6, and 18 months, respectively. Mean ICL vault showed moderate correlation with Pentacam AC angle width at 1(r=-0.435)and 6(r=-0.424)months.Conclusion. V4C ICL implantation resulted in decrease in AC angle width and increase in IOP, within acceptable physiological values at all time points.

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Assessment of anterior chamber angle changes after phacoemulsification with swept-source OCT

International Journal of Ophthalmology ◽

10.18240/ijo.2021.10.08 ◽

2021 ◽

Vol 14 (10) ◽

pp. 1527-1532

Author(s):

Qian Zheng ◽

◽

Zhang-Liang Li ◽

Ping-Jun Chang ◽

Yun-E Zhao ◽

...

Keyword(s):

Intraocular Pressure ◽

Cataract Surgery ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Anterior Chamber Angle ◽

Swept Source ◽

Narrow Angle ◽

Significant Difference ◽

Shallow Anterior Chamber ◽

Chamber Angle

AIM: To assess the changes of anterior chamber angle in patients with shallow anterior chamber after phacoemulsification combined with intraocular lens (IOL) implantation, based on anterior segment swept-source optical coherence tomography (AS-SS-OCT) measurements. METHODS: This was a prospective case control study; sixty eyes of sixty case were scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were divided into two groups: group of shallow anterior chamber and narrow angle (SAC group, 30 eyes); and group of normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), iris volume (IV), lens vault (LV), angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3mo after surgery. RESULTS: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, intraocular pressure, and IV between two groups before surgery, except for the LV (P=0.000). ACD and ACV were prominently larger in the NAC group than the SAC group 3mo after operation (3.69±0.38 vs 3.85±0.39 mm, P=0.025; 161.37±19.47 vs 178.26±20.30 mm3, P=0.002). AOD750, ARA750 in nasal and inferior quadrants, TISA750 in all quadrants except temporal, and TIA750 in all quadrants in SAC group were significantly smaller than those in NAC group after operation (all P<0.05). CONCLUSION: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the angle related parameters including AOD750, ARA750, TISA750, TIA, TISA750, and ACV in patients with shallow anterior chamber and narrow angle do not reach the normal level.

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INTRAVITREAL INTRODUCTION OF LUCENTIS AND TRANS-SCLERAL CYCLOPHOTOCOAGULATION IN THE TREATMENT OF NEOVASCULAR GLAUCOMA IN DIABETES MELLITUS

Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук ◽

10.12737/23792 ◽

2016 ◽

Vol 1 (6) ◽

pp. 122-124

Author(s):

Ефремова ◽

Tatyana Efremova ◽

Балалин ◽

Sergey Balalin ◽

Фокин ◽

...

Keyword(s):

Visual Acuity ◽

Intraocular Pressure ◽

Anterior Chamber ◽

Laser Surgery ◽

Neovascular Glaucoma ◽

Mean Value ◽

Anterior Chamber Angle ◽

Second Stage ◽

Anti Vegf ◽

Chamber Angle

We analyzed the results of surgical treatment of 42patients (42eyes) with neovascular glaucoma on the background of proliferative diabetic retinopathy. Intravitreal injections of anti-VEGF-drugs allow to remove newly formed vessels in anterior chamber angle, to reduce intraocular pressure, to avoid complications in patients with neovascular glaucoma and the closed anterior chamber angle of the eye. The second stage of the treatment can be laser surgery. This approach helped to reduce intraocular pressure from 28.9±0.9 to 18.5±0.9mmHg on the background of medical treatment (t>2.0; p<0.05). Visual acuity increased from 0.23±0.07 to 0.44±0.08 (t>2.0; p<0.05).In patients with NVG and closed anterior chamber angle of the eye, having aching glaucoma the use of laser surgery as the first stage of treatment allows to reduce intraocular pressure and to eliminate pain, and to apply intravitreal anti-VEGF-therapy as the second stage. The mean value of IOP decreased from 30.9±1.2 to 20.1±1.1mmHg. During the year period, the second stage (intravitreal introduction of Lucentis) was performed in all patients. As a result, IOP was reduced to 17.5±0.09mmHg. Visual acuity increased from 0.18±0.1 to 0.25±0.07 (p>0.05).

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