The changes of anatomic and topographic characteristics of eye anterior segment after uncomplicated cataract phacoemulsification

Aim. To study the changes of anatomic and topographic characteristics of the eye anterior segment after uncomplicated cataract phacoemulsification using corneal incision with intraocular soft lens implantation. Methods. The data of ultrasound biomicroscopy and noncontact tonometry of 58 eyes (56 patients, 32 females, 24 males aged 54 to 78 years) before and after cataract phacoemulsification were analyzed. Paitents with survived ocular trauma, refractive keratoplasty, glaucoma, uveitis, and surgical complications (incomplete capsulorrhexis, posterior capsule rupture, ciliary zonule disinsertion, corneal burn). Apart from the common examinations (visual acuity testing, tonometry, tonography, eye A- and B-ultrasonography, biomicroscopy), all patients underwent eye ultrasound biomicroscopy. Results. Anterior chamber depth increased from 2.73±0.10 to 4.17±0.06 mm (p ≤0.001). Trabecula-iris distance measured at 500 μm from the scleral spur, increased from 0.38±0.02 to 0.47±0.02 mm (p ≤0.001). Anterior chamber angle increased from 28.69±1.87 to 42.73±1.56 degrees (p ≤0.001), the angle between the iris and the sclera increased from 32.78±1.39 to 41.36±0.84 degrees (p ≤0.001), the angle between the sclera and ciliary processes increased from 39.48±1.29 to 45.30±1.16 degrees (p ≤0.001). Intraocular pressure according to the non-contact tonometry data decreased from 18.16±1.29 to 13.55±0.95 mm Hg (p ≤0.001). Conclusion. Anterior chamber depth, trabecula-iris distance, anterior chamber angle, the angle between sclera and iris and the angle between sclera and ciliary processes increased significantly after phacoemulsification with intraocular lens implantation. Intraocular pressure decreased significantly according to the non-contact tonometry data.

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Diagnostic Value of Modern Methods of Ocular Anterior Segment Visualization in Intumescent Cataract

Ophthalmology in Russia ◽

10.18008/1816-5095-2019-3-350-354 ◽

2019 ◽

Vol 16 (3) ◽

pp. 350-354

Author(s):

O. L. Fabrikantov ◽

S. I. Nikolashin ◽

E. S. Pirogova

Keyword(s):

Anterior Chamber ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Ultrasound Biomicroscopy ◽

Diagnostic Value ◽

Ligament Length ◽

Anterior Chamber Angle ◽

Lens Thickness ◽

Scheimpflug Camera ◽

Chamber Angle

Purpose: tо evaluate the diagnostic capabilities of optical coherence tomography (OCT), Scheimpflug camera and ultrasound biomicroscopy (UBM) in examining topography of the ocular anterior segment and lens in mature intumescent cataract. Patients and methods. 23 eyes with mature intumescent cataract were examined using OCT (RTVue-100, Optovue, USA), Scheimpflug camera (Pentacam HR, Oculus, Germany) and UBM (UD 8000, Tomey, Japan). We examined the anterior chamber depth, profile and magnitude of the anterior chamber angle, distance “trabecula-iris at 500 microns”, thickness of the liquid lenticular mass layer, lens thickness, Zinn ligament length within four segments, equatorial angle. Results. We managed to measure the anterior chamber depth using UBM and Scheimpflug camera. UBM measurement was 1.96 ± 0.14 mm, Scheimpflug camera — 1.91 ± 0.11 mm. We revealed narrowing of the anterior chamber angle up to 11.54 ± 2.19° in UMB examination, to 11.49 ± 2.17° in OCT measuring and to 11.63 ± 2.21° in examining by Scheimpflug camera. Distance “trabecula-iris 500” was 0.212 ± 0.037 mm in UMB examination, 0.218 ± 0.042 mm — by means of OCT, Scheimpflug camera measurement was unsuccessful. The rest parameters were examined only by UBM. The lens thickness was 5.26 ± 0.13 mm. The anterior layer of liquid lenticular mass was 0.85 ± 0.06 mm. Zinn ligament length in the outer segment was 0.708 ± 0.072 mm, in the internal segment — 0.731 ± 0.089 mm, in the superior segment — 0.704 ± 0.084 mm, in the inferior segment — 0.876 ± 0.089 mm. The equatorial angle in two opposite segments was 32.52 ± 0.92°. Conclusion. Ultrasound biomicroscopy has the biggest value in examining topography of the ocular anterior segment and lens in mature intumescent cataract, since only this method allows achieving the whole complex of data necessary to evaluate the swelling lens parameters. This can serve as a basis for developing the appropriate tactics of surgical intervention.

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Anterior Chamber Angle and Volume Do Not Change after Myopic Laser-Assisted In Situ Keratomileusis in Young Patients

Journal of Ophthalmology ◽

10.1155/2018/8646275 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4

Author(s):

Ertuğrul Tan Yassa ◽

Cihan Ünlü

Keyword(s):

Anterior Chamber ◽

Anterior Segment ◽

Young Patients ◽

Anterior Chamber Depth ◽

Ablation Depth ◽

Anterior Chamber Angle ◽

Chamber Volume ◽

The Mean ◽

Chamber Angle

Purpose. We aimed to investigate whether anterior chamber angle, depth, and volume change after myopic laser-assisted in situ keratomileusis (LASIK) in young patients. Methods. This retrospective study included 29 eyes of 29 patients (15 females and 14 males) between the ages of 18 and 39 years who underwent LASIK for the treatment of myopia. In addition to complete ophthalmic examination, anterior chamber angle (ACA), central anterior chamber depth (ACD), and anterior chamber volume (ACV) were measured by using a Sirius rotating Scheimpflug camera combined with Placido disc corneal topography (CSO, Florence, Italy). Preoperative and postoperative values were compared using paired t-tests. Linear regression was used to evaluate the relationship between changes in refraction and changes in ACA, ACD, and ACV as well as between attempted maximum ablation depth and changes in ACA, ACD, and ACV. Results. The mean age of the study population was 25.5 ± 6.2 years. The mean preoperative and postoperative spherical equivalent values were −3.30 ± 1.92 D and −0.18 ± 0.29 D, respectively. ACV and ACA were not significantly changed after surgery; however, central ACD was significantly decreased (preoperatively = 3.366 ± 0.316 mm vs postoperatively = 3.3 ± 0.298 mm) with a mean difference of 0.066 ± 1.121 mm. There were no significant relationships between changes in refraction and anterior segment dimensions or between attempted maximum ablation depth and anterior segment dimensions. Conclusion. Measurements with Sirius showed that ACA and ACV did not change; however, central ACD significantly decreased after myopic LASIK in young patients, indicating that the preoperative central ACD value should not be used interchangeably with the postoperative central ACD value.

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Anterior chamber angle imaging with swept-source optical coherence tomography: comparison between CASIAII and ANTERION

Scientific Reports ◽

10.1038/s41598-020-74813-3 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Poemen Pui-man Chan ◽

Gilda Lai ◽

Vivian Chiu ◽

Anita Chong ◽

Marco Yu ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Angle Closure ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Scan Pattern ◽

Chamber Angle

Abstract This study compared the test–retest variabilities and measurement agreement of anterior chamber angle (ACA) dimensions measured by two anterior segment swept-source optical coherence tomography (SS-OCT)—the ANTERION (Heidelberg Engineering, Heidelberg, Germany) and CASIAII (Tomey, Nagoya, Japan). Thirty-eight subjects, 18 patients with primary angle closure and 20 healthy participants with open angles, were included. The mean age was 54.7 ± 15.8 years (range: 26–75 years). One eye of each subject was randomly selected for anterior segment imaging by ANTERION and CASIAII, using the same scan pattern (6 evenly spaced radial scans across the anterior segment for three times) in the same visit. The between- and within-instrument agreement and repeatability coefficients of angle open distance (AOD500), trabecular-iris space area (TISA500), lens vault (LV), scleral spur-scleral spur distance (SSD), anterior chamber depth (ACD), and pupil diameter (PD) were measured. The anterior and posterior boundaries of the cornea, iris, and lens were automatically segmented by the SS-OCT instruments; the scleral spur was manually located by a single masked observer. There were significant differences between ANTERION and CASIAII measurements; the SSD, PD, and ACD were smaller whereas AOD500 and TISA500 were greater in ANTERION compared with CASIAII (P < 0.001). Anterior segment measurements obtained from the two SS-OCT instruments showed strong associations (R2 ranged between 0.866 and 0.998) although the between-instrument agreement was poor; the spans of 95% limits of between-instrument agreement were ≥ 1.5-folds than the within-instrument agreement for either instrument. Whereas both SS-OCT instruments showed low test–retest measurement variabilities, the repeatability coefficients of AOD500, TISA500, ACD, and PD were slightly smaller for CASIAII than ANTERION (P ≤ 0.012).

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Changing Trends of Imaging in Angle Closure Evaluation

ISRN Ophthalmology ◽

10.5402/2012/597124 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Syril Dorairaj ◽

James C. Tsai ◽

Tomas M. Grippo

Keyword(s):

Optical Coherence Tomography ◽

High Resolution ◽

Anterior Chamber ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Infrared Light ◽

Angle Closure ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Chamber Angle

Primary angle closure glaucoma (PACG) is a significant cause of visual disability worldwide. It predominantly affects the Eastern and South Asian population of the world. Early detection of anatomically narrow angles is important, and the subsequent prevention of visual loss from PACG depends on an accurate assessment of the anterior chamber angle (ACA). Gonioscopy has given way to modern day imaging technologies such as ultrasound biomicroscopy (UBM) and more recently, anterior segment optical coherence tomography (AS-OCT). Ultrasound biomicroscopy provides objective, high-resolution images of anterior segment anatomy, including the cornea, iris, anterior chamber, anterior chamber angle, and ciliary body. Optical coherence tomography (OCT) is a noncontact optical signal acquisition and processing device that provides magnified, high-resolution cross-sectional images of ocular tissues. Recent technological advances towards three-dimensional visualization broadened the scope of AS-OCT in ophthalmologic evaluation. Optical coherence tomography systems use low-coherence, near-infrared light to provide detailed images of anterior segment structures at resolutions exceeding that of UBM. This paper summarizes the clinical application of UBM and OCT for assessment of anterior segment in glaucoma.

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Assessment of anterior chamber angle changes after phacoemulsification with swept-source OCT

International Journal of Ophthalmology ◽

10.18240/ijo.2021.10.08 ◽

2021 ◽

Vol 14 (10) ◽

pp. 1527-1532

Author(s):

Qian Zheng ◽

◽

Zhang-Liang Li ◽

Ping-Jun Chang ◽

Yun-E Zhao ◽

...

Keyword(s):

Intraocular Pressure ◽

Cataract Surgery ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Anterior Chamber Angle ◽

Swept Source ◽

Narrow Angle ◽

Significant Difference ◽

Shallow Anterior Chamber ◽

Chamber Angle

AIM: To assess the changes of anterior chamber angle in patients with shallow anterior chamber after phacoemulsification combined with intraocular lens (IOL) implantation, based on anterior segment swept-source optical coherence tomography (AS-SS-OCT) measurements. METHODS: This was a prospective case control study; sixty eyes of sixty case were scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were divided into two groups: group of shallow anterior chamber and narrow angle (SAC group, 30 eyes); and group of normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), iris volume (IV), lens vault (LV), angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3mo after surgery. RESULTS: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, intraocular pressure, and IV between two groups before surgery, except for the LV (P=0.000). ACD and ACV were prominently larger in the NAC group than the SAC group 3mo after operation (3.69±0.38 vs 3.85±0.39 mm, P=0.025; 161.37±19.47 vs 178.26±20.30 mm3, P=0.002). AOD750, ARA750 in nasal and inferior quadrants, TISA750 in all quadrants except temporal, and TIA750 in all quadrants in SAC group were significantly smaller than those in NAC group after operation (all P<0.05). CONCLUSION: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the angle related parameters including AOD750, ARA750, TISA750, TIA, TISA750, and ACV in patients with shallow anterior chamber and narrow angle do not reach the normal level.

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Comparison of measurements of anterior chamber angle via anterior segment optical coherence tomography and ultrasound biomicroscopy

World Journal of Clinical Cases ◽

10.12998/wjcc.v8.i15.3249 ◽

2020 ◽

Vol 8 (15) ◽

pp. 3249-3258

Author(s):

Zi-Yan Yu ◽

Ting Huang ◽

Lu Lu ◽

Bo Qu

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Chamber Angle

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Evaluation of the Anterior Chamber Angle in Angle-Closure Suspect Patients by Anterior Segment Optical Coherence Tomography (AS-OCT) and Pentacam

10.21203/rs.3.rs-684174/v1 ◽

2021 ◽

Author(s):

Mohamed Salah El-Din Mahmoud ◽

Nosiba Essam ◽

Layla Mohamed Hammouda ◽

Ahmed Shawkat Mohamed

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Angle Closure ◽

P Value ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Cross Sectional ◽

Chamber Angle

Abstract Purpose: The study aims is to detect primary angle-closure glaucoma (PACG) suspects using both anterior segment optical coherence tomography (AS-OCT) and Scheimpflug imaging. Methods: A prospective cross-sectional observational study on forty PACG suspect patients with a range of ages from 20 to 70 years. Angle imaging by AS-OCT (Optovue Inc., Fairmont, CA) with study parameters in the superior, inferior, nasal, and temporal quadrants were anterior chamber angle (ACA), angle opening distance at 750 µm (AOD750), and trabecular-iris space area at 750 μm (TISA). Also, angle imaging using Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany) with study parameters were the anterior chamber angle (ACA), anterior chamber depth (ACD) and, anterior chamber volume (ACV). The angle evaluation was done before and after the mydriatic test.Results: As regarding AS-OCT, after the mydriatic test, we noticed a decrease in all parameters measured, some decreased significantly while others did not. A significant decrease was noticed in ACA (TIA750) in all quadrants (P value<0.001in nasal, 0.001in superior &temporal, 0.003 in inferior) and in TISA750 in the nasal quadrant only (P-value 0.004). AOD750 and TISA750 in the remaining quadrants also decreased but not significantly as ACA. As regarding Pentacam, all parameters decreased after the mydriatic test. ACA (P-value <0.001) and ACD (P-value 0.004) showed significant statistical decrease but ACV showed statistically non-significant decrease (P-value 0.558).Conclusions: AS-OCT and Pentacam are reliable investigations for the detection of PACG suspects which needs more close follow-up for a possible increase in IOP.

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Transient Angle Obstruction Detected by Anterior-Segment Optical Coherence Tomography and Intraocular Pressure Elevation after Hemodialysis

Case Reports in Ophthalmology ◽

10.1159/000513957 ◽

2021 ◽

pp. 761-765

Author(s):

Mihoko Mochiji ◽

Aika Tsutsui ◽

Kaoru Manabe ◽

Masaki Tanito

Keyword(s):

Optical Coherence Tomography ◽

Intraocular Pressure ◽

Anterior Chamber ◽

Anterior Segment ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Blurred Vision ◽

Before And After ◽

Old Japanese ◽

Chamber Angle

An 80-year-old Japanese man presented with decreased vision in his right eye (OD) after every hemodialysis (HD) session beginning several months previously. His local ophthalmologist prescribed antiglaucoma medications because of high intraocular pressure (IOP) (38 mm Hg) OD 4 months previously; with treatment, the IOP fluctuated between 6 and 34 mm Hg OD. When hospitalized, the IOP was measured, and the anterior chamber was observed by anterior-segment optical coherence tomography (AS-OCT) before and after HD. Before HD, the IOP levels were 7 mm Hg OD and 8 mm Hg in the left eye (OS). AS-OCT showed marked anterior iris bowing due to circumferential posterior synechia OD. The scan showed irido-trabecular contact (ITC) in the nasal angle and not the temporal angle OD. Immediately after HD, the IOP levels were 28 mm Hg OD and 12 mm Hg OS; AS-OCT showed ITC in the nasal and temporal angles OD. Since the iris bombe and HD-induced increase in the ITC were expected to have caused the IOP spike and blurred vision, posterior synechialysis and goniosynechialysis were performed OD. Postoperatively, the iris plane flattened; no IOP spike was recorded, and the blurred vision after HD resolved. At 22 months postoperatively, the IOP was 7 mm Hg in both eyes (OU). No deterioration of visual acuity and visual field was recorded during the follow-up period OU. IOP spikes can occur during and after HD because of transient anterior chamber angle obstruction in cases with narrow angles. AS-OCT is useful for detecting minor morphologic changes in the anterior chamber angle during HD.

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Biometric and ICL-related risk factors associated to sub-optimal vaults in eyes implanted with implantable collamer lenses

Eye and Vision ◽

10.1186/s40662-021-00250-6 ◽

2021 ◽

Vol 8 (1) ◽

Author(s):

Santiago Cerpa Manito ◽

Angel Sánchez Trancón ◽

Oscar Torrado Sierra ◽

António Manuel Baptista ◽

Pedro Miguel Serra

Keyword(s):

Risk Factors ◽

Anterior Chamber ◽

Multinomial Logistic Regression ◽

Corneal Thickness ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Anterior Chamber Angle ◽

Factors Associated ◽

Related Risk ◽

Chamber Angle

Abstract Background To identify biometric and implantable collamer lens (ICL)-related risk factors associated with sub-optimal postoperative vault in eyes implanted with phakic ICL. Methods This study reports a retrospective case series of the first operated eye in 360 patients implanted with myopic spherical or toric ICL. Preoperatively, white-to-white (WTW), central keratometry (Kc) and central corneal thickness (CCT) were measured using the Pentacam. Anterior-segment optical coherence tomography (AS-OCT, Visante) was applied preoperatively for measuring the horizontal anterior-chamber angle-to-angle distance (ATA), internal anterior chamber depth (ACD), crystalline lens rise (CLR), anterior-chamber angle (ACA) and postoperatively the vault. Eyes were divided into three vault groups: low (LVG: ≤ 250 μm), optimal (OVG: > 250 and < 1000 μm) and high (HVG: ≥ 1000 μm). Multinomial logistic regression (MLR) was used to find the sub-optimal vault predictors. Results MLR showed that CLR, ICL size minus the ATA (ICL size-ATA), age, ICL spherical equivalent (ICLSE) and ICL size as contributing factors for sub-optimal vaults (pseudo-R2 = 0.40). Increased CLR (OR: 1.01, CI: 1.00–1.01) and less myopic ICLSE (OR: 1.22, CI: 1.07–1.40) were risk factors for low vaults. Larger ICL size-ATA (OR: 41.29, CI: 10.57–161.22) and the 13.7 mm ICL (OR: 7.08, CI: 3.16–15.89) were risk factors for high vaults, whereas less myopic ICLSE (OR: 0.85, CI: 0.76–0.95) and older age (OR: 0.92, CI: 0.88–0.98) were protective factors. Conclusion High CLR and low ICLSE were the major risk factors in eyes presenting low vaults. In the opposite direction, ICL size-ATA was the major contributor for high vaults. This relationship was more critical in higher myopic ICLSE, younger eyes and when 13.7 mm ICL were used. The findings show that factors influencing the vault have differentiated weight of influence depending on the type of vault (low, optimal or high).

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