Titanium implant surface properties enhance osseointegration in ovariectomy induced osteoporotic rats without pharmacologic intervention

This study was carried out to assess the bone response to alkali-modified titanium implant surface (Bio surface), using histomorphometric investigation on an animal model. The mean net contribution of the Bio surface to the increase in bone implant contact (BIC) with reference to the turned, machined surface was evaluated at 7.94 % (BIC/week), within the first five weeks of healing. The contribution was expressed as the difference in the osseointegration rates ( BIC/'healing time) between the implants with alkali modified surface (Bio surface) and those with turned, machined surface. The surface characteristics that differed between the implant surfaces, i.e. surface morphology, specific surface area, contact angle, hydroxylation/hydration, may represent factors that influence the rate of osseointegration.

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Erratum to: Biomechanical and histological evaluation of four different titanium implant surface modifications: an experimental study in the rabbit tibia

Clinical Oral Investigations ◽

10.1007/s00784-015-1507-3 ◽

2015 ◽

Vol 19 (7) ◽

pp. 1699-1699 ◽

Cited By ~ 2

Author(s):

José Luis Calvo-Guirado ◽

Marta Satorres ◽

Bruno Negri ◽

Piedad Ramirez-Fernandez ◽

Jose Eduardo Maté-Sánchez de Val ◽

...

Keyword(s):

Experimental Study ◽

Titanium Implant ◽

Surface Modifications ◽

Histological Evaluation ◽

Implant Surface ◽

Rabbit Tibia ◽

Titanium Implant Surface

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Research Progress on the Biochemical Modification of Titanium Implant Surface

Medicinal Chemistry ◽

10.4172/2161-0444.1000224 ◽

2014 ◽

Vol 4 (11) ◽

Author(s):

Yingjie Mao

Keyword(s):

Titanium Implant ◽

Research Progress ◽

Implant Surface ◽

Biochemical Modification ◽

Modification Of Titanium ◽

Titanium Implant Surface

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Bone Morphogenetic Protein Coating on Titanium Implant Surface: a Systematic Review

Journal of Oral and Maxillofacial Research ◽

10.5037/jomr.2017.8201 ◽

2017 ◽

Vol 8 (2) ◽

Cited By ~ 14

Author(s):

Haim Haimov ◽

Natali Yosupov ◽

Ginnady Pinchasov ◽

Gintaras Juodzbalys

Keyword(s):

Systematic Review ◽

Bone Morphogenetic Protein ◽

Titanium Implant ◽

Implant Surface ◽

Morphogenetic Protein ◽

Protein Coating ◽

Titanium Implant Surface

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Positive regulation of Porphyromonas gingivalis lipopolysaccharide-stimulated osteoblast functions by strontium modification of an SLA titanium implant surface

Journal of Biomaterials Applications ◽

10.1177/0885328219878836 ◽

2019 ◽

Vol 34 (6) ◽

pp. 802-811

Author(s):

Jin-Woo Park

Keyword(s):

Porphyromonas Gingivalis ◽

Titanium Implant ◽

Positive Regulation ◽

Implant Surface ◽

Porphyromonas Gingivalis Lipopolysaccharide ◽

Titanium Implant Surface

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State of Osseointegrated Titanium Implant Surfaces in Topographical Aspect

Journal of Nanoscience and Nanotechnology ◽

10.1166/jnn.2018.16381 ◽

2018 ◽

Vol 18 (12) ◽

pp. 8016-8028 ◽

Cited By ~ 1

Author(s):

Xingying Qi† ◽

Yuli Shang ◽

Lei Sui

Keyword(s):

Titanium Implant ◽

World Market ◽

Implant Surface ◽

Preparation Methods ◽

Clinical Investigations ◽

Modify Surface ◽

Metallic Biomaterial ◽

Review State ◽

Titanium Implant Surface ◽

Selection Of

Titanium is a primary metallic biomaterial widely used in dental implants because of its favorable mechanical properties and osseointegration capability. Currently, increasing interests have been taken in the interaction between titanium implant surface and surrounding bone tissue, particularly in surface topographical aspect. There are currently several techniques developed to modify surface topographies in the world market of dental implant. In this review, state of titanium implant surfaces in topographical aspect is presented from relatively smooth surfaces to rougher ones with microtopographies and/or nanotopographies. Each surface is summarized with basic elaborations, preparation methods, mechanisms for cellular responses and current availabilities. It has been demonstrated that rough surfaces evolving from micro- to nano-scale, especially hierarchical micro-and nanotopographies, are favorable for faster and stronger osseointegration. Further experimental and clinical investigations will aid in the optimization of surface topography and clinical selection of suitable implants.

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