Evaluation of interstitial cells of Cajal in patients with severe colonic inertia requiring surgery: a clinical-pathological study

2017 ◽  
Vol 19 (5) ◽  
pp. 462-467 ◽  
Author(s):  
M. Cohen ◽  
D. Cazals-Hatem ◽  
H. Duboc ◽  
J.-M. Sabate ◽  
S. Msika ◽  
...  
Keyword(s):  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Colonic Inertia ◽  
Pathological Study ◽  
Cells Of Cajal

Sa2032 Interest in a Morphological Evaluation of Interstitial Cells of Cajal (ICC) in Patients With Severe Colonic Inertia (SCI) Requiring Subtotal Colectomy. A Case-Control Study

2014 ◽  
Vol 146 (5) ◽  
pp. S-359-S-360
Author(s):  
Mathilde Cohen ◽  
Dominique Cazals-Hatem ◽  
Yves Panis ◽  
Jean-Marc Sabate ◽  
Simon Msika ◽  
...  
Keyword(s):  
Subtotal Colectomy ◽  
Interstitial Cells Of Cajal ◽  
Case Control Study ◽  
Interstitial Cells ◽  
Case Control ◽  
Colonic Inertia ◽  
Morphological Evaluation ◽  
Cells Of Cajal ◽  
Control Study

Possible relationship between deficiency of interstitial cells of Cajal and colonic inertia in a patient with colon malfixation

2002 ◽  
Vol 37 (6) ◽  
pp. 483-484 ◽  
Author(s):  
Hui Chen ◽  
Koji Isozaki ◽  
Masanori Nakahara ◽  
Kazuo Kinoshita ◽  
Yasuhisa Shinomura ◽  
...  
Keyword(s):  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Colonic Inertia ◽  
Cells Of Cajal

Interstitial Cells of Cajal in Patients With Constipation due to Total Colonic Inertia

2006 ◽  
Vol 19 (3) ◽  
pp. 147-153 ◽  
Author(s):  
Ahmed Shafik ◽  
Ali A. Shafik ◽  
Olfat El-Sibai ◽  
Ismail A. Shafik
Keyword(s):  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Colonic Inertia ◽  
Cells Of Cajal

Decreased density of interstitial cells of cajal and malformations of the enteric nervous system in patients with slow transit consitpation and megacolon

2001 ◽  
Vol 120 (5) ◽  
pp. A332-A332
Author(s):  
T WEDEL ◽  
J SPIEGLER ◽  
S SCHRADER ◽  
H VONKOSCHITZKY ◽  
U ROBLICK ◽  
...  
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Slow Transit ◽  
Cells Of Cajal

Sodium current in human small intestinal interstitial cells of cajal

2001 ◽  
Vol 120 (5) ◽  
pp. A201-A201 ◽  
Author(s):  
P STREGE ◽  
A RICH ◽  
Y OU ◽  
S GIBBONS ◽  
M SARR ◽  
...  
Keyword(s):  
Interstitial Cells Of Cajal ◽  
Sodium Current ◽  
Interstitial Cells ◽  
Small Intestinal ◽  
Cells Of Cajal

Effects of Morphine on Interstitial Cells of Cajal in Rabbit Colon and Small Intestinal Transit: An Experimental Study

2020 ◽  
Vol 20 (3) ◽  
pp. 240-246
Author(s):  
Heng Yang ◽  
Xiao-Ju Jin ◽  
Hong Luo ◽  
Yuan-Hai Li
Keyword(s):  
Protein Expression ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Saline Control ◽  
Morphine Group ◽  
Small Intestinal Transit ◽  
Medium Concentration ◽  
Epidural Puncture ◽  
Mrna And Protein Expression ◽  
Cells Of Cajal

Objective: This study aims to investigate the effect of morphine with naloxone on intestinal peristalsis and the number of interstitial cells of Cajal (ICC) in colon tissues of rabbits. Methods: Thirty rabbits were randomly divided into five groups (n=6, each group): saline control group (NS group), low concentration of morphine group (L group), medium concentration of morphine group (M group), high concentration of morphine group (H group), medium concentration of morphine and naloxone mixed with antagonist group (NM group). Rabbits in these five groups were administered with an epidural puncture tube and dorsal epidural analgesia pump, and were continuously infused for seven days. Fecal characteristics were observed, and the ink propulsion rate was calculated. The expression level of ICC C-kit protein in colon tissues was tested by western blot. Results: The stool characteristics in the L, M and H groups were more severe than those in the NS and NM groups. Furthermore, the intestinal propulsion rate in the L, M and H groups was lower than that in the NS and NM groups. The C-kit mRNA and protein expression in the colon of rabbits were significantly lower in the L, M and H groups, when compared to the NS and NM groups. Conclusions: Naloxone blocked the mRNA and protein expression of C-kit, and improved intestinal motor function.

Is there a Role for Human Pluripotent Stem Cells in Modelling Interstitial Cells of Cajal and Gut Motility Disorders?

2015 ◽  
Vol 10 (3) ◽  
pp. 251-257 ◽  
Author(s):  
Wenbo Meng ◽  
Jerry Zhou ◽  
Ross Elliott ◽  
Patricia Murphy ◽  
Vincent Ho ◽  
...  
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Human Pluripotent Stem Cells ◽  
Gut Motility ◽  
Motility Disorders ◽  
Cells Of Cajal
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