Do we have enough Foreknowledge to predict the low anterior resection syndrome (LARS) score preoperatively?

2020 ◽  
Vol 22 (10) ◽  
pp. 1445-1445 ◽  
Author(s):  
H. Essangri ◽  
M. A. Majbar ◽  
A. Benkabbou ◽  
Z. Belkhadir ◽  
L. Amrani ◽  
...  
Keyword(s):  
Anterior Resection ◽  
Low Anterior Resection ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Lars Score

scholarly journals Validation of the moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research.Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria.Results: The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

scholarly journals Low Anterior Resection Syndrome in Adults with Rectal Cancer in China: a Case Series Analysis

2021 ◽  
Author(s):  
Yuan Qiu ◽  
Yu Pu ◽  
Haidi Guan ◽  
Weijie Fan ◽  
Shuai Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Recovery Time ◽  
Colorectal Anastomosis ◽  
Postoperative Recovery ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Lars Score

AbstractLow anterior resection syndrome (LARS) comprises a collection of symptoms affecting patients’ defecation after restorative surgery for rectal cancer. The aim of this work was to study the incidence and risk factors for LARS in China. Rectal cancer patients undergoing total mesorectal excision and colorectal anastomosis between May 2012 and January 2015 were identified from a single center. The patients completed the LARS score questionnaire through telephone. The clinical and pathological factors that may influence the occurrence of LARS were analyzed using univariate and multivariate logistic regression analysis. The influence of postoperative recovery time and pelvic dimensions on the occurrence of LARS was also analyzed. This study included 337 patients, at an average age of 61.03 SD11.32. The mean LARS score of the patients was 14.08 (range 0–41). A total of 126 patients (37.4%) developed LARS after surgery, including 63 (18.7%) severe cases. Compared with the scores within the initial 6 postoperative months, the LARS scores of the patients in 6~18 months after the surgery showed significant reductions (p < 0.01). In multivariate analysis, lower locations of anastomosis, pre-surgery radiotherapy, and shorter postoperative recovery time were significant predisposing factors for LARS. A subgroup analysis revealed that patients suffering from LARS over 18 months after surgery were found to have a significantly shorter interspinous distance than those without LARS (p < 0.05). LARS could improve over time after surgery. Lower anastomotic level and pre-surgery radiotherapy are risk factors for LARS.

scholarly journals Awareness and Knowledge of Low Anterior Resection Syndrome (Lars) in Colorectal Surgeons: A Cross-sectional Survey

2020 ◽  
Author(s):  
Sen Hou ◽  
Fan Liu ◽  
Peng Guo ◽  
Yingjiang Ye
Keyword(s):  
Anterior Resection ◽  
Low Anterior Resection ◽  
Multivariate Logistic Regression Analysis ◽  
Effective Rate ◽  
Cross Sectional Survey ◽  
Low Anterior Resection Syndrome ◽  
Cross Sectional ◽  
Anterior Resection Syndrome ◽  
Lars Score ◽  
Colorectal Surgeons

Abstract Background More than 50% patients suffered from low anterior resection syndrome (LARS) after low anterior resection, and their quality of life is predominantly determined by colorectal surgeons’ awareness and knowledge of LARS. We conducted the survey to find out the weakness in the management of patients' functional recovery after surgery and explore targeted training pathways to improve doctor’s ability to deal with LARS. Methods An anonymous paper-based survey among colorectal surgeons was performed across the country. Results 252 questionnaires were collected and analyzed with the effective rate of 86.6%. Most of the respondents were highly educated and experienced in gastroenterology. The mean age was 39.9 ± 9.20 years. In multivariate Logistic regression analysis, surgeons with MD, PhD degree (OR: 2.843, 95%CI: 1.441-5.609, p = 0.003) and national academic membership (OR: 2.063, 95%CI: 1.010-4.214, p = 0.047) were associated with surgeons’ emphasis on follow-up. 65.1% of respondents underestimated the prevalence of LARS. Chief/deputy chief, national academic membership and annual surgeries ≥ 50 (42.7% vs 29.4%, p=0.033; 46.4% vs 30.0%, p=0.007; 46.0% vs 31.6%, p=0.021) were associated with high diagnostic rate of LARS but none of these factors were statistically significant in multivariate analysis. LARS score was the most popular scale in the evaluation of LARS severity. The feedback of the most common postoperative anorectal disorders by colorectal surgeons was significantly different from the items listed in the LARS score. 48.4% of respondents use drugs to treat LARS but therapies varied from surgeons to surgeons. Conclusions There is a lack of knowledge relating to LARS in colorectal surgeons. Clinical guidelines should be developed to guide medical staff in effective management of patients with LARS.

scholarly journals Validation of the Moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research.Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria.Results: The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

scholarly journals Validation of Korean Version of Low Anterior Resection Syndrome Score Questionnaire

2020 ◽  
Vol 36 (2) ◽  
pp. 83-87
Author(s):  
Chang Woo Kim ◽  
Woon Kyung Jeong ◽  
Gyung Mo Son ◽  
Ik Yong Kim ◽  
Ji Won Park ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Convergent Validity ◽  
Radical Surgery ◽  
Low Anterior Resection Syndrome ◽  
Discriminative Validity ◽  
Anterior Resection Syndrome ◽  
Korean Version ◽  
Lars Score

Purpose: Patients who undergo radical surgery for rectal cancer often experience low anterior resection syndrome (LARS). Symptoms of this syndrome include frequent bowel movements, gas incontinence, fecal incontinence, fragmentation, and urgency. The aim of this study was to investigate the convergent validity, discriminative validity, and reliability of the Korean version of the LARS score questionnaire.Methods: The English LARS score questionnaire was translated into Korean using the forward-and-back translation method. A total of 146 patients who underwent radical surgery for rectal cancer answered the Korean version of the LARS score questionnaire including an anchor question assessing the impact of bowel function. Participants answered the questionnaire once more after 2 weeks.Results: The Korean LARS score questionnaire showed high convergent validity in terms of high correlation between the LARS score and quality of life (perfect fit 55.5% vs. moderate fit 37.6% vs. no fit 6.8%, respectively; P < 0.001). The LARS score also showed good discriminative validity between groups of patients differing by sex (29 for males vs. 25 for females; P = 0.014), tumor level (29 for ≤8 cm vs. 24 for >8 cm; P = 0.021), and radiotherapy (32 for yes vs. 24 for no; P = 0.001). The LARS score also demonstrated high reliability at test-retest with no difference between scores at the first and second tests (intraclass correlation coefficient: Q1 = 0.932; Q2 = 0.909, Q3 = 0.944, Q4 = 0.931, and Q5 = 0.942; P < 0.001, respectively).Conclusion: The Korean version of the LARS score questionnaire has proven to be a valid and reliable tool for measuring LARS in Korean patients with rectal cancer.

scholarly journals Validation of the Moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research. Methods The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria. Results The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

Normative Data for the Low Anterior Resection Syndrome Score (LARS Score)

2019 ◽  
Vol 269 (6) ◽  
pp. 1124-1128 ◽  
Author(s):  
Therese Juul ◽  
Hossam Elfeki ◽  
Peter Christensen ◽  
Søren Laurberg ◽  
Katrine J. Emmertsen ◽  
...  
Keyword(s):  
Anterior Resection ◽  
Low Anterior Resection ◽  
Normative Data ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Lars Score

scholarly journals Validation of the arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Validity Assessment ◽  
Lars Score

Abstract Purpose: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research. Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria. Results: The arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, Chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

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