scholarly journals Validation of the moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research.Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria.Results: The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

scholarly journals Validation of the Moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research.Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria.Results: The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

scholarly journals Validation of the Moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research. Methods The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria. Results The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

scholarly journals Validation of the Moroccan arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Moroccan Arabic ◽  
Lars Score

Abstract Background: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this observational study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research.Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment, while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria.Results: The Moroccan Arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Moroccan Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings. Trial registration: This prospective study is registered on the clinical trials database(ClinicalTrial.gov) under the number NCT04128657

scholarly journals Validation of the arabic version of the low anterior resection syndrome score

2020 ◽  
Author(s):  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Amine Benkabbou ◽  
Laila Amrani ◽  
Raouf Mohsine ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Internal Consistency ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Bowel Dysfunction ◽  
Arabic Version ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Validity Assessment ◽  
Lars Score

Abstract Purpose: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. The aim of this study is to translate this tool into arabic and test its psychometric properties in rectal cancer patients, in order to ease its use in clinical practice and future research. Methods: The LARS questionnaire was translated to arabic and administered to a total of 143 patients. A subgroup of 42 patients took the test twice for test-retest reliability. Internal consistency was examined through cronbach’s alpha. The score results were correlated to the EORTC QLQ-C30 questionnaire for convergent validity assessment while discriminant validity was established through the ability of the LARS score to differentiate patients with different clinical and pathological criteria. Results: The arabic version of the LARS score was completed by 143 patients. The internal consistency was demonstrated through a cronbach alpha score of 0.66. The agreement between the test and retest was established by a Bland Altman plot with 95% limits of agreement. 85.6% of patients remained in the same LARS category. The LARS score showed negative correlation with all five of the QLQ-C30 functional scales as well as positive correlation to the diarrhea symptom scale. The questionnaire score differed between patients according to their tumor location, Chemoradiotherapy, type of mesorectal excision and anastomosis. Conclusion: The Arabic version of the LARS score shows good psychometric properties and can be used for bowel dysfunction assessment in clinical and research settings.

Do we have enough Foreknowledge to predict the low anterior resection syndrome (LARS) score preoperatively?

2020 ◽  
Vol 22 (10) ◽  
pp. 1445-1445 ◽  
Author(s):  
H. Essangri ◽  
M. A. Majbar ◽  
A. Benkabbou ◽  
Z. Belkhadir ◽  
L. Amrani ◽  
...  
Keyword(s):  
Anterior Resection ◽  
Low Anterior Resection ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Lars Score

scholarly journals Quality of Life and Bowel Dysfunction after Transanal Endoscopic Microsurgery for Rectal Cancer: One Third of Patients Experience Major Low Anterior Resection Syndrome

2019 ◽  
Vol 37 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Maarten van Heinsbergen ◽  
Jeroen W. Leijtens ◽  
Gerrit D. Slooter ◽  
Maryska L. Janssen-Heijnen ◽  
Joop L. Konsten
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Transanal Endoscopic Microsurgery ◽  
Bowel Dysfunction ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Endoscopic Microsurgery

Background/Aims: The low anterior resection syndrome (LARS) severely affects quality of life (QoL) after rectal cancer surgery. Studies investigating LARS and the effect on QoL after transanal endoscopic microsurgery (TEM) for rectal cancer are scarce. The aim of our study was to assess bowel dysfunction and QoL after TEM. Methods: Seventy-three ­patients who underwent TEM for stage I rectal cancer were included in this single-centre, cross-sectional study Bowel dysfunction was assessed by the LARS-Score, QoL by the ­European Organization for the Research and Treatment of Cancer QLQ-C30 and -CR29 questionnaires. Results: Fifty-five respondents (75.3%) could be included for the analyses. The median interval since treatment was 4.3 years, and the median age at the follow-up point was 72 years. “Major LARS” was observed in 29% of patients and “minor LARS” in 26%. Female gender (OR 4.00; 95% CI 1.20–13.36), neo-adjuvant chemoradiotherapy (OR 3.63; 95% CI 1.08–12.17) and specimen thickness in millimetres (OR 1.10 for each mm increase in thickness; 95% CI 1.01–1.20) were associated with the development of major LARS. Patients with major LARS fared worse in most QoL domains. Conclusion: This is the first study demonstrating major LARS after TEM treatment for rectal cancer, with a negative effect on QoL, even years after treatment. Our data provides an adequate counselling before TEM in terms of postoperative bowel dysfunction and its effect on QoL.

scholarly journals Low Anterior Resection Syndrome in Adults with Rectal Cancer in China: a Case Series Analysis

2021 ◽  
Author(s):  
Yuan Qiu ◽  
Yu Pu ◽  
Haidi Guan ◽  
Weijie Fan ◽  
Shuai Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Recovery Time ◽  
Colorectal Anastomosis ◽  
Postoperative Recovery ◽  
Low Anterior Resection Syndrome ◽  
Anterior Resection Syndrome ◽  
Lars Score

AbstractLow anterior resection syndrome (LARS) comprises a collection of symptoms affecting patients’ defecation after restorative surgery for rectal cancer. The aim of this work was to study the incidence and risk factors for LARS in China. Rectal cancer patients undergoing total mesorectal excision and colorectal anastomosis between May 2012 and January 2015 were identified from a single center. The patients completed the LARS score questionnaire through telephone. The clinical and pathological factors that may influence the occurrence of LARS were analyzed using univariate and multivariate logistic regression analysis. The influence of postoperative recovery time and pelvic dimensions on the occurrence of LARS was also analyzed. This study included 337 patients, at an average age of 61.03 SD11.32. The mean LARS score of the patients was 14.08 (range 0–41). A total of 126 patients (37.4%) developed LARS after surgery, including 63 (18.7%) severe cases. Compared with the scores within the initial 6 postoperative months, the LARS scores of the patients in 6~18 months after the surgery showed significant reductions (p < 0.01). In multivariate analysis, lower locations of anastomosis, pre-surgery radiotherapy, and shorter postoperative recovery time were significant predisposing factors for LARS. A subgroup analysis revealed that patients suffering from LARS over 18 months after surgery were found to have a significantly shorter interspinous distance than those without LARS (p < 0.05). LARS could improve over time after surgery. Lower anastomotic level and pre-surgery radiotherapy are risk factors for LARS.

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