The use of bilateral continuous erector spinae plane blocks for postoperative analgesia after right‐sided living donor hepatectomy: A feasibility study

2021 ◽  
Author(s):  
Dieter Adelmann ◽  
Mina Khorashadi ◽  
George Zhou ◽  
Sakura Kinjo ◽  
Hillary J. Braun ◽  
...  

2019 ◽  
pp. rapm-2019-100902 ◽  
Author(s):  
RyungA Kang ◽  
Ki Jinn Chin ◽  
Mi Sook Gwak ◽  
Gaab Soo Kim ◽  
Soo Joo Choi ◽  
...  

BackgroundIntrathecal morphine (ITM) provides effective postoperative analgesia in living donor hepatectomy but has significant adverse effects. Studies support the efficacy of erector spinae plane (ESP) blocks in laparoscopic abdominal surgery; we therefore hypothesized that they would provide non-inferior postoperative analgesia compared with ITM and reduce postoperative nausea/vomiting and pruritus. We conducted a randomized, controlled, non-inferiority trial to compare the analgesic efficacy of ITM and bilateral single-injection ESP blocks in laparoscopic donor hepatectomy.MethodsFifty-four donors were randomized to receive bilateral ESP blocks with 20 mL 0.5% ropivacaine (n=27) or 400 µg ITM (n=27). Primary outcome was resting pain score 24 hours postoperatively measured on an 11-point numeric rating scale. The prespecified non-inferiority limit was 1. Incidences of postoperative nausea/vomiting and pruritus were assessed.ResultsThe mean treatment difference (ESP–ITM) in the primary outcome was 1.2 (95% CI 0.7 to 1.8). The 95% CI upper limit exceeded the non-inferiority limit. Opioid consumption and all other pain measurements were similar between groups up to 72 hours postoperatively. The ESP group had significantly lower incidences of postoperative vomiting (p=0.002) and pruritus (p<0.001).ConclusionsBilateral single-injection ESP blocks resulted in higher resting pain scores 24 hours postoperatively compared with ITM and thus did not meet the study definition of non-inferiority. However, the pain intensity with ESP blocks was mild (mean pain scores <3/10) and associated with reduced incidence of postoperative vomiting and pruritus. It warrants further investigation as an analgesic option after laparoscopic living donor hepatectomy.Trial registration numberKCT0003191.



2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Shelly B. Borden ◽  
Molly K. Groose ◽  
Eric R. Simon ◽  
Aaron S. Hess ◽  
Kristopher M. Schroeder

The demand for liver transplants in the United States far exceeds the supply of organs. As need has increased, so has use of living donors. Coagulopathy and various side effects often preclude the use of neuraxial regional techniques and opioids for postoperative analgesia in patients with large “J” incisions. Here, we present a 25-year-old male undergoing a living donor hepatectomy who received quadratus lumborum catheters placed percutaneously after closure of incision and prior to emergence to provide excellent analgesia and a viable opioid-sparing approach. Quadratus lumborum catheters are a safe option for a multimodal, opioid-sparing approach to analgesia.



2020 ◽  
Author(s):  
Wei Cheng Tseng ◽  
Wei Lin Lin ◽  
Hou Chuan Lai ◽  
Teng Wei Chen ◽  
Yu Chen Chiu ◽  
...  


Author(s):  
Wei‐Cheng Tseng ◽  
Wei‐Lin Lin ◽  
Hou‐Chuan Lai ◽  
Teng‐Wei Chen ◽  
Yu‐Chen Chiu ◽  
...  


2013 ◽  
Vol 1 (1) ◽  
pp. 53-60
Author(s):  
Talia B. Baker ◽  
Felicitas Koller ◽  
Juan Carlos Caicedo


HPB ◽  
2017 ◽  
Vol 19 ◽  
pp. S113-S114
Author(s):  
M. Uribe ◽  
F. Riquelme ◽  
F. Catan ◽  
S. Uribe ◽  
W. Martinez ◽  
...  


2018 ◽  
Vol 227 (1) ◽  
pp. 24-36 ◽  
Author(s):  
Danielle Berglund ◽  
Varvara Kirchner ◽  
Timothy Pruett ◽  
Saumya Mangalick ◽  
Raja Kandaswamy ◽  
...  


Medicine ◽  
2021 ◽  
Vol 100 (32) ◽  
pp. e26708
Author(s):  
Yuye Gao ◽  
Wu Wu ◽  
Chunyu Liu ◽  
Tao Liu ◽  
Heng Xiao


2017 ◽  
Vol 50 (4) ◽  
pp. 119
Author(s):  
Kin-Shing Poon ◽  
Horng-Ren Yang ◽  
Ashok Thorat ◽  
Chun-Chieh Yeh ◽  
Yi-Ying Chiang ◽  
...  


Sign in / Sign up

Export Citation Format

Share Document