scholarly journals Snot What you Think: mucus or myxoid matrix with epithelioid cells and bubbly cytoplasm?

Cytopathology ◽  
2021 ◽  
Author(s):  
K Ludwig ◽  
R Biancotti ◽  
L Alessandrini ◽  
A Fassina
Keyword(s):  
Epithelioid Cells ◽  
Myxoid Matrix

Nevus of large spindle and/or epithelioid cells (Spitz's nevus)

1978 ◽  
Vol 114 (12) ◽  
pp. 1811-1823 ◽  
Author(s):  
C. Paniago-Pereira
Keyword(s):  
Epithelioid Cells

scholarly journals Angiosarcoma of sigmoid colon with intraperitoneal bleeding: case report and literature review

2011 ◽  
Vol 93 (6) ◽  
pp. e91-e93 ◽  
Author(s):  
Tse-Hua Lo ◽  
Mu-Shiun Tsai ◽  
Tzu-An Chen
Keyword(s):  
Sigmoid Colon ◽  
Alimentary Tract ◽  
Surgical Excision ◽  
Sigmoid Colectomy ◽  
Epithelioid Cells ◽  
Spindle Cells ◽  
Choice Of Treatment ◽  
Intraperitoneal Bleeding ◽  
Immunohistochemical Studies

Primary angiosarcomas arising from the alimentary tract are rare and only a few cases have been reported in the literature. We report a case of an angiosarcoma of the sigmoid colon with intraperitoneal bleeding but not rectal bleeding. A 21-year-old female patient received a laparotomy and a mass lesion over the sigmoid colon was found with active bleeding. A sigmoid colectomy was performed as a curative resection. Grossly, the sigmoid colon contained a kidney shaped, hemorrhagic tumour from the submucosal layer extension to the antimesenteric side. Intraluminally, the mucosa of the colon was intact. Microscopic examination revealed a high grade angiosarcoma composed of fascicles of spindle cells and solid sheets of epithelioid cells. Immunohistochemical stains revealed a positive result for CD31 and the endothelial nature of the malignancy was confirmed. Smooth muscle antigens, desmins, cytokeratins AE1/AE3 and CD117 were all negative. The patient is still alive without evidence of recurrence or metastasis at a three-year follow-up appointment. Owing to the availability of immunohistochemical studies, some atypical sarcomas would now be correctly classified as angiosarcomas. Since no optimal adjuvant treatment is effective, curative surgical excision is still the best choice of treatment.

scholarly journals Immunohistopathological response against anisakid nematode larvae and a coccidian in Micromesistius poutassou from NE Atlantic waters

2021 ◽  
Vol 95 ◽  
Author(s):  
B. Sayyaf Dezfuli ◽  
E. Simoni ◽  
G. Bosi ◽  
M. Palomba ◽  
S. Mattiucci ◽  
...  
Keyword(s):  
Sensu Stricto ◽  
Cell Swelling ◽  
Epithelioid Cells ◽  
Larval Stages ◽  
The North ◽  
Eastern Atlantic Ocean ◽  
Larval Infection ◽  
High Infection ◽  
North Eastern ◽  
Multilocus Approach

Abstract A survey on Anisakis simplex (sensu stricto (s.s.)) from blue whiting, Micromesistius poutassou, in the north-eastern Atlantic Ocean revealed the occurrence of high infection levels of third larval stages in visceral organs and flesh. Larvae were genetically identified with a multilocus approach as A. simplex (s.s.). Histochemical, immunohistochemical and ultrastructural observations were conducted on 30 M. poutassou specimens. Gonads, pyloric caeca and flesh harboured encapsulated larvae of A. simplex (s.s.) but no intense host reaction was encountered around the parasite in the above organs. In the liver, the most infected organ, the larvae co-occurred with the coccidian Goussia sp. Within the granuloma around the A. simplex (s.s.) larvae, two concentric layers were recognized, an inner mostly comprising electron-dense epithelioid cells and an outer layer made of less electron-dense epithelioid cells. Macrophages and macrophage aggregates (MAs) were abundant out of the granulomas, scattered in parenchyma, and inside the MAs, the presence of engulfed Goussia sp. was frequent. In liver tissue co-infected with Goussia sp. and A. simplex (s.s.), hepatocytes showed cytoplasmic rarefaction and acute cell swelling. Results suggest that the host-induced encapsulation of A. simplex (s.s.) larvae is a strategic compromise to minimize collateral tissue damage around the larval infection sites, to facilitate the survival of both parasite and host.

scholarly journals Laparoscopic Cystectomy of Huge Ovarian Cyst in Nulliparous Woman

2018 ◽  
Vol 13 (3) ◽  
pp. 63-65
Author(s):  
Amarnath Thakur ◽  
Ganesh Dangal ◽  
Aruna Karki ◽  
Hema Kumari Pradhan ◽  
Ranjana Shrestha ◽  
...  
Keyword(s):  
Ovarian Cyst ◽  
Abdominal Mass ◽  
Mucinous Cystadenoma ◽  
Nulliparous Woman ◽  
Surface Epithelium ◽  
Epithelioid Cells ◽  
Brenner Tumor ◽  
Laparoscopic Cystectomy

Mucinous cystadenoma arises from the totipotent surface epithelium of the ovary. Its association with Brenner tumor suggests its origin as mucinous metaplasia of the epithelioid cells. The chance of malignancy is 5–10 percent. Patients usually present with abruptly increasing abdominal mass. Cystectomy is the management of choice in these cases. It was managed by laparoscopy.

scholarly journals Cutaneous Melanomas Arising during Childhood: An Overview of the Main Entities

2021 ◽  
Vol 8 (3) ◽  
pp. 301-314
Author(s):  
Arnaud de la Fouchardière ◽  
Felix Boivin ◽  
Heather C. Etchevers ◽  
Nicolas Macagno
Keyword(s):  
Lymph Node ◽  
Regional Lymph Node ◽  
Germline Mutations ◽  
Epithelioid Cells ◽  
Superficial Spreading ◽  
Superficial Spreading Melanoma ◽  
Cancer Predisposition Syndrome ◽  
Specific Morphology ◽  
Genetic Features ◽  
Molecular Assessment

Cutaneous melanomas are exceptional in children and represent a variety of clinical situations, each with a different prognosis. In congenital nevi, the risk of transformation is correlated with the size of the nevus. The most frequent type is lateral transformation, extremely rare before puberty, reminiscent of a superficial spreading melanoma (SSM) ex-nevus. Deep nodular transformation is much rarer, can occur before puberty, and must be distinguished from benign proliferative nodules. Superficial spreading melanoma can also arise within small nevi, which were not visible at birth, usually after puberty, and can reveal a cancer predisposition syndrome (CDKN2A or CDK4 germline mutations). Prognosis is correlated with classical histoprognostic features (mainly Breslow thickness). Spitz tumors are frequent in adolescents and encompass benign (Spitz nevus), intermediate (atypical Spitz tumor), and malignant forms (malignant Spitz tumor). The whole spectrum is characterized by specific morphology with spindled and epithelioid cells, genetic features, and an overall favorable outcome even if a regional lymph node is involved. Nevoid melanomas are rare and difficult to diagnose clinically and histologically. They can arise in late adolescence. Their prognosis is currently not very well ascertained. A small group of melanomas remains unclassified after histological and molecular assessment.

Cell-to-cell communication in monolayers of epithelioid cells (MDCK) as a function of the age of the monolayer

1984 ◽  
Vol 81 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Marcelino Cereijido ◽  
Edith Robbins ◽  
David D. Sabatini ◽  
Enrique Stefani
Keyword(s):  
Cell Communication ◽  
Epithelioid Cells

scholarly journals A Rare Entity of Benign Recurring Mesenchymal Tumor of the Female Urethra

2013 ◽  
Vol 2013 ◽  
pp. 1-2
Author(s):  
Onur Telli ◽  
Haşmet Sarıcı ◽  
Berat Cem Özgür ◽  
Cem Nedim Yücetürk ◽  
Mehmet Ali Karagöz
Keyword(s):  
Lower Urinary Tract ◽  
Soft Tissue Tumor ◽  
Benign Tumor ◽  
Pathological Examination ◽  
Rare Entity ◽  
Female Urethra ◽  
Mesenchymal Tumors ◽  
Urinary Tract Symptoms ◽  
Myxoid Matrix ◽  
Lower Urinary

This is a case report of a 51-year-old female patient with benign mesenchymal tumors of paraurethral region which caused lower urinary tract symptoms. The pathological examination of the lesion was reported as angiomyxoma which is a distinct soft tissue tumor characterized by the presence of prominent myxoid matrix and numerous thin-walled blood vessels. This tumor has a predilection for the trunk, head and neck, extremities, and genitalia. It is a benign tumor, and total excision is curative. Recurrence is rare except for aggressive angiomyxomas.

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