scholarly journals S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma (cSCC) – short version, part 2: epidemiology, surgical and systemic treatment of cSCC, follow‐up, prevention and occupational disease

2020 ◽  
Vol 18 (4) ◽  
pp. 400-413 ◽  
Author(s):  
Ulrike Leiter ◽  
Markus V. Heppt ◽  
Theresa Steeb ◽  
Teresa Amaral ◽  
Andrea Bauer ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Actinic Keratosis ◽  
Occupational Disease ◽  
Systemic Treatment ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Short Version ◽  
S3 Guideline

Patients with low-risk cutaneous squamous cell carcinoma do not require extended out-patient follow-up

2017 ◽  
Vol 70 (6) ◽  
pp. 852-855 ◽  
Author(s):  
A.M. Rose ◽  
K.J. Nicoll ◽  
A. Moinie ◽  
D.J. Jordan ◽  
A.T. Evans ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Low Risk

scholarly journals 108 OVOL2/ZEB1 axis restricts the transition from actinic keratosis to cutaneous squamous cell carcinoma

2020 ◽  
Vol 140 (7) ◽  
pp. S12
Author(s):  
M. Murata ◽  
T. Ito ◽  
Y. Tanaka ◽  
K. Yamamura ◽  
K. Furue ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Actinic Keratosis ◽  
Cutaneous Squamous Cell Carcinoma

scholarly journals Bilateral Diffuse Uveal Melanocytic Proliferation in a Woman with Metastatic Scalp Squamous Cell Carcinoma Treated with Cemiplimab

2021 ◽  
pp. 961-966
Author(s):  
Etti Katzburg ◽  
Dinah Zur ◽  
Orit Gutfeld ◽  
Ilya Kirgner ◽  
Zohar Habot-Wilner
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Visual Loss ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Fundus Examination ◽  
First Case ◽  
Appropriate Treatment ◽  
Underlying Malignancy

Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic intraocular syndrome that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. The IgG factor – cultured melanocyte elongation and proliferation – was found in the IgG fraction of the serum of BDUMP patients. It has been shown to be involved in melanocytic proliferation. In this case report, we describe the first case of BDUMP related to metastatic cutaneous squamous cell carcinoma (cSCC) of the scalp. A 61-year-old woman complained of decreased vision in both of her eyes, while being treated with cemiplimab (an anti-PD-1 therapy) for metastatic cSCC. Fundus examination showed hypopigmented lesions in a leopard pattern and pigmentary clumps in both eyes. Further imaging confirmed the diagnosis of BDUMP. The patient was successfully treated with plasmapheresis. During follow-up, cataract progressed in both eyes, and she underwent cataract surgery with visual acuity improvement to 20/20. BDUMP is a challenging diagnosis especially in patients treated with anti-PD-1 immunotherapy as it can be confused with drug-related effects. It is crucial to distinguish between the cases in order to allow the appropriate treatment which includes continuation of systemic anti-PD-1 for the underlying malignancy and plasmapheresis therapy for BDUMP.

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