Diagnosis of adrenocortical carcinoma via endosonography-assisted fine-needle aspiration of inferior vena cava thrombosis: First case in the literature

AbstractInferior vena cava thrombosis (IVCT) is rare and can be under-recognized. However, the associated complications and mortality may be severe. We report the first case series of IVCT observed in Taiwan with a brief literature review. Eight Taiwanese patients with IVCT between May 2012 and December 2019 were enrolled in this study. Deep venous thrombosis (DVT, 8/8) and pulmonary embolism (5/8) were reported. Various risk factors were identified, including an unretrieved inferior vena cava (IVC) filter, pregnancy, surgery, presence of lupus of anticoagulants, essential thrombocythemia, antithrombin deficiency, and hemoglobin H disease. Of note, four of our patients experienced complete IVC thrombosis with bilateral lower extremity swelling (due to DVT) and abdominal wall superficial venous dilatation, while four other patients presented with partial IVCT and unilateral DVT. The etiology, clinical characteristics, presentations, diagnosis, and treatment of IVCT were reviewed.

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Gastrointestinal: A rare tumor of inferior vena cava diagnosed by endoscopic ultrasound‐guided fine needle aspiration

Journal of Gastroenterology and Hepatology ◽

10.1111/jgh.14663 ◽

2019 ◽

Vol 34 (9) ◽

pp. 1476-1476

Author(s):

SS Rana ◽

A Savlania ◽

R Gupta ◽

P Dey

Keyword(s):

Inferior Vena Cava ◽

Endoscopic Ultrasound ◽

Fine Needle Aspiration ◽

Inferior Vena ◽

Vena Cava ◽

Needle Aspiration ◽

Rare Tumor ◽

Ultrasound Guided ◽

Fine Needle

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Inferior vena cava thrombosis as a possible cause of nephrotic-range proteinuria: two case reports

Journal of Medical Case Reports ◽

10.1186/s13256-021-03132-6 ◽

2021 ◽

Vol 15 (1) ◽

Author(s):

Yana Apostolova ◽

Patricia Mehier ◽

Salah D. Qanadli ◽

Menno Pruijm

Keyword(s):

Inferior Vena Cava ◽

Inferior Vena ◽

Vena Cava ◽

Urine Collection ◽

First Case ◽

Orthostatic Proteinuria ◽

Vena Cava Thrombosis ◽

Inferior Vena Cava Thrombosis ◽

Work Up ◽

Nephrotic Range Proteinuria

Abstract Background Nephrotic-range proteinuria is a common reason for nephrological consultation in clinical practice. The differential diagnosis is wide, and generally focuses on different forms of glomerulonephritis, but other causes should not be overlooked, as illustrated in this article. Case presentations We report two female patients with nephrotic-range proteinuria. In the first case, a 46 year old Caucasian patient who suffered from extreme obesity (Body mass index (BMI) 77 kg/m2), acute kidney injury and nephrotic-range proteinuria were discovered during an emergency consultation for acute abdominal pain. The second patient (aged 52, also Caucasian) developed stage 4 chronic kidney disease and nephrotic proteinuria (protein/creatinine ratio 1821 g/mol) after accidental rupture of the inferior vena cava during a gastric bypass operation. On split-urine collection, both had a much higher degree of proteinuria during the day than during the night, compatible with orthostatic proteinuria. At further work-up, inferior vena cava thrombosis was diagnosed in both patients, whereas renal veins were patent. Discussion After simple anticoagulation in the first case, and anticoagulation plus endovascular recanalization in the second, there was almost complete resolution of the orthostatic proteinuria and a strong improvement of the estimated glomerular filtration rate in both patients. These cases highlight that nephrotic-range proteinuria can be linked to inferior vena cava thrombosis, and that a split-urine collection may also be very useful in the diagnostic work-up of proteinuria in adults.

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