Total magnetic resonance imaging burden of cerebral small-vessel disease is associated with post-stroke depression in patients with acute lacunar stroke

2016 ◽  
Vol 24 (2) ◽  
pp. 374-380 ◽  
Author(s):  
X. Zhang ◽  
Y. Tang ◽  
Y. Xie ◽  
C. Ding ◽  
J. Xiao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Lacunar Stroke ◽  
Resonance Imaging ◽  
Post Stroke ◽  
Vessel Disease ◽  
Post Stroke Depression

scholarly journals Genetic variants of the NOTCH3 gene in the elderly and magnetic resonance imaging correlates of age-related cerebral small vessel disease

Brain ◽  
2011 ◽  
Vol 134 (11) ◽  
pp. 3384-3397 ◽  
Author(s):  
H. Schmidt ◽  
M. Zeginigg ◽  
M. Wiltgen ◽  
P. Freudenberger ◽  
K. Petrovic ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Genetic Variants ◽  
Small Vessel Disease ◽  
The Elderly ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Resonance Imaging ◽  
Vessel Disease ◽  
Age Related

scholarly journals Magnetic resonance imaging manifestations of cerebral small vessel disease

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Lei Zhao ◽  
Allan Lee ◽  
Yu-Hua Fan ◽  
Vincent C.T. Mok ◽  
Lin Shi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Resonance Imaging ◽  
Vessel Disease

scholarly journals Total Magnetic Resonance Imaging of Cerebral Small Vessel Disease Burden Predicts Dysphagia in Patients with a Single Recent Small Subcortical Infarct

2021 ◽  
Author(s):  
Lulu Zhang ◽  
Xiang Tang ◽  
Yidan Li ◽  
Juehua Zhu ◽  
Dongxue Ding ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Disease Burden ◽  
Small Vessel Disease ◽  
Small Vessel ◽  
Resonance Imaging ◽  
Post Stroke ◽  
Reactive Protein ◽  
Vessel Disease ◽  
Subcortical Infarct

Abstract Background The study was performed to identify the association between total magnetic resonance imaging burden of small vessel disease and occurrence of post-stroke dysphagia in patients with a single recent small subcortical infarct. Methods All patients with a magnetic resonance imaging-confirmed single recent small subcortical infarct underwent the water-swallowing test and volume-viscosity swallow test within the first 24 hours following admission to assess swallowing. Demographic and clinical data were extracted from our stroke database. Based on brain magnetic resonance imaging, we independently rated the presence of cerebral microbleeds, lacunes, white matter hyperintensities and enlarged perivascular spaces. The presence of each small vessel disease feature was summed in the total small vessel disease burden, ranging from 0–4. Results In total, 308 patients with a single recent small subcortical infarct were enrolled. Overall, 54 (17.5%) were diagnosed with post-stroke dysphagia. The risk factors related to post-stroke dysphagia included the following: older age, National Institute of Health Stroke Scale, higher C-reactive protein levels and higher fibrinogen levels. Based on multiple logistic regression, two variables with the most significant associations, namely, National Institute of Health Stroke Scale and total small vessel disease burden, were combined with age, gender, history of hypertension, C-reactive protein level and fibrinogen level. Conclusions Dysphagia in patients with a single recent small subcortical infarct resulted from severe small vascular disease, which was associated with systemic inflammation. This information might provide a new anti-inflammatory treatment for post-stroke dysphagia in the future.

scholarly journals Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease

2016 ◽  
Vol 36 (8) ◽  
pp. 1319-1337 ◽  
Author(s):  
François De Guio ◽  
Eric Jouvent ◽  
Geert Jan Biessels ◽  
Sandra E Black ◽  
Carol Brayne ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Perivascular Spaces ◽  
Resonance Imaging ◽  
Cross Sectional ◽  
Vessel Disease ◽  
Imaging Markers

Brain imaging is essential for the diagnosis and characterization of cerebral small vessel disease. Several magnetic resonance imaging markers have therefore emerged, providing new information on the diagnosis, progression, and mechanisms of small vessel disease. Yet, the reproducibility of these small vessel disease markers has received little attention despite being widely used in cross-sectional and longitudinal studies. This review focuses on the main small vessel disease-related markers on magnetic resonance imaging including: white matter hyperintensities, lacunes, dilated perivascular spaces, microbleeds, and brain volume. The aim is to summarize, for each marker, what is currently known about: (1) its reproducibility in studies with a scan–rescan procedure either in single or multicenter settings; (2) the acquisition-related sources of variability; and, (3) the techniques used to minimize this variability. Based on the results, we discuss technical and other challenges that need to be overcome in order for these markers to be reliably used as outcome measures in future clinical trials. We also highlight the key points that need to be considered when designing multicenter magnetic resonance imaging studies of small vessel disease.

scholarly journals Large Perivascular Spaces Visible on Magnetic Resonance Imaging, Cerebral Small Vessel Disease Progression, and Risk of Dementia

2017 ◽  
Vol 74 (9) ◽  
pp. 1105 ◽  
Author(s):  
Jie Ding ◽  
Sigurður Sigurðsson ◽  
Pálmi V. Jónsson ◽  
Gudny Eiriksdottir ◽  
Andreas Charidimou ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Disease Progression ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Perivascular Spaces ◽  
Resonance Imaging ◽  
Vessel Disease
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