Langerhans cell markers CD1a and CD207 are the most rapidly responding genes in lesional psoriatic skin following adalimumab treatment

2017 ◽  
Vol 26 (9) ◽  
pp. 804-810 ◽  
Author(s):  
Line Raaby ◽  
Cecilia Rosada ◽  
Ane Langkilde ◽  
Kristina Lystlund Lauridsen ◽  
Hanne Vinter ◽  
...  

1996 ◽  
Vol 21 (5) ◽  
pp. 325-329 ◽  
Author(s):  
P.C.M. VAN DE KERKHOF ◽  
M.J.P. GERRITSEN ◽  
E.M.G.J. DE JONG


2001 ◽  
Vol 28 (3) ◽  
pp. 115-122 ◽  
Author(s):  
Jacek Szepietowski ◽  
Craig Walker ◽  
John A.A. Hunter ◽  
Roderick C. McKenzie


2009 ◽  
Vol 160 (2) ◽  
pp. 319-324 ◽  
Author(s):  
C. Johansen ◽  
P.A. Usher ◽  
R.B. Kjellerup ◽  
D. Lundsgaard ◽  
L. Iversen ◽  
...  


2016 ◽  
Vol 11 (6) ◽  
pp. 891-893 ◽  
Author(s):  
Matteo Becatti ◽  
Victoria Barygina ◽  
Giacomo Emmi ◽  
Elena Silvestri ◽  
Niccolò Taddei ◽  
...  




2020 ◽  
Vol 47 (5) ◽  
Author(s):  
Toshiyuki Yamamoto ◽  
Kazuo Kurihara ◽  
Yoshiki Tokura


2020 ◽  
Vol 117 (28) ◽  
pp. 16465-16474 ◽  
Author(s):  
Charlotte Hurabielle ◽  
Verena M. Link ◽  
Nicolas Bouladoux ◽  
Seong-Ji Han ◽  
Eric Dean Merrill ◽  
...  

Under steady-state conditions, the immune system is poised to sense and respond to the microbiota. As such, immunity to the microbiota, including T cell responses, is expected to precede any inflammatory trigger. How this pool of preformed microbiota-specific T cells contributes to tissue pathologies remains unclear. Here, using an experimental model of psoriasis, we show that recall responses to commensal skin fungi can significantly aggravate tissue inflammation. Enhanced pathology caused by fungi preexposure depends on Th17 responses and neutrophil extracellular traps and recapitulates features of the transcriptional landscape of human lesional psoriatic skin. Together, our results propose that recall responses directed to skin fungi can directly promote skin inflammation and that exploration of tissue inflammation should be assessed in the context of recall responses to the microbiota.





2017 ◽  
Vol 14 (3) ◽  
pp. 161-166
Author(s):  
Amira A. Abdel-Motaleb ◽  
Doaa S. Sayed ◽  
Hanan Morsy ◽  
Abeer E.M. Refaiy ◽  
Noha A. Abo El-Hagag ◽  
...  


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