Intravascular volumes evaluated by a carbon monoxide rebreathing method in patients undergoing chronic hemodialysis

2020 ◽  
Vol 24 (2) ◽  
pp. 252-260 ◽  
Author(s):  
Tobias Bomholt ◽  
Sara Larsson ◽  
Marianne Rix ◽  
Sarah Rytter ◽  
Bo Feldt‐Rasmussen ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Chronic Hemodialysis ◽  
Rebreathing Method

Lung diffusing capacity: rebreathing method, applicability in nonuniform ventilation

1965 ◽  
Vol 20 (1) ◽  
pp. 99-102 ◽  
Author(s):  
P. S⊘lvsteen
Keyword(s):  
Carbon Monoxide ◽  
Nonuniform Distribution ◽  
Diffusing Capacity ◽  
Carbon Monoxide Concentration ◽  
Straight Line ◽  
Co Concentration ◽  
Concentration Changes ◽  
Rectilinear Section ◽  
Rebreathing Method

We have calculated how the carbon monoxide concentration changes when subjects with different distributions of ventilation and lung diffusing capacity (Dl) respire in a small bag. The curve [loge CO concentration in the bag] versus [time] will sooner or later appear as a straight line. Dl is calculated from the slope of the rectilinear section of the curve and from lung and bag volume. If the curve becomes rectilinear within the period considered, Dl is calculated too low. In some cases the curve will not be rectilinear until more than 45 sec have passed, but will appear to be rectilinear during the period from 30 to 45 sec. If such an experiment is discontinued when 45 sec (the usual duration of experiment) have passed, Dl can be calculated at too high, at correct, or at too low values. nonuniform distribution of lung diffusing capacity Submitted on February 18, 1964

scholarly journals CORP: The assessment of total hemoglobin mass by carbon monoxide rebreathing

2017 ◽  
Vol 123 (3) ◽  
pp. 645-654 ◽  
Author(s):  
Christoph Siebenmann ◽  
Stefanie Keiser ◽  
Paul Robach ◽  
Carsten Lundby
Keyword(s):  
Carbon Monoxide ◽  
Total Hemoglobin ◽  
Time Period ◽  
Accuracy And Precision ◽  
Molar Weight ◽  
Steady Improvement ◽  
Hemoglobin Mass ◽  
Rebreathing Method

In this Cores of Reproducibility in Physiology (CORP) article, we present the theory and practical aspects of the carbon monoxide (CO) rebreathing method for the determination of total hemoglobin mass in humans. With CO rebreathing, a small quantity of CO is diluted in O2and rebreathed for a specified time period, during which most of the CO is absorbed and bound to circulating hemoglobin. The dilution principle then allows calculation of the total number of circulating hemoglobin molecules based on the number of absorbed CO molecules and the resulting changes in the fraction of carboxyhemoglobin in blood. Total hemoglobin mass is derived by multiplication with the molar weight of hemoglobin. CO rebreathing has been used for >100 yr and has undergone steady improvement so that today excellent values in terms of accuracy and precision can be achieved if the methodological precautions are carefully followed.

Haemoglobin Mass in an Anaemic Female Endurance Runner Before and After Iron Supplementation

2011 ◽  
Vol 6 (1) ◽  
pp. 137-140 ◽  
Author(s):  
Laura A. Garvican ◽  
Louisa Lobigs ◽  
Richard Telford ◽  
Kieran Fallon ◽  
Christopher J. Gore
Keyword(s):  
Carbon Monoxide ◽  
Iron Deficiency ◽  
Iron Supplementation ◽  
Endurance Athlete ◽  
Haemoglobin Concentration ◽  
Deficiency Anemia ◽  
Endurance Runner ◽  
Before And After ◽  
Haemoglobin Mass ◽  
Rebreathing Method

Haemoglobin mass in a female endurance athlete was measured via carbon monoxide rebreathing upon diagnosis of iron-deficiency anemia (haemoglobin concentration = 8.8 g/dL, ferritin = 9.9 ng/mL) and regularly during treatment thereafter. Haemoglobin mass increased by 49% in the 2 wk following an intramuscular iron injection and continued to increase with oral iron supplementation for 15 wk. The presented case illustrates that haemoglobin mass is readily responsive to iron supplementation in a severely iron-defcient anemic athlete and that changes can be tracked efficiently using the CO-rebreathing method.

scholarly journals THE MEASUREMENT OF PULMONARY DIFFUSING CAPACITY FOR CARBON MONOXIDE BY A REBREATHING METHOD*†

1959 ◽  
Vol 38 (11) ◽  
pp. 2073-2086 ◽  
Author(s):  
Benjamin M. Lewis ◽  
Tai-Hon Lin ◽  
Frances E. Noe ◽  
Ernest J. Hayford-Welsing ◽  
Erma Flaherty
Keyword(s):  
Carbon Monoxide ◽  
Diffusing Capacity ◽  
Pulmonary Diffusing Capacity ◽  
Rebreathing Method

Replicate Measurements of Haemoglobin Mass during a Single Day are Feasible and Precise

2015 ◽  
Vol 36 (05) ◽  
pp. e19-e23 ◽  
Author(s):  
N. Naef ◽  
T. Steiner ◽  
J. Wehrlin
Keyword(s):  
Carbon Monoxide ◽  
Altitude Training ◽  
Confidence Limits ◽  
Healthy Men ◽  
Typical Error ◽  
Before And After ◽  
Haemoglobin Mass ◽  
High Level ◽  
Replicate Measurements ◽  
Rebreathing Method

AbstractDuplicate haemoglobin mass (Hbmass) measurements are recommended before and after altitude training sojourns to identify individual adaptations in athletes with a high level of certainty. Duplicate measurements reduce typical error (TE) and disclose measurement outliers, but are usually made on separate days, which is not a practical protocol for routine services in elite sport settings. The aim of this study was therefore to investigate whether it is safe (carboxyhaemoglobin<10%) to measure Hbmass twice on the same day and to compare TE with measurements made on separate days. 18 healthy men completed 3 different procedures to measure Hbmass twice a day with the carbon monoxide rebreathing method: A (Hbmass measured twice within 6 h), B (dito A, combined with 1 h of hyperoxic training between the tests), C (dito B, within 2 h). First Hbmass measurements of the 3 test days served as procedure D. Carboxyhaemoglobin did not exceed 10% in any procedure. TE and confidence limits for procedures A, B, C and D were 1.4% (1.0–2.1%), 1.1% (0.8–1.7%), 1.3% (1.0–2.0%) and 1.5% (1.2–2.1%), respectively. Duplicate measurements of Hbmass on the same day are feasible and show TE similar to triplicate measurements on separate days.

scholarly journals Application of the optimized carbon monoxide rebreathing method for the measurement of total haemoglobin mass in chronic liver disease

2020 ◽  
Vol 8 (6) ◽  
Author(s):  
James O.M. Plumb ◽  
James M. Otto ◽  
Shriya B. Kumar ◽  
Mark Wright ◽  
Walter Schmidt ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Total Haemoglobin Mass ◽  
Haemoglobin Mass ◽  
Total Haemoglobin ◽  
Rebreathing Method

A rebreathing method to determine carbon monoxide diffusing capacity in children: Reference values for six 18-year-olds and validation in adult volunteers

1998 ◽  
Vol 25 (3) ◽  
pp. 205-212 ◽  
Author(s):  
H. Stam ◽  
A. v. d. Beek ◽  
K. Grünberg ◽  
M. A. J. de Ridder ◽  
J. C. de Jongste ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Reference Values ◽  
Diffusing Capacity ◽  
Adult Volunteers ◽  
Rebreathing Method

Plasma volume in acute hypoxia: comparison of a carbon monoxide rebreathing method and dye dilution with Evans' blue

1998 ◽  
Vol 77 (5) ◽  
pp. 457-461 ◽  
Author(s):  
Troels Dirch Poulsen ◽  
Tom Klausen ◽  
Jean-Paul Richalet ◽  
Inge-Lis Kanstrup ◽  
Niels Fogh-Andersen ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Plasma Volume ◽  
Evans Blue ◽  
Acute Hypoxia ◽  
Dye Dilution ◽  
Rebreathing Method

Precision of the optimized carbon monoxide rebreathing method to determine total haemoglobin mass and blood volume

2013 ◽  
Vol 13 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Jérôme Durussel ◽  
Ramzy Ross ◽  
Prithvi Raj Kodi ◽  
Evangelia Daskalaki ◽  
Pantazis Takas ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Blood Volume ◽  
Total Haemoglobin Mass ◽  
Haemoglobin Mass ◽  
Total Haemoglobin ◽  
Rebreathing Method

The influence of carbon monoxide bolus on the measurement of total haemoglobin mass using the optimized CO-rebreathing method

2014 ◽  
Vol 35 (2) ◽  
pp. N11-N19 ◽  
Author(s):  
G Turner ◽  
J S M Pringle ◽  
S A Ingham ◽  
B W Fudge ◽  
A J Richardson ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Total Haemoglobin Mass ◽  
Haemoglobin Mass ◽  
Total Haemoglobin ◽  
Rebreathing Method
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